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How Deep Sleep May Help The Brain Clear Alzheimer's Toxins

A study of 11 sleeping brains sheds some light on the mysterious link between sleep problems and Alzheimer's disease. The flow of cerebrospinal fluid through the brain appears to be the key.
During deep sleep, waves of cerebrospinal fluid (blue) coincide with temporary decreases in blood flow (red). Less blood in the brain means more room for the fluid to carry away toxins, including those associated with Alzheimer's disease.

The brain waves generated during deep sleep appear to trigger a cleaning system in the brain that protects it against Alzheimer's and other neurodegenerative diseases.

Electrical signals known as slow waves appear just before a pulse of fluid washes through the brain, presumably removing toxins associated with Alzheimer's, researchers reported Thursday in the journal Science.

The finding could help explain a puzzling link between sleep and Alzheimer's, says , an author of the study

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