Interstitial Cystitis, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions
By Kenneth Kee
()
About this ebook
This book describes Interstitial Cystitis, Diagnosis and Treatment and Related Diseases
Interstitial cystitis (IC) is often called the painful bladder syndrome.
It is difficult to diagnose and there is no cure though treatments can make life better with it.
If the patient has urinary pain that persists for more than 6 weeks and is not caused by other disorders like infection or kidney stones, the patient may have IC.
The disease can affect the social life, exercise, sleep and even the ability to work.
IC is a chronic bladder disorder.
The bladder retains urine after the kidneys have filtered it but before the patient passes it out.
This disorder induces pain and pressure below the abdominal navel.
Symptoms can come and go.
Or they may be constant.
The patient may have to urinate as many as 40-60 times a day in severe cases.
It can even cause the patient to stay awake at night.
1.Bladder pressure and pain that becomes worse as the bladder fills up.
2.Pain in the lower abdomen, lower back, pelvis, or urethra (the tube that carries urine from the bladder out of the body)
3.For women, pain in the vulva, vagina, or the region behind the vagina
4.For men, pain in the scrotum, testicles, penis, or the region behind the scrotum
5.The necessity to urinate often (more than the normal 7-8 times daily)
All people with it have an inflamed bladder.
About 5% to 10% of people have ulcers in their bladder
Men and women have pain during sex.
About 90% of people with IC are women.
There is an estimate that about 3% to 6% of adult women have some type of IC.
That is about 3 million to 8 million American women.
About 1.3% of American men also have it
On average, people first begin having urinary problems in their 40s.
The risk of having IC goes up as the patient becomes older
Causes:
1.A disorder with bladder tissue allows things in the urine to irritate the bladder.
2.Inflammation induces the body to release chemicals that produce symptoms.
3.Something in the urine injures the bladder.
4.A nerve disorder makes the bladder feel pain from things that normally do not hurt.
5.The immune system cells attacks the bladder cells (autoimmune reaction).
6.Another disorder that causes inflammation somewhere else is also targeting the bladder.
Diagnosis:
There is no specific test for interstitial cystitis
These tests can exclude other disorders:
Urinalysis and urine culture
Post-void residual urine volume
Cystoscopy
Bladder and urethra biopsy
Treatment:
The main treatments for IC are outlined in the AUA IC guideline:
1.First-Line Treatment
a.Self-help
2.Second-Line Treatment
a.Physical Therapy is very important
b.Complementary and Alternative Therapy
c.Oral Medications (e.g. Elmiron)
d.Bladder Instillation
3.Third-Line Treatment
a.Cystoscopy with hydrodistention
4.Fourth-Line Treatment
a.Neurostimulation
5.Fifth-Line Treatment
a.Immunosuppressants (e.g. Cyclosporine)
b.Botox
6.Sixth-Line Treatment
a.Surgery
Updated treatment
Doctors think of the first line of treatment as the typical one.
1. Pentosan polysulfate
2. Hydroxyzine
A defective layer coating the bladder lining (glycosaminoglycan) in IC caused testing of the Elmiron to replace the layer.
The mast cell proliferation and swelling in the bladder wall observed in IC also appeared like an allergic reaction, so doctors began to try antihistamines, such as hydroxyzine (Atarax).
Some autoimmune diseases are more frequent in IC patients
The idea triggered medical uses of immunosuppressive drugs
One useful IC treatment is amitriptyline, a tricyclic antidepressant which can also relieve pain
A new treatment is based on liposomes, microscopic particles that can dissolve fat for bladder instillation
TABLE OF CONTENT
Introdu
Kenneth Kee
Medical doctor since 1972.Started Kee Clinic in 1974 at 15 Holland Dr #03-102, relocated to 36 Holland Dr #01-10 in 2009.Did my M.Sc (Health Management ) in 1991 and Ph.D (Healthcare Administration) in 1993.Dr Kenneth Kee is still working as a family doctor at the age of 74However he has reduced his consultation hours to 3 hours in the morning and 2 hours inthe afternoon.He first started writing free blogs on medical disorders seen in the clinic in 2007 on http://kennethkee.blogspot.com.His purpose in writing these simple guides was for the health education of his patients which is also his dissertation for his Ph.D (Healthcare Administration). He then wrote an autobiography account of his journey as a medical student to family doctor on his other blog http://afamilydoctorstale.blogspot.comThis autobiography account “A Family Doctor’s Tale” was combined with his early “A Simple Guide to Medical Disorders” into a new Wordpress Blog “A Family Doctor’s Tale” on http://ken-med.com.From which many free articles from the blog was taken and put together into 1000 eBooks.He apologized for typos and spelling mistakes in his earlier books.He will endeavor to improve the writing in futures.Some people have complained that the simple guides are too simple.For their information they are made simple in order to educate the patients.The later books go into more details of medical disorders.He has published 1000 eBooks on various subjects on health, 1 autobiography of his medical journey, another on the autobiography of a Cancer survivor, 2 children stories and one how to study for his nephew and grand-daughter.The purpose of these simple guides is to educate patient on health disorders and not meant as textbooks.He does not do any night