In this VETgirl online veterinary continuing education podcast, we review canine anaphylaxis. What do the signs of severe canine anaphylaxis look like, and what is the mortality? Is the prognosis good? In this study, 85.1% of dogs survived. Coagulopathy, gallbladder wall edema, and abdominal effusions are a relatively common occurrence in canine anaphylaxis. Serum phosphorus levels greater than 12 mg/dL, refractory hypoglycemia, and PT prolongation greater than 50% are correlated with a decreased chance of survival.