Adult Critical Care IV Medication Infusion Sheet

March 2010
DRUG

STD CONC

STD DILUTION

STD FLUID
ALT FLUID

COMMON ADULT
ADMINISTRATION RATE

MAX ADMIN. RATE

MAX CONC/
REFERENCE

Administration
Central (C) or
3,4

Peripheral (P)

Abciximab

2 mg/mL (bolus)
36 mcg/mL

Bolus: 10mg/5mL
9mg/250mL

Bolus: 0.25 mg/kg

0.125 mcg/kg/min x 12 hours

10 mcg/min

1.5 mg/mL (bolus)

1.8 mg/mL

Bolus: 150mg/100mL
450mg/250mL

(use non-PVC bag)

Bolus: 150 mg over 10 min

1 mg/min x 6 hours
0.5 mg/min x 18 hours

Max dose 2.2g/ 24hr

2 mg/mL

C or P:
( 2 mg/mL)

Argatroban

1 mg/mL

250mg/250mL

D5W/NS

2 mcg/kg/min
Hepatic Failure, Heart Failure,
Multisystem organ failure start at
0.5 1 mcg/kg/min

10 mcg/kg/min

1 mg/mL

C or P

Bivalirudin

5 mg/mL

250mg/50mL

D5W/NS

Bolus: 0.75mg/kg
1.75mg/kg/hr

2.5mg/kg/hr

5mg/mL

C or P

Bumetanide

0.04 mg/mL

10mg/250mL

D5W

0.25 - 0.5 mg/hr

Cisatracurium

0.8 mg/mL

200mg/250mL

D5W / NS

Dexmedetomidine

4 mcg/mL

200mcg/50mL

NS

Bolus 0.15 mg/kg IV

0.15-0.2 mg/kg/hr
0.2 1.4 mcg/kg/hr

Diltiazem

1 mg/mL

100mg/100mL

D5W / NS

Dobutamine

2 mg/mL

500mg/250mL

1.6 mg/mL
3.2 mg/mL
0.1 mg/mL

Amiodarone

D5W / NS
D5W

2 mg/mL

C or P
Use 0.22 micron filter

For CrCl < 30mL/min: 1 mg/kg/hr

Dopamine
Drotrecogin alfa
Epinephrine
Eptifibatide

0.25 mg/mL
(undiluted)
2 mg/mL
3

C or P
C or P
C or P

15 mg/hr

D5W Premix/ NS

Bolus 0.25 mg/kg over 2 min

5-15 mg/hr
2.5-20 mcg/kg/min

4 mcg/mL
1 mg/mL

40 mcg/kg/min

12.5 mg/mL

C or P

400mg/250mL
800mg/250mL
15mg/150mL

D5W Premix/ NS

2-20 mcg/kg/min

20 mcg/kg/min

12.8 mg/mL

NS

24 mcg/kg/hr (max 135 kg)

Not to exceed 96hrs

0.1 mg/mL

C: preferred
P: large vein
C or P

64 mcg/mL
128 mcg/mL
2 mg/mL (bolus)
0.75 mg/mL

16mg/250mL
32mg/250mL
Bolus: 20mg/10mL
75mg/100mL

D5W / NS

1-10 mcg/min

RTU Premix glass vials

Bolus: 180 mcg/kg (PCI: bolus x 2)

2 mcg/kg/min

10 mg/mL

2500mg/250mL

RTU Premix/ D5W

Bolus: 500mcg/kg over 1 min

50-300 mcg/kg/min

0.8 mg/mL (bolus)

