almately were reteanspanted snd four survived (80%). Ble dot complications developed in $ of organs that survived longer than I year: 2 were managed by perculaneous Satation and stating, and 3 ultimately rquied rensplant for Invabepatc ble duct scares. ‘CONCLUSION: Urgent artrilrevatculrzaon can salvage transplanted vers ‘hemajory ofeses when HAT sdagnosd euly Revansplantation may be necessary ‘ven gras are saccesilyrevoscalarized, bt patent srl in these ass ti ‘toll. The overall paint survival in auacesrulyrevarculrized grafts juss this approtc, Abstract# 289 EFFECTS OF HEPATIC PORTOENTEROSTOMY ON LIVE. DONOR LIVER TRANSPLANTATION FOR THE PEDIATRIC PATIENTS WITH BILIARY ATRESIA. Hideo Kawarasak,' Koichi “Mizuta,” Shuji Hishikawa,' Soshi Takahashi," Yoshiaki Yasuda? Koichi Sugimoto? Koichi Sakamoto.‘ ‘Division of Transplant Surgery, Jichi Medical School, Yakushiji, Minamikawachi-Machi, Kawachi-gun, Tochigi, Japan; ‘Division of Gastroenterogical Surgery, Jichi Medical School, Yakushiji, Minamikawachi-Machi, Kawachi-gun, Tochigi, Japan; *Center for Clinical Pharmacology and Therapeutics, Jichi Medical School, Yakushiji, Minamikawachi-Machi, Kawachi-gun, Tochigi, Japan; ‘Pharmacy, Jichi Medical School, Yakushiji, Minamikawachi-Machi, Kewachl-gun, Tochigi, Japan, ‘Purpose: Elects of hepatic poroenteroimy (HE) on ve donor ver ransplatton LDLT ofthe pian patents with biliary asia was iavesigtd, Patents and ‘methods: Between May 2001 an Februar 2005, LDLT was perfomedin 6 psi tients at urination. ify oe paints wih biliary sresia oto 6S were analyzed, ‘They were divided nto thre grops acordng tothe numberof previous hep porcenterostemyO (group 0, 3) once (grup I n=38) and twice or me (r00p 2, ‘=10), Volume of boot loss during the operat body weight (rg), duran of ‘be opration(min) and morality were investigated between tee gros. Reals: Duran ofthe operation wa sigsfcaly longer ingroup 2th in gronp 1 (0.029) but no significant ference was observed between group O and group 1, The blood Jos tended tobe greater ingroup O than in group I and no significa ference was observed betweeb group 1-and group 2 Mortality was not significantly diferent becween thre groops. Concluslons: From ou surpicl resus, sifu o find dlsadvanages in mull previous HPE exept ong dso ofthe operation fr the Palen with ili atresia at LDLT, Abstract# 290 LIVER TUMORS, TRANSPLANTATION AND FOLLOW-UP IN CHILDREN. Caria Venturi, Eduardo Mullen, Gustavo Boldrini, Eduardo 4d Santbaties, Guillermo Gallo, Daniel D'Agostino, Gastroenterology- Hepatology and Liver Transplantation Division, Pediatric Deparment, Hospital Iraliano, Ciudad Autonoma de Buenos Aires, Argentina, (ntopi Liver anplnation harbecamea welled mol te teament of previa fatal seas in children. Chronic iver dear represents fee pound forthe development of dsplasc nodule and Hepaeclsie earcinomaHHCC), ‘Am: To stud the prevalence of tumor or cella dysplasia in the ede poplin presenting with chronic hepatic disease and the ollow-op evaluation after liver ‘wansplantatcn ‘Method: From a population of 197 Hiver transplants, 137 paiet were stale for presence of liver tumors or cellar dyplasie. Children pretented with flmnant ‘hepatica (25) rezanspan cases (18), well the histologies performed ouside ‘eboepial 2) were exclded, Abdominal ulesscand(US) and verom siphon Inndbeea perforned tthe me of agnosis CT sean was perfomnes inpatients wilh US ost fr ivr mass; mean age at surgery: 36m. (5-208). The pent were divide Im 4 groups depending upon the iver pathology ‘Gro I: Biliary Artesia 49,65 ‘Group I: Cinis du wo infectious, sucimmune or iopabic hepa 25.5%, ‘Grp I: Cinhosis due to meubolic disease 14.65% {Group IV: Miscelaneous 58% Results: 19 patents presented: 8 primary liver neoplasm (6 HCC, hepstobasomas, and i cellar dysplasia, corespondig Group 1 4.4% (Group: 14256 ‘Gro Il: 55 * P<0.0001,0 R: 13.88 (C195% 38.358) Grp 255 1S of 19 patients wansplaaton was inated for neoplasm and cos, ia dhe ‘emaiaing 14, tumor detection was incidesal after hepatectomy. ‘Allien wih one exception 98.7% areal. No erence lignan uasforaton ‘vas observed daring the follow-ap period afr tapant(78.9 mi 2-12). ‘Conclusion: Liver tesa cellular dsplasis showed high prevalace in chon liver disease. Metabolic chasis compared to cinoses of oer crigins showed & strong lnk to tumor and cellar dysplasias. Liver wanplamtation was soccesfol ‘weameat in this population. 