This audio program discusses treatment of postpartum psychosis; predictors of suicidal events among depressed adolescents receiving antidepressant treatment after an unsuccessful trial of an SSRI; whether clinicians can recognize DSM-IV personality disorders from case descriptions based on the Five-Factor Model of personality; a genome-wide scan of families with Mexican or Central American ancestry that identified two new loci likely to harbor genes that carry a predisposition for schizophrenia and schizoaffective disorder; the isolation of a risk allele associated with schizophrenia; and the relationship between neural habituation in the amygdala and social impairments in autism spectrum disorders. Articles can be viewed online at www.ajp.psychiatryonline.org.