Ilpea ynorpe6a Ha JteKor BHHMare.

nno nposurajre ro yflarcrBoro

. r{yeajme zo
lnamcmaomo Mocre6u ke mpe6a da ?o npottumame nosmopHo.
. AKo u ame dononHumenHu npautana, o6pameme ce xaj Bawuom doxmop unu
Qapua4eem.
. Oeoj nex Bu e npenuuau Bau nuuuo u ae mpe6a da uu eo daeame xa dpyzu truqa, 6udejiu uoxe
da uu Haumemu d)pt! u aKo HltlHume cwtnmo u ce ucmu xaxo Bautume.

Bnarpeutnoro ynarcrBo coApxx:

l. IIImo npencmaqtea Acnupuu npomertn 100 mg u sa wmo ce ynompe6yea

2. IIImo uopa da suaeme, nped da zo seueme Acnupux npomercm 100 mg
3. Kaxo da zo seueme Acnupun npomercn l00mg
4. Moctcnu tecaxaHu dejcmsa (eQeKmu)
5 . Vyeane u pox ua ynompeda Ha Acnupuu npomercm I 00 mg

Aspirino protecU Acnnprno nporerr 100 mg racrpope3ncreHTnll ra6,rern

Ac€tylsalicylic Ncid

. AKTHBHa cynsraHunja: auernncannuunxa KnceJrHHa (100 mg)

. floMourHH cyncraHrrHll: nqeHKapeH cKpo6, qenyno3a npauroKr MgTaKpHJIHa KHCeJrrHa
-
erlJraKpHnar KononliMep l:l Aucnep3fija 3002, norxcop6ar 80, narprlyu ,{oaerruncyr4ar, r:rnK,
Tpr{eTHnutlTpaT.

Hne x a[peca na HocuTeJtor Ha oro6pennero la craaane Bo npoMer:

Bayer doo, llpercraan l,t urrao Cxonje,
Yr. Onrax llpnqd 66, lor. 4/ue:.hav.2, 1000 Cxonje

I,lue n aapeca Ha rrporr3BoanTeJror:

Bayer Bitterfeld cmbH, 06803 Bitterfeld-Wolfen, fepr,laHlrja

I, IIITO TIPETCTABYBA ACTIIPI,TH IIPOTEKT IOO MG TI 3A IIITO CE YIIOTPEEYBA

AcnHpHH nporeKT 100 mg ro cnpeqyBa rrp[nenyBaH'ero n 3rpyrqyBa[Lgro Ha KpBHHTe n;roqrlr

(rpoM6ounrn) u co roa npeBeHrrpa co3aaBar$e Ha KpBHH rpyrxH (rporrl6r), r.e. ja r.*rxr6npa arpemuHjara
Ha rpoM60unrnre.

Ilaryrare: Kyruja co 30 ra6lsu-r Bo 3 fleHrn oA no l0 ra6,rgrn.

Ac[upHH nporexr 100 mg ce ynorpe6yaa :a:

- HaManyBarbe Ha pn3[xor 3a cMpraocr xaj 6olHu co coMHeHne 3a ax)rreH rrHQapr<r Ha cpqero,
- 3a HaManyBalbe Ha px3ltKor o,q 3a6onysarra u cMprHocr raj 6onau Kor npexnBque nxsapxr ua
cpuero,
- ceKyHAapHa npeBeHqrrja Ha Mo3oqeH yAapt
- HauaflyBar$e Ha pn3r.rxor 3a rpaH3HTopHn HcxeMrrqHl uepe6posacxylapHlr
nn{aprr Ha uo:oxor xaj 6o.nur co TIA,
 AcnrpfiH@ nporeKr 100 mg