113 Abstract# 291 GROWTH PATTERNS IN PEDIATRIC LIVER TRANSPLANT RECIPIENTS BEFORE & AFTER TRANSPLANTATION. Ali Razmkon, Reza Asadollahi, Alireza Mehdizadeh, Afsoon Fazelzadeh, Mobammad-Hossein Anbardar, Mohammad-Hadi_ Imanieh, Heshmatollah Salahi, Seyed-Ali Malek-Hosseini, Shiraz Organ Transplant Center, Shiraz Medical School, Shiraz, Islamic Republic of ran, ‘Alm: In his revospestive analysis we evaluated the re and post-transplant growth of 82 pela iver eansplant recipients fom 199210 2002, n Shiez Organ Transplant, Center ‘Methods: All cases were frst transplants, with the same team and the same immanosoppressve protocol Linear Reght and growth Velocity SD scores were correlated to ap, sx, indication for ransplantaion and graf type. ‘Resuls: Growth retardation was common 98%) especially tn cen older thay 1. Recipients ged younger tan 24 months showed growth within the fst yar achieve ‘belt cstbuton equal to that of tn age-matched populaen.Poetransplanton ‘owt did not comelate with eight standard score at trnsphnation. Chien older tan 2 years at wansplanaion estublished new growth curves, but remned growth retarded, Growth etarstin in ecipints with bili stress was lee common han ‘her repens and also showed increased grow performance ater arsplatation compared to those who underwent tansplantton for oher ests, Both boys and fils were growth eared at wansplamtation with wo significant ference, ba boys Showed improved postansplantion growth perfomance. No carelition to graft ‘ype was ented CConcusion: Early transplantation of citen who show grow retro is optima for restoration of growth potential and daaying vansplantation in older children impedes pote growth Abstracti 292 PAEDIATRIC AUTOIMMUNE LIVER DISEASE: INDICATIONS AND OUTCOME OF LIVER TRANSPLANTATION. Pei Fan Chai,’ Rachel M, Brown. Jo L. MePartland,* Katharine Foster,’ Paul Davies Patrick J. Mekiernan,' Deirdre A. Kelly. ‘Liver Unit, Birmingham Children’s Hospital, Birmingham, West Midlands, United Kingdom; "Pathology Department, Birmingham Children's Hospital, Birmingham, West Midlands, United Kingdom: ‘Radiology Department, Birmingham Children's Hospital, Birmingham, West Midlands, United Kingdom; ‘Statistical Advisory Department, Birmingham Children's Hospital, Birmingham, West Midlands, United Kingdom. Auiomemene liver dseaseCAILD includes sclerosing choltghi(SC),sstoimmane Iepaits type 1 & 2(AIHTIAAIHT2)and oveap syadsome(05) Ale: To review Indications and ostcome of liver transplant (LT) in pediatric AILD. Methods ‘Retrospective review of ll pedi AILD pesening fom 1981-2004 Real 101 tints had confmesd AILD, (60P) 67 had ALT, [8 AIHT2,8 SC and 805. Medan age at disease onset was 11.9 yrscangel.2-18). 98/101 were treated with [redisolonetPNL) and azathioprine AZ), AMT! am seo. Fla ie weamenUPYAFK) GI nom User eats : 5 oot Mecian age at wanplat was 43 yrange. 7 to 21.1 chil with AIH ad 3 with ‘ATHT2 ad emerge LT. Medan tie fom weamentto LT forte ening Lcd ‘was 4 mofrange 8-92). Indcaons foe LT were aut iver flre(s), decompensated Tver disease (12), poor quality of life (and hepaopuloasey syndrome). Main ‘complications pst LT wee billy compen, OT leet) tn pos anelant Jymphoproifeativedieas(). 1 pebeas had 18 epiodes of acute retin snd 2 ad elrone rejection, 5 patents had diease recurence(LAIHTI, SAINT2. IASC), “Median ie from LT to disease recureace was 27 mo(range 16-50, patients Bad ‘repeat (2 chronic ejection, 2 disease recarence) and had ated LThepatie artery thrombosis) Ter were 4 deaths eto sepia), surgery for ulcerative caliis(Dand ddseaserecarence(2). Conlusion Most paediatric AILD respond to medical ten, ‘only a minority require LT. Counselling for LT should indicate the morbidity and ‘motabiy related to paf ejection and dea recumene Abstractt 293 ‘THE NEW PEDIATRIC LIVER TRANSPLANT PROGRAM AT ISMETT, PALERMO. PRELIMINARY EXPERIENCE. Merco Spada, Davide Cintorino, Sivia Riva, Sergio Carzia,’ Maurizio Aricd? Gabriella ‘Traverso,* Bruno Gridelli. ‘Liver Transplantation, ISMETT, Palermo, Italy: "Pediatric Oncology, Ospedale Civico, Palermo, Italy; ‘Pediatrics, Ospedale Civico, Palermo, Italy. Etemsive use of split iver tansplanation SLTx allowed northern Kian transplant Centers to tansplant al the cre in need, withot waiting xt morality A policy Of SLTx has been recently adopted nationwide, allowing to stat a peda ver transplant program inthe soth fay