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    A Handbook of Aortoarteritis and Ruptured Sinus of Valsalva
    A Handbook of Aortoarteritis and Ruptured Sinus of Valsalva
    A Handbook of Aortoarteritis and Ruptured Sinus of Valsalva
    Ebook107 pages42 minutes

    A Handbook of Aortoarteritis and Ruptured Sinus of Valsalva

    By Alok Ranjan

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    About this ebook

    A Handbook of Aortoarteritis and Ruptured Sinus of Valsalva contains a detailed description of these diseases. Aortoarteritis is a relatively common disease in Indian subcontinent. It is a common cause of dilated cardiomyopathy in this region. It has various presentations due to stenotic involvement of aorta and its branches. Ruptured sinus of Valsalva although rare but has catastrophic clinical presentation. These diseases require early recognition and diagnosis to optimize management of patients. Current text books lack a detailed description of these diseases. Special efforts have been made by the author to give a thorough overview of these diseases. Clinical features (Symptoms and signs), investigations, natural history, prognosis as well as management have been dealt in details. Clinical features are probably the forgotten art in the newer text books. However, the author has taken a special interest to include a detailed description of clinical features. The treatment section includes description about the various interventions (catheter based as well as surgical). The author has published a series of handbooks on Rheumatic fever and Valvular heart diseases from AuthorHouse. Like his previous books, this book also has extensive description of all aspects of the disease.
    All in all, the book promises to be a great reference book for Aortoarteritis and Ruptured sinus of Valsalva and is worth having it on shelf for easy reading. The point wise and concise writing has made this book useful for students especially exam going students.
    LanguageEnglish
    PublisherAuthorHouse
    Release dateDec 10, 2015
    ISBN9781504963077
    A Handbook of Aortoarteritis and Ruptured Sinus of Valsalva

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      Book preview

      A Handbook of Aortoarteritis and Ruptured Sinus of Valsalva - Alok Ranjan

      © 2015 Alok Ranjan. All rights reserved.

      Illustrations: Dr. Rita K Sinha

      No part of this book may be reproduced, stored in a retrieval system, or transmitted by any means without the written permission of the author.

      Published by AuthorHouse  12/03/2015

      ISBN: 978-1-5049-6309-1 (sc)

      ISBN: 978-1-5049-6308-4 (hc)

      ISBN: 978-1-5049-6307-7 (e)

      Library of Congress Control Number: 2015919429

      Any people depicted in stock imagery provided by Thinkstock are models,

      and such images are being used for illustrative purposes only.

      Certain stock imagery © Thinkstock.

      Because of the dynamic nature of the Internet, any web addresses or links contained in this book may have changed since publication and may no longer be valid. The views expressed in this work are solely those of the author and do not necessarily reflect the views of the publisher, and the publisher hereby disclaims any responsibility for them.

      Index

      Aortoarteritis (AA)

      Definition

      Etiology

      Pathophysiology

      Clinical Manifestation

      Clinical Features: Specific organ involvement

      Indian characteristics of AA

      Classification of Aortoarteritis

      Investigations

      Diagnosis of Aortoarteritis

      Natural history of Aortoarteritis

      Aortoarteritis: Special subsets

      Aortoarteritis: Management

      Aortoarteritis: Important Indian Studies

      Ruptured Sinus of Valsalva (RSOV)

      Anatomy: Sinus of Valsalva (SOV)

      Pathology of Aneurysm of Sinus of Valsalva (ASOV)

      Classification of ASOV

      Incidence of various types of ASOV or RSOVs

      Clinical presentation of sinus of Valsalva aneurysm

      Clinical presentation: Ruptured sinus of Valsalva (RSOV)

      Jugular venous pulse (JVP) in RSOV

      RSOV: Investigations

      Hemodynamics

      Differential Diagnosis

      Management

      Prognosis

      Indian series

      Dedication

      Dedicated to my teachers (Dr. (Mrs.) R. B. Amin, Dr. (Mrs.) S. S. Sirsikar and Dr. A. S. Mane) and friends at Sassoon General Hospital and B J Medical college, Pune, Maharashtra, India

      "One looks back with appreciation to the brilliant teachers, but with gratitude to those who touched our human feelings. The curriculum is so much necessary raw material, but warmth is the vital element for the growing plant and for the soul of the child.’

      Carl Gustav Jung (1875-1961) Swiss psychologist and psychiatrist.

      Aortoarteritis (AA)

      Definition

      AA is a chronic inflammatory disease of unknown etiology that involves aorta and its major branches.

      American College of Rheumatology (1990)

      Modification suggested by Kinare et al

      (Pathology and Radiology. Mumbai, Quest 1998; 69.)

      AA is an idiopathic inflammatory disease of large elastic arteries occurring in the young and resulting in occlusive or ectatic changes mainly in aorta and its immediate branches as well as the pulmonary artery and its branches.

      Synonyms

      Takayasu arteritis (TA)

      Reversed coarctation

      Pulseless disease

      Aortic arch syndrome

      Occlusive thrombo-aortopathy: Coined by Ishikawa

      Describes the basic pathophysiology

      Young female arteritis

      Non-specific aortoarteritis

      Etiology

      Disease of unknown etiology

      Can be best described as triggered by an external stimulus in genetically predisposed subjects

      Most favored theory is autoimmune inflammatory reaction

      Supported by increased levels of immunoglobulins

      Presence of anti aorta antibodies

      Not reported extensively by workers outside Japan

      Reported by Dhingra R, Talwar KK

      Presence of anti endothelial cell antibodies

      Genetic studies

      Association with HLA system

      Kumar et al reported

      An increased frequency of HLA B5 and B21

      Decreased frequency of HLA B 35 and B 40

      Linked to

      Rheumatic fever

      Proposed by Ask – Upmark

      Not valid now

      Tuberculosis

      Reported by Japanese workers

      Supported by Kinare et al from India

      Streptococcal infections

      Rheumatoid arthritis

      Other Collagen vascular disease

      Pathophysiology

      Histopathology:

      Hallmark of the disease is a granulomatous lesion with giant cells.

      Hence classified as ‘giant cell arteritis’

      Phases of histopathological changes:

      Active phase

      Diffuse inflammation: Earliest phase

      Starts at junction of media and adventitia

      Spreads to adventitia and

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