0.32 mg/mL

Bolus: 80mg/100mL
80mg/250mL

NS

Bolus: 80mg over 30 min

8 mg/hr up to 72 hrs

10 mcg/mL

1000mcg/100mL

D5W / NS

25-150 mcg/hr

1 mg/mL

D5W / NS

10-40 mg/hr

D5W Premix/ NS

1 mg/mL

C or P

Max bolus: 22.6mg

Max inf: 15 mg/hr

2 mg/mL

300 mcg/kg/min

40 mg/mL

C: preferred
P: large vein
C or P

For CrCl < 50 mL/min: 1 mcg/kg/min

Esmolol
Esomeprazaole
Acute UGI Bleed
Fentanyl
Furosemide
Heparin

100 units/mL

250mg/250mL
500mg/250mL
25,000units/250mL

Insulin

1 unit/mL

100units/100mL

NS / D5W

Bolus: 65 unit/kg
13 units/kg/hr
See Heparin Protocol
See Insulin Protocol

Isoproterenol

C or
P: ( 10 mg/mL)
C or P

160 mg/hr

20 mcg/mL

C or P

10 mg/mL

C or P
C or P

Titrate to target serum

glucose level
0.1 mcg/kg/min

C or P

16 mcg/mL

4mg/250mL

D5W / NS

0.5-20 mcg/min

Ketamine

1 mg/mL

500mg/500mL

NS

8 - 25 mg/hr

16 mcg/mL

C or P
C or P

Labetalol

2 mg/mL

500mg/250mL

D5W / NS

1-2 mg/min

C or P

Adult Critical Care IV Medication Infusion Sheet

March 2010
DRUG

STD CONC

STD DILUTION

STD FLUID
ALT FLUID

COMMON ADULT
ADMINISTRATION RATE

MAX ADMIN. RATE

MAX CONC/
REFERENCE

Administration
Central (C) or
3,4

Peripheral (P)

Lidocaine

4 mg/mL

1000mg/250mL

D5W Premix / NS

1-4 mg/min

5 mg/min

16 mg/mL

Lorazepam

0.2 mg/mL

24mg/120mL

D5W/NS

0.5-2 mg /hr

8 mg/hr

Midazolam

1 mg/mL

50mg/50mL
100mg/100mL
20mg/100mL

D5W / NS

2-4 mg/hr

20 mg/hr

1 mg/mL
2 mg/mL

D5W / NS

Bolus: 50mcg/kg over 10min

0.375-0.75 mcg/kg/min
1-10 mg/hr

1 mcg/kg/min

200mcg/mL

0.03 mcg/kg/min

6 mcg/mL

15 mg/hr

0.1 mg/mL

300 mcg/min

Milrinone

200 mcg/mL

Morphine

1 mg/mL

Nesiritide

1,3

C or P

D5W / NS

Nicardipine

0.1 mg/mL

25mg/250mL

D5W / NS

Nitroglycerin

0.2 mg/mL
0.4 mg/mL

50mg/250mL
100mg/250mL

D5W Premix/ NS

Bolus: 2mcg/kg
0.01 mcg/kg/min
5 mg/hr
Titrate by 2.5 mg/hr q15min
5-25 mcg/min

Nitroprusside

0.2 mg/mL
0.4 mg/mL
32 mcg/mL
64 mcg/mL
5 mcg/mL

50mg/250mL

D5W / NS

0.5-8 mcg/kg/min

10 mcg/kg/min

0.8 mg/mL
2
GLASS
0.8 mg/mL

8mg/250mL
16mg/250mL
500mcg/100mL

0.5 - 30 mcg/min

1 mcg/kg/min

128 mcg/mL

NS / D5W

50-100 mcg/hr

Pentobarbital

1 mg/mL

500mg/500mL

D5W/NS

Phenylephrine

400 mcg/mL

100mg/250mL

D5W / NS

Bolus: 10-15 mg/kg over 1-2hrs

0.5-4 mg/kg/hr
100-180 mcg/min

Procainamide

4 mg/mL

1000mg/250mL

Octreotide

D5W / NS

NS

Bolus: 15-18mg/kg over 30 min

1-4 mg/min
5-75 mcg/kg/min

Propofol

10 mg/mL

1000mg/100mL

10% Intralipid Premix

Rocuronium

5 mg/mL

500mg/100mL

D5W

0.15 mEq/mL
0.6 mEq/mL

150meq/1000mL
300meq/500mL

D5W

0.4 unit/mL

20units/50mL

NS/ D5W

0.04 units/min

0.4 unit/mL

100units/250mL

NS/ D5W

1 mg/mL

100mg/100mL

D5W / NS

Bolus: 20 units
0.2-0.4 units/min
Bolus: 0.1 mg/kg
0.08-0.1 mg/kg/hr

Vasopressin
Septic Shock
Vasopressin Variceal
Bleed
Vecuronium

C or P
C or P*
* site change q12
C or P
C or P

Protect from light

Protect from light

Sodium Bicarbonate

C or P

6 mcg/mL

5mg/mL

C or P
C or P

50mg/50mL
100mg/100mL
1.5mg/250mL

Norepinephrine

D5W / NS

C or P

10 mcg/mL
Goal level 20-40
mcg/mL
400mcg/min

8 mg/mL
6.4mg/mL

16 mg/mL
75 mcg/kg/min

C: preferred
P: large vein
C or P
C: preferred
P: large vein
C: preferred
P: large vein
C or P

10 mg/mL

C or P
Change tubing q12
C or P

0.15 mEq/mL

C: preferred
P: large vein

0.04 units/min

1 unit/mL

0.9 units/min

1 unit/mL

1 mg/mL

C or P

Bolus: 0.6 mg/kg

0.6 - 0.9 mg/kg/hr

To review clinical care guideline G-13.6ADULT CRITICAL CARE MEDICATIONS FOR CONTINUOUS IV INFUSION