HaManyBaBe Ha p[3nl(oT 3a 3a6onyBarbe n cMpTHocT Kaj 6onHu co cTa6I.IrHa H HecraoxnHa

aHrHHa neKTopI-lc,
- npeBeHulja Ha rpoM6oeM6on[ja nocJre BacKyrapHa xnpypr ja HnH rpyr[ 3aoarH KaKo Ba np.
PTCA, CABG, Kaporn,[Ha eHAaprepeKroMHja, aprepno-BeHcKI{ npeMocryBarba,
- cnpeqyBa6e Ha ,ua6oKn aencrx rpou6o:r n 6e.noapo6Hr.r eu6o.nrn no JlonrorpajHn
uuo6nnrraurr (ua npruep xaj nororeM xNpypruxu ra$ar),
- HaManyBabe Ha pfi3rlxor ia npB aKyreH rHQapxr na cpuero xaj 6orgt.r co nore*e prrnvuu
r[arropn, na np. ure(epHa 6o,recr, xnneprrn[aeMrja, .qe6ennH4 xnneprearnja, nyue*'e,
cTapocT.

2. IIITO TPEEA AA 3HAETE TIPEA AA IO 3EMETE ACIIIIPIIH TIPOTEKT IOO MG

Henojre aa ro reuerdynorpe6ere ,reror AcnnprH nporerr 100 mg:

- axo cre npeqyBcrBlTenHt,t (&,reprx.rHr.r) Ha aueruJrc:lllHur.tlrHa KrcerrrHa tlu Ha Hexoja oa
ocraHarure cocrojrr ua AcnupxH nporexr 100 (a4aere novouHn cyncraHurt.r Ha floqeroKor oA
y narcrBoro);
- axo cre nMalre aJreprwcKa peaxutja roja HanrKysa Ha acrMa HrH Apyrn (a.neprncxn) pearuun ua
npeqyBcrBrnenHocr npr ynorpe6a na cain\wtarv ung.qpyrn He-crepotraHt axrn-nx{rauaropHrl
TEKOB'I:
- aKo [MaTe aKyreH r{trp Ha xeny,4HnxoT ItnH upeBo;
- aKo rrMare naroJtourxr{ 3roJteMeHa reraeHuaja:a xpnape*e (xeuoparlrqHa rHjarea);
- aKo rMare cu.nuo HapyueHa Qysxultja Ha upxuor Apo6;
- aro lMare crutHo HapyueHa QyHxunja xa 6y6pcme;
- axo fiMare clJlxo napyrueua Qyxxuuja Ha cpuero:
- axo MoMer.r.urHo 36Mare MerorpeKcar co HeAe[Ha,4o3a oA l5 mg nnx noseke;
- Bo nooteAeH rpr.ruecrep oa 6peuexocra (anqu .,EpeMeHocr")

Euaere noce6no aHHMareJl[H co Jteror Acnnpnx nporerr 100 mg:

. aKo cTe xHrrepceH3llTfiBHtr (aneprr.reHl.r) Ha ,apyru aHaJrreTcKr.r, anru_nuQ.lauaropax,
aHTHpeBMaT[qHH JIeKOB'I r{.ntl aKO rjMaTe lpyfh :ulepruU;
. aKo cre Ha repannja co atrtroarylaHTHn rexoBr.!;
. aKo nMare rrup Ha xeryaHr.rKor rrj|l{ aBaHaecerrrrureqHoro upeao, eruryvynaj(n xpoH[t Ha rrn]t
noBTopnlBa ynKycsa 6onecr ruru lcroprja Ha racrpouHTecrHHillHo KpBaperbe;
. aro nMare Hapyueua xenaralra SyHxur,rja;
. nMare Hapy[eHa 6y6pexHa QyHxUuja Hrr HapyueHa KapAxogacKynapHa utpxynaqr,rja (np.
Bacr(ylrapxa 6y6pexHa60recr, ronrecrrlBHa cp(eBa c.na60cr, uaualen nory^r"H, ioneua
o[epaqr.{A cenca sr}t KpBapeqKr.t Hacrauu), 6xaej(n auermcur^r\urHa KrjceJr[Ha Moxe
IonorH[TeJrHo na ro 3roreM[ pt{3[KoT oA 6y6pexno HapyuyBabe H aKyrHa 6y6pexHa
HHcytbr-rqueHur.rja;
[Mare rer]xa 4eQuqneHquja xa rlyxo:a-6-QocQar .qexnAporesa3a, auerucarrumHara
KHCeInHa MOXe Aa lH.qyrlHpa xeMon[3a tdrn xeMoJloTuqua aHer,anja. oarropare uro Moxe ro
tra
3rolreMar pH3HKor oa xeMonn3a ce np. B[coKa.{o3a, Tpecxa u.nn aryrHn nH{erqtn;
n6ynporpex Moxe aa uajae ua uxxrl6nropuror eQeKr Ha rpom6oqrruara arperauuja Ha
auer'trrcarHrlfirHa KlceJrHHa. Tpe6a .qa ro
[3Becr[Te ,aoKropor aKo [croBpeMeHo 3eMare
auerrrrcart-tu].urHa KHceJrlrHa r{ a6ynpo$eH:a xaualyra*e na 6o,rxl.

