Liver and Intestine
{P0-725
[EVALUATION OF THE INCIDENCE OF POST LIVER
‘TRANSPLANT DIABETES MELLITUS AND ITS RISK
FACTORS IN SHIRAZ TRANSPLANT CENTER
Heshmatoish Salah Aleza Mehsizadoh, Al Razmon, Soyed
‘AlMalok-Hossain. Nomazee Hospital, Shiraz Tansplant Research Center,
Shiaz, Fars, samc Repub of ran
Purpose: Post ransplant diabetes melts (PTOM) i # commen complication
ter onotooic iver traneplantation (OLT). The hfiuorce of presiting ce
bras melitus cn outcome alter OLT has no! boon weil tine. nhs SING}
we want to evaluato tho prevalence and th rik factors of poet anepiant de
betas molitus among Iver tansplartod patents
Methods: In th slut, wo evaluated 80 Iver ransplarted patents in Shiraz
(igen Transplant Cantor end civded them info 3 groups, group A wih pe
td post ansplant OM, g'oup 8 without pe ad wih post vangplent DM ars
|900p C without pre and post enspla OM. Post rasan dabetosraltus
‘fas diagnosed wih lasing Bood sugar of mee an 126 moh in serum. Age,
ot blend group, sour af organ ar ab dla wore evaluated in all patente.
Result: Group A consist of 14 (17.5%) casos, group 8 with & (5%) casos
1d group C with 62 (775%) cases. In group A,B and C respectively, moan
ago Was 9804116, 25.513 and 5225128, the MIF rato was 0.75.3 and
2.26, the provalnt BG was O, 8 and 0, source a organ was cadaver. Vi
and autoimmune hepaiisn group A anécxyplogenscirhoss n group B and
‘Cwere the most prevalent underying iseases.
‘Conclusion: In conclusion, the provalanco of pretransplant cabetoe melts
ard poat raneplant iabotos mells wae 17.5% and 18 225%, The prove
lence of pant wth de nove doles melts wes 8% Among tha evaluated
fikfacior tho sox of group B and pre Yareplant Blood sugar were statis
Siniteart
PO-726
‘AQUALITY IMPROVEMENT APPROACH TO THE
EVALUATION ALGORITHM FOR UNOS STATUS 9 LIVER
‘TRANSPLANT RECIPIENTS: ANALYSIS OF KEY QUALITY
(CHARACTERISTICS (KQCs) AND KEY QUALITY
‘VARIABLES (KOVs)
Polo De Simone, Lslana Balin, Paola Cara, Stara Petuscel,
Gaile Catalano, Chan €. Garcia, Raquel F Lermann, Franco Fippon.
ror Transplant Unt, Azienda Ospedtiera Unverstaia Pisani Psa ay.
‘Background: quaity improvement of heatheare procosaes aquiros dont
caton of key qual charactorisioe (KOs) which depard on kay qual var
Ahlos (KAN) Efiioncy of evaluation algeritys fr Iver Yansplartaon (LT)
‘smandatry lor pation selection and LT cost-efeciveress
Materials and methods: a retrospecivo review ofthe pr-LT algrth for
UNOS 3 LT recipients trom 1908 t 2004. Efiioney was the KOC and wae
‘ho rao of walisied paints fo toll rlered. KOVs were retored patent,
patois admitod and oxclued rom waits. ang reasons for excuse
Fecute: 1837 palonts woro reload and 404 (26%) wore watts. 1959
(73.7%) were orludod, 497 (96.7%) fr ER and 56 (633%) ft convalncin
fons. 273 (31.9%) prosertec HOC beyond the centr clei and 204 127.9%)
tmaor cardiovascular diseases (CVD), HCC excluded wore 207%. (78256)
attr presenpive evaluation, 34.5% (128986) ator conoulaton(p =n), and
'30:3% (74/244) on werkap complaton (p= 2}. MVD excluded ware 257%
(68/256) stor pre-onpive evaluation; 23.3% (831356) afer conetaion (p
ane), and 34.8% (8/244) on workup completion (p 0.03 and 0.0027). ERs
wore CTP Ain 100% ater pve-ometve valuation and conautaton (p=) and
imisdlagnosed HCCs in 79.8% (78794) on workup completion (p ~ 2.00001)
Conclusions: ecioney of tho aigorshm was low (25.9%). ER, HCC ane
CVD wore the major reasone for excision. Improvement of KGC might be
‘trough dicen of tne seloctonertoria wih ofrence to HCC; Keniosbon
1 ERe and eprekmnary catdovasaar workp fr MCVD.
[RESULTS OF ADULT LIVER TRANSPLANTATION WITH
WHOLE AND PARTIAL GRAFTS
(vier Boot’, Mustapie Adham', Mstmoud el Meter, Alaa Hamza’,
Phiippe Gullem’, Vincent Peyregne?. Jerome Dumorter'. Liver Transplant
ni Edouard Heriot Hospital, Lyon, France: “Wad E/ Neel Hospital, Cai,
Epp
‘Aim: to compare osu of adver taneplantation (LT) according othe type
‘tara uses
Petlons and methods. Fom decombar 1996 lo may 2004, 396 acl patents
ha LT and among them 21 (26%) ecoied a paral gah (PG) (81 ng and
{Slot ats rom spit vers and 72 ight and 8 le ris fom ving conor).