duty since 2000 ever since Dr Tan had his second stroke.His clinic is now relocated to the Buona Vista Community Centre.The 2 units of his original clinic are being demolished to make way for a new Shopping Mall.He is now doing some blogging and internet surfing (bulletin boards since the 1980's) startingwith the Apple computer and going to PC.The entire PC is upgraded by himself from XT to the present Pentium duo core.The present Intel i7 CPU is out of reach at the moment because the CPU is still expensive.He is also into DIY changing his own toilet cistern and other electric appliance.His hunger for knowledge has not abated and he is a lifelong learner.The children have all grown up and there are 2 grandchildren who are even more technically advanced than the grandfather where mobile phones are concerned.This book is taken from some of the many articles in his blog (now with 740 posts) A Family Doctor’s Tale.Dr Kee is the author of:"A Family Doctor's Tale""Life Lessons Learned From The Study And Practice Of Medicine""Case Notes From A Family Doctor"
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Interstitial Cystitis, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions - Kenneth Kee
Interstitial Cystitis,
A
Simple
Guide
To
The Condition,
Diagnosis,
Treatment
And
Related Conditions
By
Dr Kenneth Kee
M.B.,B.S. (Singapore)
Ph.D (Healthcare Administration)
Copyright Kenneth Kee 2019 Smashwords Edition
Published by Kenneth Kee at Smashwords.com
Dedication
This book is dedicated
To my wife Dorothy
And my children
Carolyn, Grace
And Kelvin
This book describes Interstitial Cystitis, Diagnosis and Treatment and Related Diseases which is seen in some of my patients in my Family Clinic.
(What You Need to Treat Interstitial Cystitis)
This eBook is licensed for your personal enjoyment only. This eBook may not be re-sold or given away to other people. If you would like to share this book with another person, please purchase an additional copy for each reader.
If you’re reading this book and did not purchase it, or it was not purchased for your use only, then please return to Smashwords.com and purchase your own copy.
Thank you for respecting the hard work of this author.
Introduction
I have been writing medical articles for my blog: http://kennethkee.blogspot.com (A Simple Guide to Medical Disorder) for the benefit of my patients since 2007.
My purpose in writing these simple guides was for the health education of my patients.
Health Education was also my dissertation for my Ph.D (Healthcare Administration).
I then wrote an autobiolographical account of his journey as a medical student to family doctor on his other blog: http://afamilydoctorstale.blogspot.com.
This autobiolographical account A Family Doctor’s Tale
was combined with my early A Simple Guide to Medical Disorders
into a new Wordpress Blog A Family Doctor’s Tale
on http://kenkee481.wordpress.com.
From which many free articles from the blog was taken and put together into 800 eBooks.
Some people have complained that the simple guides are too simple.
For their information they are made simple in order to educate the patients.
The later books go into more details of medical disorders.
The first chapter is always from my earlier blogs which unfortunately tends to have typos and spelling mistakes.
Since 2013, I have tried to improve my spelling and writing.
As I tried to bring the patient the latest information about a disorder or illness by reading the latest journals both online and offline, I find that I am learning more and improving on my own medical knowledge in diagnosis and treatment for my patients.
Just by writing all these simple guides I find that I have learned a lot from your reviews (good or bad), criticism and advice.
I am sorry for the repetitions in these simple guides as the second chapters onwards have new information as compared to my first chapter taken from my blog.
I also find repetition definitely help me and maybe some readers to remember the facts in the books more easily.
I apologize if these repetitions are irritating to some readers.
Chapter 1
Interstitial Cystitis
What Is Interstitial Cystitis?
Interstitial cystitis (IC) is often called the painful bladder syndrome.
It is difficult to diagnose and there is no cure though treatments can make life better with it.
If the patient has urinary pain that persists for more than 6 weeks and is not caused by other disorders like infection or kidney stones, the patient may have IC.
The disease can influence the social life, exercise, sleep and even the ability to work.
IC is a chronic bladder disorder.
The bladder retains urine after the kidneys have filtered it but before the patient passes it out.
This disorder induces pain and pressure below the abdominal navel.
Symptoms can come and go.
Or they may be constant.
Interstitial cystitis produces urgent, often painful bathroom trips.
The patient may have to urinate as many as 40-60 times a day in severe cases.
It can even cause the patient to stay awake at night.
What Are the Symptoms of Interstitial cystitis?
These differ from person to person with IC.
They can vary every day or week or persist for months or years.
They might even disappear without any treatment.
Frequent symptoms:
1. Bladder pressure and pain that becomes worse as the bladder fills up.
2. Pain in the lower abdomen, lower back, pelvis, or urethra (the tube that carries urine from the bladder out of the body)
3. For women, pain in the vulva, vagina, or the region behind the vagina
4. For men, pain in the scrotum, testicles, penis, or the