IIoce6Hu noeavnoeavsarba
HHcxIl .qo3H Ha arlerHJlczlJllrurdjtxara xnceltHa ja peAyurrpaar excxpeuujara xa yprvxara xuce.nrna. Oaa
Mor(e ra npeax3BlrKa Hana,t Ha r'txr Kaj npe,qflcnoHxpaHfi nat-treHT]t.

rlopaaa nxxN6nropHror e$exr na arperaunjara Ha rpoM6oulrlrre, auerrlJrcar!runJrHara xHceJrHHa Moxe

aa aoBeae ao 3foJleneHa reHAeHurja xor xpoapen'e. Axo levate rexoBr.r KoH coapxar aqer[ncarnqrirHa
KHceJrHH4 Be MorHMe xoncy.nrupajre ce co Baurtor Aoxrop/crovaroror, npea xHpypuxa oflepaulrja
(rx.nylynaj(r I uant,t oflepauur, np,[eHralHa ecrpaxqxja).
 AcnHprHo nporeKr 100 mg

AucrHncanuunnHare KnceJII.tHa Moxe aa HanpaBlr 6poxxocna:au H aa npeafi3Br.{Ka HanaaH Ha acrMa IUII|

Jlpyrir x{nepceH3xrrBHu peaxuuH. PH3IrKor e noro,reu xaj [aqHeHTI.t KoI] narar og 6poxxujalHa acrlra,
xpoHlqaa oncrpyrTnBHa 6oreo Ha 6e,rrre,4po6oau. arprrja ra noJIeHoB npaB n,'tu oreqeHa Ha3aJIHa
t"tyxo:a. onaa l,Icro raKa ce oaHecyBa Ha nauueHTl-t Kot{ ce npeocernHau (np. xoxtlll peKaul-ln. rlerxarbe,
ypTnKapHJa) Ha.4pyru cyncTaHunD.

Jlexonnre rolr coApxar auerHrcarnulurHa KtlceJrHHa He rpe6a aa ce Kopucrar noaonr nepHoa IlnH Bo
gncoxH ,uosl,t, 6e: xoncynrawja Ha aoxrop.

A€ua r| anon€cueHTl
Acnuprx nporerr 100 mg He rpe6a aa ro 3eMaar aeqa fi aroneclreHrn 3a reKyBalbe xa 6orec$'r co
rpecxa, ocBeH no npenopaKa Ha aoKrop H aoKonKy rpyrx reparreBrcKx MepKH He noMaraar. Kaj nexou
aupycxl.r uxQexunn, oco6eso I.rHQ,ryexua A, nuS,ryerqa 6 n Bapnqena nocrol pu3xK ra nojara Ha Pejos
cnHApoM, MHory perKa Ho xnBor-3arpo3yea,rxa cocroj6a :a roja e norpe6ua llTHa MearrqlHcKa
HnrepBeHunja. flponorrupano norpartarse oo eaxna couroj6a uoxe aa 6nae 3HaK 3a cfiHApoMor Ha Pej.