Fosule: in patons whe receive a PG, tho cnhosls was mae advanced than
in those wa had a whole gat (WG) (Cid C status: 54% ve 33.5%), the ate
‘of hepatocarcinoma was much higher (21% ve 12.9%. Tho rates of hepatic
lanery thromboes and retransplaration was comparabein both groups (0.9%
In WG vt D.8% in PG and 0.9% In WG ve 4 1% in PG), Bilary complcstions
Poster Presentations 211
were more requent in PG than in WG (125% vs 3.7%). One and 2 yar patent
Sutvials wee 90% and 86% n paints with WG and 86% and 82% oe
‘win PG. According tothe type of PG, one and 2 year pation survivals wore
‘22% and 84% with ight iver lobe rom Iving denor, 60% ans 80% wth a et
lobe fron a ving donor, 0% and 20% with aright spt lobe and €9 2% and
(082% with alt epi be.
‘Conclusions: This series domonststos thet survival of adult pavonts rece
Inga parla! Iver graft was nak alectog in soto of ther worse concons ans
the more demancing techniques compared with those naving @ whole Iver
gan,
PO-728 |
LIVING DONOR LIVER TRANSPLANTATION (LOLT) VS.
MALIGNANT/BENIGN LIVER DISEASE (LO): 8
COMPARISON IN MORBIDITY AFTER RIGHT
HEPATECTOMY
Joana Fetr, Jose Fuster, Guillermo Alvarez, Josep Natt
“Constantino Fondevia, Ramon Charco, Juan Carlos Garcia-Vaidecasas.
{Ger Surgery apd Transplant Unt, IMD, Hospital Cin, Barcotna, Spain.
Introduction: The main pro in LDLT progam isthe donors soley. Never:
tholes, the right hepatectomy is. procedure which comes along wih certain
associted morbidity as well as moray.
‘Aim: To compare the morbdy-moraliy associated with right hepatectomies
In LOLT program with those performed fo Iver dena
Materials and Methods: Prospective data rom 41 donors inthe LDLT pro-
‘fam since Maren 2000 to September 2004 were compared with reospectve
{eta taken rom 41 patnis in which aeght hepaletory was cried out fr LD
liom February 1995 to October 2004. Demographic dat, invaopeai var
‘bles, and postoperative Iver lncton tests were assessed. The movbidly was
‘analzed according othe verl complications associated wih the surgery a5
walla nen-eurgial compieatons.
Fleuita: 17700 wore man and 24/11 were wemen in the LDILDET group re
spectively. Mean age was older in te LD group. There wore no difeences
‘elated tothe need of blood transfusion, and Pesta ly. traopeatve blood
loss was greater in the LD group (p-0,05) The peak of ansarinases was
(eater ine LDLTn pie of phosphelase shale and GGT which reached &
Superior level in LD group (p= 0.03). Pallet coun and coagulation tine eloed
lpmore qucky in LOLT petenia. The idence of overall eomplicaens, o-
gether wih those rotated to surgery was les in tho LDLT group (p>0,0).
Foctoporativo mortality was 0% (LDLT) and 2.4% (LD).
‘Conclusion: The:neidenee of pastopratve complications ater liver resection
Inthe donors similar to tet observes ar an elective major ver surgery.
PO-720] PORTAL 81000 FLOW DIVERSION PRESERVE THE
INTEGRITY OF NON-PARENCHYMAL CELL LINES AND DO
NOT IMPAIR REGENERATION OF SMALL GRAFTS IN
‘ADULT LIVING DONOR LIVER TRANSPLANTATION
‘oberto Tosi, Sahatore Rlocard!', Petr Smeets?, Mareen Pract,
‘Bernard de Hempinne’, ‘Hepate-ilary and Liver Tanspiantaton Service,
‘Ghent Universy Hosptal Medical Schoo “Radiology “Anatomopanoiogy
Introduction: ExcocsWo portal portusion is one ofthe main factors leading
to the smalforsize syndrome (SFSS). In tne study we assess rogenare
ton rates and structural integrity of small gts with hemi-pontcaval shunt
(Pcs),
Methods: From Jue 2002 to November 2004, 10 out of 85 cients under
‘went LDCT with smal ais and MPCS. The moan GREW was of 0.70.1
{tango 0.56.08). Mean recplent ago was o 85.5 Donor rat CT velumey
was dono bolo LOLT and att and 6 m aflor Safal Biopsies were takon bo
{woon 1 and 4 wooks post LDLT, Results were compared toa sores ofS eal
gts ransplanted without poral fow dverson. Semiquanbiatve analysis was
‘one for HE, reeuin (RET), CDSS and smooth muscle ect (SMA) slanngs
‘end compared to biopsies Laken rom 5 oer sme gas Waneplated winout
HPS,
Results: One- and si month post ransplantaion grat volumelstandard ver
volume rato was of 80%. and 101% in shunlod gala and 72% and 70.5% in
PCS showing mocertestutural aggresslon. No SFSS occured in shurtet
gate
Conclusions: Portal blood tow dvorsion prove tho structural integrity of
non epthetal cele ine evoding grat estuncion, HPCS do not impar post
operatve gat cogeneration. The impact of SFSS mey bo led use tis
technique