SHR # 1583 :: Sarcopenic Obesity, Physical Performance, Disability, and Quality of Life + Short-term Use of Hormone Replacement Therapy Associated with Increased Ovarian Cancer Risk :: Guest: Dr. Lorenzo Donini - Dr. Richard Peto :: Dr. Donini discusses the role that diminishing muscle mass plays in the development of various diseases including depression. This is not just about people who are clearly obese. Even the classic skinny-fat person needs to pay attention to this message. PLUS While Dr. Peto is a statistician and was unable to discuss some of the information I wanted to discuss, his message is very clear. The mainstream media ran away with this headline in an effort to scare women off of HRT. When we dive into the details it seems a lot less alarming.