EneNenocr
Coeemyeajme ce co Bawuom doxmop utu QapNa4eam nped da setteme Suro xaxoe nex.
Axo orxpnere rexa me 6peuena :a BpeMe Ha rperMaHor co Acnrpuu nporexr 100 mg, BeaHau
anQopurpajre ro Baruxor aoKrop.
3a apeue Ha npsnor H BTopuor rpnMecrap oa 6peMeHocra reKoB Te urro co,lpxar aqernJrcalrurtnrHa
xncelrua ue rpe6a aa ce ynmpe6yraar, ocBeH aKo He ce lpelopaqaH]r o,0 aoKTop u cauo axo roa ejacuo
norpe6xo. .(oronxy ynorpe6yBare nexoBr.r rxro coApxar arrerwrcanuur.rjrHa Kr{ceJruHa H nnaHnpare Aa
:a6peuexure nrr cre Bo npBuor r.r BTopuor rprrMecrap og 6peueHocra, 4o:ara rpe6a ra ce o.qpxyBa
HficKa. a BpeMerpaeruero na repanrjara ruro e MoxHo noxparKo.
AusrnncanflunrHara KuceJrnHa e KoHTpaHHAHurjpaHa 3a BpeMe Ha rper[or rpnuecrap oa 6peueuocra,

,lloerre
Maru xonuqegtga or aKTHBHara cocrojxa auerrutcarlutt;lHa KficeruHa n xej:tHnre uera6onlrrn
rrpeM[HyaailT Bo MajqnHoro urexo, Et.gej(u Aocera He 6me:a6erexaHx HecaKaHr aejcrna xaj aerero,
neua nmpe6a Aa ce npeKHHe Aoelbero, aKo AHeaHara ao3a He HaaMr,rHyaa 150 mg. Axo ce revar
uorucoxrl ao:u (noaeke ol 150 mg asenno), naqrexrxara rpe6a 4a ro npexr{He ,qoe*ero.

B,rujarxe rpr cnoco6nocra:a so:erbe Ha asroMo6r llnn panyBan,e co MaurrtHtl

He ce:a6erexauu eQerru ap: cnoco6Hosm 3a Bo3elbe r{nt,t paKyBabe co MauHH14.

3euarre na ,apyru aexonn (ra rlrTo rpe6r aa ce BHllMaBa aKo yrrorpe6yaare apyrr .reroan)
Be uonuue da zo uuQopuupame Bawuom dorcmop uttu Qap a4e6m aKo se ame, unu neodauua cme
seuarc 6uno xoj dpyz tex, dypu u ouue rcou ce do1ueaam 6es neKapcKu pe4enm.

3€Mar$e/ynorpc6yBarbe Ha apyrll neKoBr

Be .uonutte da to uuQoptvupame Bauuom doxmop ulu Qap.waqeem arco setrame/ynompe6yeame unu axo
HeodauHa cme 3e,uate/lmompe6tue 6uto xaxoe dpyt tex, dypu u ouue xou ue ce ua neKapcKu pe4enm.

Be uo.lrxue nuQopulrpajre ro Bauruor AoKrop aKo rsroBpeMeHo ynorpe6ynare 6ano xoj o,q creaHxBe
nexoBH:
- [pyrn Hecrepora.qHr,l aHrnuuQ.nauaropun lexoot (lexoru uno ce ynmpe6yBaar 3a neKyBarse Ha
aocna,reHne r 6orxa)
- Crcreucrn myxoxopraxougn (nexoBri luro HaManyBaar 6olra n aocna-nenue)
- AHTHKoaryflaHTn, rpouOollrxqn/nuxu6nropt Ha arperaqrjara ua rpou6ounu (lexoBr.r ulro t"l-r
cuperyaaar rpou6ou[TUTe Meiyce6Ho Aa ce 3anenar x.{a Qoprrarlpaar rpyrra)/ xevocrarnun
- Anrn.qllja6erIaurl (lexotr uno ja traManyBaar rnyr(o3ara ao xprra)
- Mermpexcar (neK Irrro ce Koplrcrn 3a rperMaH Ha pax u oapereHn peBMar qHt-t Hapyuysaba)
-,{uroxclx (lex urro ro rajaxHyBa cpueBuor MycKyn)
- Balnporvxa xrcenlrHa (nex [rro ce KopHcrH 3a repantja Ha xouaylrnt Ha uotoxor)
- Ce.nerrxsun ceporoHuH nr*t6nropx (lexonll :a.nexyna*e Ha aenpecnja)
 Acnrpano nporerr 100 mg

. AI{E lHxu6nropr, (Knaca Ha neKoBH 3a HaManyBabe Ha xpsHlor npxrucox)

- .[uypcrlrqr (nexoBu lrrro ro 3roreMyBaar mtaqyBarbero na ypnnara)
- Yprro:ypn,rxn areHcu (nexona :a nexyBa*e Ha rflxr).

