Skeletal Muscle Cell, Functions, Diseases, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions
By Kenneth Kee
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About this ebook
This book describes Skeletal Muscle Cell, Functions, Diseases, Diagnosis and Treatment and Related Diseases
A myocyte (muscle cell) is the type of cell present in muscle tissue.
They are long, tubular cells that originate developmentally from myoblasts to form muscles.
Muscle tissues originate from the mesodermal layer of embryonic germ cells.
There are specialized types of myocytes:
1.Skeletal muscle cells
2.Cardiac muscle cells
3.Smooth muscle cells
Cardiac myocytes are accountable for producing the electrical impulses that regulate the heart rate, among other functions.
A myoblast is a form of embryonic progenitor cell that separates to produce muscle cells.
Skeletal muscle fibers are produced when myoblasts join together.
Skeletal Muscle fibers thus have multiple nuclei (each nucleus coming from a single myoblast).
The combination of myoblasts is specific to skeletal muscle (e.g., biceps brachii) and not cardiac muscle or smooth muscle.
Skeletal Muscle cells have protein filaments that slide past one another producing a contraction that alters both the length and the shape of the cell.
Skeletal Muscles work to produce force and motion.
Life and Death of Skeletal Muscle Cell
My name is Muscle Man the skeletal muscle cell.
I was named Muscle Man by my friends who feel that I am very strong.
I was born in the body from a stem cell from the myotome during the development of the embryo.
During development, myoblasts (the muscle progenitor cells) either remain in the somite to form muscles linked with the vertebral column or migrate out into the body to form all other muscles.
Most of us migrate by following chemical signals to the proper locations where we fuse into elongate skeletal muscle cells.
Each of us is made up of cell which is surrounded by a cell membrane called the sarcolemma.
Beneath the membrane are found a large number of nuclei
I am called a structural syncythium which is a multinucleate cell which is the result from multiple cell fusions of uninuclear cells.
A muscle fiber forming part of a muscle may vary in length from 1 mm to 30cm in length.
Each of us is striated.
We consist of a number of parallel myofilaments showing light and dark bands.
The A band contains protein containing myosin while the T band contains the protein actin.
When I contract, my Actin filament actually slides across my T filament.
This movement can shorten my body to half of its length
The contraction of my body is brought about by the impulses from the motor neuron fiber which made contact with me at the myoneural junctions or motor end plates.
My nerve fiber supplies as many of 200 of us, meaning that it is a large motor unit.
When my muscle contracts to flex the forearm, the relaxation of the triceps muscles at the back of the upper arm produces a smooth contraction of the biceps (synergy of muscle).
When I contract, in addition to the proteins actin and myosin, I also need calcium, magnesium. ATP and ATPase
We muscles are mainly powered by the oxidation of fats and carbohydrates.
Anaerobic chemical reactions are also used mainly by fast twitch fibers.
Energy for my muscle contraction is supplied by the high energy ATP
We muscles conserve energy in the form of creatine phosphate which is produced from ATP and can regenerate ATP with creatine kinase.
We also keep a storage form of glucose in the form of glycogen.
Once the nerve cell is killed or dies from old age, my muscle cell is also affected and I will atrophy and die slowly.
We muscle cells are very healthy and live for a long time.
Fast death of a muscle cell is by necrosis through damage to my cell.
If no regeneration is possible then my cell will die rapidly.
TABLE OF CONTENT
Introduction
Chapter 1 Skeletal Muscle Cell
Chapter 2 Functions
Chapter 3 Life Cycle
Chapter 4 Diseases
Ch
Kenneth Kee
Medical doctor since 1972.Started Kee Clinic in 1974 at 15 Holland Dr #03-102, relocated to 36 Holland Dr #01-10 in 2009.Did my M.Sc (Health Management ) in 1991 and Ph.D (Healthcare Administration) in 1993.Dr Kenneth Kee is still working as a family doctor at the age of 74However he has reduced his consultation hours to 3 hours in the morning and 2 hours inthe afternoon.He first started writing free blogs on medical disorders seen in the clinic in 2007 on http://kennethkee.blogspot.com.His purpose in writing these simple guides was for the health education of his patients which is also his dissertation for his Ph.D (Healthcare Administration). He then wrote an autobiography account of his journey as a medical student to family doctor on his other blog http://afamilydoctorstale.blogspot.comThis autobiography account “A Family Doctor’s Tale” was combined with his early “A Simple Guide to Medical Disorders” into a new Wordpress Blog “A Family Doctor’s Tale” on http://ken-med.com.From which many free articles from the blog was taken and put together into 1000 eBooks.He apologized for typos and spelling mistakes in his earlier books.He will endeavor to improve the writing in futures.Some people have complained that the simple guides are too simple.For their information they are made simple in order to educate the patients.The later books go into more details of medical disorders.He has published 1000 eBooks on various subjects on health, 1 autobiography of his medical journey, another on the autobiography of a Cancer survivor, 2 children stories and one how to study for his nephew and grand-daughter.The purpose of these simple guides is to educate patient on health disorders and not meant as textbooks.He does not do any night duty since 2000 ever since Dr Tan had his second stroke.His clinic is now relocated to the Buona Vista Community Centre.The 2 units of his original clinic are being demolished to make way for a new Shopping Mall.He is now doing some blogging and internet surfing (bulletin boards since the 1980's) startingwith the Apple computer and going to PC.The entire PC is upgraded by himself from XT to the present Pentium duo core.The present Intel i7 CPU is out of reach at the moment because the CPU is still expensive.He is also into DIY changing his own toilet cistern and other electric appliance.His hunger for knowledge has not abated and he is a lifelong learner.The children have all grown up and there are 2 grandchildren who are even more technically advanced than the grandfather where mobile phones are concerned.This book is taken from some of the many articles in his blog (now with 740 posts) A Family Doctor’s Tale.Dr Kee is the author of:"A Family Doctor's Tale""Life Lessons Learned From The Study And Practice Of Medicine""Case Notes From A Family Doctor"
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