I4groBpeMeHara yrtorpe6a Ha JrexoBl.t Kol co,qpxar [6ynpoQeH, Moxe aa r_o Hapyun e$eKror Ha
ullxt'I6NUuja Ha xoarylaqnjara Ha Hltcxo-,qo3upattara aUerr,t;rc4rrHuHJlHa
KHceJrHna (npeseHqaja oa rpgHu
rpFXx).

Vnorpeoyaa*e ta Acr|HpHH nporerr 100 mg co xpaHa l|nl| co nljanoK

l4cToBpeMeHoTo 3eMa$e Ha Augrnncafl[qunHara xHcerHHa
orlacHocTa oa KpBaperLe Bo raclpoHtfrecTHHalHIjOT
co ajrKoxonHr{ nnjanoun ja rroleuyaa
maKT.

3. KAKO CE YIIOTPEEYBA ACTIIIPI4H NPOTEKT IOO MG

cTporo l|pll,{pyxyaajre ce xoH- ynarcrBara Ha aoKropor.
,{o:nre He cMesre ,qa ri,, MeHyBare B.nH
rtexyBarsgrora ro npexntyaare 6e: aa ce nocoBeryBare co llorffop.

OcaeH axo He e npenopatlaHo no[Haxy AcnrpHH nporeKT 100

mg ce:eua eo cneAHure Ao3x:
Axyren nHQaprr xa MrroKapror: xunurjalri aoraotr I00
ao 30-0 mg ce aaBa Haj6p3o npn coMHeBarbe 3a
MlloKap,aeH nHrlapxr. .(o:ara ua ogpxyaarre oa 100
ao 300 mg rpe6a aa c" npooon*n oo 30;;;;_-
ltQaprrHo. Iloc,re 30 aeH rpe6a Aa ce 3eMe "rapunHJa
np"4""o 3a rrpeBeHurr,a Ha pekypeHre'
MrioKapAeH uH$aprr. "o

.{oxolry :a oaaa ns,luxaquja ce ropnc.rar racrpo-pe3rrcreurHt ra6.neu, lruqrjalsara ao:a rpe6a aa ce

H3uBaKa 3a,tla ce 3a6pra pecopnpljara.

llperxo.qeu nnQaprr aa uuoxapaor: 100 ro 300 mg.[HeBHo

Cexyx4apxa npeaeuuuja ua uoaoreH yaap: 100 ao 300 rng
rHeBHo

flauuerra co rpamHropeH HcxeMXqeH qepe6posacxyrapeH Hana.4: 100

Ao 300 mg.qHeBHo
Cra6lnxa n xesra6nnua aurusa neKroprrc: 100 ao 300 mg aHenuo

llperexusja Ha rpou6oeu6onnrau no BacxynapHa xflpyprnja nlr unrepeeHqyn: 100 ,{o 300 mg anesHo
llpo$maxca ua.{-na6oxa reucra rpouoola r 6e,ro.qpo6ex eM6onx3aM: 100 Ao 300 mg
mg ceKoJ Brop aeH AHeBHo Hnx 300

Peayxaquja Ha pn:HK 3a npB MtoxapAeH r.rHQapxr: 100

mg aHelxo Hnu 300 mg ceKoj BTop
AeH

Haq H Ha ynorpeoa
Ta6ngrHre ce rortaar uerH co rojreMa t(onrqHHa Ha reqHocr,
naj.qo6po rpea 1a,{ebe ([p. co qaua 80ra].
3a rperuan xa axyren unQaprr Ha cpuero, npaara ra6lera rpe6a aa ce u:usaxa.

AcnHpnH nporerr 100 mg e HaMeHer 3a,[onrorpajna repannja.

Ba,u or Aorcop lte or.flyqn 3a aonx[Hara
Ha TpeTMaHOT.

Axo cre :ena.ne/ynorpe6r.le noro,reMa ao3a oa neKor orronKy

utro rpe6a
Axo cme zeuane/ynompe6ute nozoteua dosa od nexom AcnupuH-npomeKm
100 mg omxonxy wmo mpe6a,
eed au mpe6a da ce nocoremysame co Bawuom dorcmop *i qopro4"u^.
 Acnuprr@ nporerr 100 mg

Be uoluue BeaHau ra ro rr3Becrr4Te Baurnor aorrop, aKo ce coMHeaare Bo [pe]Io3upaHocr

co Ac[xpHH
nporercr, Toj/raa rte oalyvlr xon Mepxt rpe6a qa ce [peB3eMar, Bp3 ocHoaa Ha cepuo3Hocra
Ha
npeaornparsero/rpyerrero.
Crumounre Ha xpoHuqHo rpyerbe ce: 3arrJeMsreHocr, BprornaB[u4 3yebe Bo
],rx'Te, nopeMgryBa*e Ha
c:r).xor, norelbe, mler6e, noBpar(a6e, mano6onxa a xonQyrr.rja.
cr,umounte Ha ax)'THo rpyene uajrecro ce uaHn$ecrrpaar co nopeMeryBaH,e Ha aur.rao-6a3Hara
paMHorexa s Moxe ,qa Baprrpaar ao caojara rexuua.

Aro cre ra6oparnne aa ro 3eM€Te Jteror AclHprH nporexr 100 mg

AKo cre 3eMa.'re rroMaJra.{o3a oa Acnxpnn nporexr 100 mg aln crJ ra6op aslne
aa 3eMere eaHa Ao3a,
Torau He:emajre.qnojra,qo3a cne,(Hlror nar; eaHocraaHo npoaon)Ksre
Aa ro 3eMare Jreror KaKo ruro e
onu aHo Bo HaqHH Ha ynorpe6a urn Kaxo rtrro BH e npefiopaqaHo oa Baufior aoKTop.
E$errx no nperxHyBarse Ha repanujara co Acnuptn npoTerff 100 mg
Be voluue Aa He ro npeKxHyBare rperMaHor co Acnuptx nporexr 100 mg ce
Ao,4eKa He ce
KoHcynrHpaTe co BauHor AoKTop.

Aro lMare noBerie ]rpauaba 3a ynor?e6a aa Acnrpna nporerr I00 mg rorcy.rrnpajre ce co JIoKrop rurH
Qap"nqerr.

4. MO?|(HH HECAKAHI{ AEJCTBA

Kaxo s cr,ne rexosu x Acnxp H flporer<r 100 mg Moxe Aa HMa HecaKaH[ letcrBa.

3a6erexagn ce nop€MeryBaba Ha ropHlror u aoJ,rHror racrpolrHTecrrHareH TpaKT

co Boo61,raeH,,,Te
3HaqH l,t ctlMnroMn Kar(oruro ce, ancnencuj4 racrporrHTecrlHrulra a a6.qovnra.nsa 6onx4 perxo
racrpo[rrecrr,rHarHo BocnareHre, racrpo[HTecrrHanen utp, xoj noreHqujanHo
no per*o
IoBeAyBa Io racrpoxHrecrrHanHo xpBaperse Hnu nep$opaur.tja rapaar1 .tup. "nory
3apaau lHxn6nropuuor e0exr Ha rpoM6ouHTHTe, AcK Moxe ra 6t,1ae nosp:aua co 3roreMeg p[3HK o,'
xpBapelbe. 3a6erexaHl ce t(pBapelba KaKo trrro ce rlept,toneparnBo (pBapebe,
xeMaroMu, KpBaperte oa
Hocor, yporeH,T:rnHo KpBapebe, r'HrnaaflH' Kp'aper'a. 3a6elexann ce Bo perK'
x MHory per*r{ cnyqax
cepHo3HH KpBaperba KaKo urTo ce (pBapersa Bo racTproHHTeCTXHJrHr..rOr
TpaKT, KpBapeBe Bo MO3OXOT
(oco6eno raj na!fieHTn co HexoHTponnpaxa xuneprenrnja r,rh.nr.r llcroapeue"" ynorpa6a
alnuxeMocrarcKa. TepanHja) xon Bo o.{peAeHH cnyqau "u
Moxar aa 6rAar norexuuialso xnBore-
3arpo3yBa'{ K 1r.

Kpaaperrara Moxe aa,{oBe,[ar ao akyrHa n xpoH]tqHa xeleto ,ae0uuarxa ateunja (:apagu cxpaexoro
mrrpoxpaaperre) co cooaBernlr Kn,nH'nqKn 3'auri , c,MnroMl{ KaKo ulro ce acreHri4 6ne.q'no,
x r noneprfy:r.rj a.

3a6enexana e xeMoJl[3a H xeMon!]:Ia auerrluja xaj [aqneHTn co reux], r]opruu xa He.aocrarox Ha

r.nyxo:a-6-r[ocQar aexr-raporeHa:a (f 6<D!).

Ex.le npujaaeru 6y6pexHo ourreryoarse a aryrxa 6y6pexna rucyQlrutexuuja.

3a6elexaxn ce x[nepceH3rTr..rBHure peat<ufiH xox BxnyrryBaarcr.rHApoM Ha acrM4 necHr., Ao yMepenll

peaKqfiu x[[epceH3]rrnBHr.r peaxqHH Ha pecnnparopHxoT rpaKT,
I(OXHl.t
racTpoHHTegru.tHanHr,tor TpaKT n
xapA[oBacKynapHHor crjcreM, rmyvyaajfu.r cHMnroMr.t KiMo Hcnn,
namlna xoxrecrnj4 KapAlo-pecn[paropeH Aficrpec lpruxaptja, e.4eM, qeua]6e, pn rrn ,
, p"r^o reuK' peat(ux, aruryryoajir_r
aHaorinaKrHqeH uoK. "*ory
Muory perxo ce :a6elexyna MuHJTHBo BJroulyBan e na upnoapo6Ha $ylrurzja co 3roneMyBzu5e Ha
TpaHcaMr{Ha3 tfre.

3a6elexast ce Bp/rornaBaqa a 3yene Bo ylxrre, xor.r tuoxe aa 6aaar l,Hlr{kau}Ua 3a npe.qo3

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 Acnupuno nporerr 100 mg

Aro ra6erexrre 6nno roe oa norope cnoMeHar[Te Heca*a'u erpexrr.r, npernuere ro 3eMarL€T]o Ha
Acnrpxn nporerr 100 mg.
Ilocgrae goKrop xoj fte ja oapean rexunara Ha HecaKaHxre eQeru n ie rrr olpegu HeonxoAHrne
MepKn.
AcnupnH npor€rc 100 mg rpe6a Aa ce npexnHe BeAHarrr lrrroM fte ce nojaaar npBrrre 3Haqx Ha
npe.ryEcTBHrennocr,

5. qYBAEE I{ FOK IIA YIIOTPEEA HA ACNIPITH NPOTEKT TOO MG

Jlexom gnqjme zo xa uecms nedocmanxu sa deua!

Jlerm ga ce ryra xa reMfleparypa noA 25"C.

Por nr ynorpc6a
ra poxm Ha ynorpe6a Ha reKor e Hcneqar€H Ha JreHrHTe ra6lgrx u sa rarpoxcxam ryruja.
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Jlexom xe cttee da ce ynompe6yea no damyxom na poxom ta lmompe1a"o wmo e naeeden'ua rymuiaia.

Hlqttx xe rr3Aasatbe Ha JreKor

Jlexm uoxe ga ce ue4ana u 6e: lerapcKu peu€flr (Ep).

Arryu Hr nocJetrxa pernsrlja xe Bnrrperurroro ynrrcrBo

06.2010

Epoj nr oao6penle 3a craBarle nr Jrcror Bo rrpousr

l5-2615/08. 3 1.08.2009