Diabetes Mellitus Type 3c, (Pancreatogenic Diabetes) A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions
By Kenneth Kee
()
About this ebook
This book describes Pancreatogenic Diabetes, Diagnosis and Treatment and Related Diseases
Just a week ago I was emailed an article on Pancreatogenic Diabetes
Intrigued I decided to look further into research papers and found that it is not as rare as it appeared.
Pancreatogenic diabetes is a form of secondary diabetes that occurs when pancreatic inflammation, neoplasia, or resection leads to beta-cell dysfunction, affecting the secretion of insulin causing Types 3c Diabetes.
Type 3c diabetes is almost twice as frequent as type 1 diabetes but is misdiagnosed as type 2 diabetes in over 87% of patients.
Type 3c diabetes patients tended about 1.5 times more likely to have poor glycemic control than those with type 2 diabetes and tended almost 10 times more likely to use insulin.
Those with type 3c diabetes need insulin therapy more urgently than those with type 2, so the result of this misdiagnosis are delays in giving proper treatment leading to nerve, eye, and kidney damage.
Causes:
1.Chronic pancreatitis is the most frequent disease of the exocrine pancreas linked with the development of diabetes
2.Cystic fibrosis-related diabetes (CFRD)
3.Lacking genes in the E2F group
4.Finally, other less frequent forms of pancreatogenic diabetes are present, such as that due to pancreatic cancer, and post-pancreatectomy diabetes
Symptoms:
These symptoms are typical of diabetes:
1. Frequent thirst even after drinking lots of water
2. Passing more frequent urine during day and night
3. Weight loss
Most patients with T3cDM have a known history of:
1. Pancreatitis with abdominal pain,
2. Steatorrhea or
3. Mal-digestion
4. Nutritional deficiencies and
5. Glucose intolerance.
Patients may also manifest with symptoms of:
1. Mal-digestion and
2. Abdominal pain
Diagnosis:
The diagnosis of T3cDM requires
1.The evidence of pancreatic exocrine insufficiency (based on monoclonal fecal elastase 1 test)
2.Evidence of pathological pancreatic imaging (by endoscopic ultrasound, MRI)
3.The absence of type 1 diabetes mellitus (T1DM)-linked auto-antibodies
Confirmation of T3cDM can then be made by report of an absent pancreatic polypeptide response to mixed-nutrient ingestion
Treatment:
The treatment of hyperglycemia to reach and maintain the HbA1c
Kenneth Kee
Medical doctor since 1972.Started Kee Clinic in 1974 at 15 Holland Dr #03-102, relocated to 36 Holland Dr #01-10 in 2009.Did my M.Sc (Health Management ) in 1991 and Ph.D (Healthcare Administration) in 1993.Dr Kenneth Kee is still working as a family doctor at the age of 74However he has reduced his consultation hours to 3 hours in the morning and 2 hours inthe afternoon.He first started writing free blogs on medical disorders seen in the clinic in 2007 on http://kennethkee.blogspot.com.His purpose in writing these simple guides was for the health education of his patients which is also his dissertation for his Ph.D (Healthcare Administration). He then wrote an autobiography account of his journey as a medical student to family doctor on his other blog http://afamilydoctorstale.blogspot.comThis autobiography account “A Family Doctor’s Tale” was combined with his early “A Simple Guide to Medical Disorders” into a new Wordpress Blog “A Family Doctor’s Tale” on http://ken-med.com.From which many free articles from the blog was taken and put together into 1000 eBooks.He apologized for typos and spelling mistakes in his earlier books.He will endeavor to improve the writing in futures.Some people have complained that the simple guides are too simple.For their information they are made simple in order to educate the patients.The later books go into more details of medical disorders.He has published 1000 eBooks on various subjects on health, 1 autobiography of his medical journey, another on the autobiography of a Cancer survivor, 2 children stories and one how to study for his nephew and grand-daughter.The purpose of these simple guides is to educate patient on health disorders and not meant as textbooks.He does not do any night duty since 2000 ever since Dr Tan had his second stroke.His clinic is now relocated to the Buona Vista Community Centre.The 2 units of his original clinic are being demolished to make way for a new Shopping Mall.He is now doing some blogging and internet surfing (bulletin boards since the 1980's) startingwith the Apple computer and going to PC.The entire PC is upgraded by himself from XT to the present Pentium duo core.The present Intel i7 CPU is out of reach at the moment because the CPU is still expensive.He is also into DIY changing his own toilet cistern and other electric appliance.His hunger for knowledge has not abated and he is a lifelong learner.The children have all grown up and there are 2 grandchildren who are even more technically advanced than the grandfather where mobile phones are concerned.This book is taken from some of the many articles in his blog (now with 740 posts) A Family Doctor’s Tale.Dr Kee is the author of:"A Family Doctor's Tale""Life Lessons Learned From The Study And Practice Of Medicine""Case Notes From A Family Doctor"
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Diabetes Mellitus Type 3c, (Pancreatogenic Diabetes) A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions - Kenneth Kee
Diabetes Mellitus Type 3c,
(Pancreatogenic Diabetes)
A
Simple
Guide
To
The Condition,
Diagnosis,
Treatment
And
Related Conditions
By
Dr Kenneth Kee
M.B.,B.S. (Singapore)
Ph.D (Healthcare Administration)
Copyright Kenneth Kee 2017 Smashwords Edition
Published by Kenneth Kee at Smashwords.com
Dedication
This book is dedicated
To my wife Dorothy
And my children
Carolyn, Grace
And Kelvin
This book describes Pancreatogenic Diabetes, Diagnosis and Treatment and Related Diseases which is seen in some of my patients in my Family Clinic.
(What The patient Need to Treat Pancreatogenic Diabetes)
This eBook is licensed for the personal enjoyment only. This eBook may not be re-sold or given away to other people. If you would like to share this book with another person, please purchase an additional copy for each reader.
If you’re reading this book and did not purchase it, or it was not purchased for your use only, then please return to Smashwords.com and purchase your own copy.
Thank you for respecting the hard work of this author.
Introduction
I have been writing medical articles for my blog http://kennethkee.blogspot.com (A Simple Guide to Medical Disorder) for the benefit of my patients since 2007.
My purpose in writing these simple guides was for the health education of my patients.
Health Education was also my dissertation for my Ph.D (Healthcare Administration).
I then wrote an autobiolographical account of his journey as a medical student to family doctor on his other blog http://afamilydoctorstale.blogspot.com.
This autobiolographical account A Family Doctor’s Tale
was combined with my early A Simple Guide to Medical Disorders
into a new Wordpress Blog A Family Doctor’s Tale
on http://kenkee481.wordpress.com.
From which many free articles from the blog was taken and put together into 800 amazon kindle books and 200 into Smashwords.com eBooks.
Some people have complained that the simple guides are too simple.
For their information they are made simple in order to educate the patients.
The later books go into more details of medical disorders.
The first chapter is always from my earlier blogs which unfortunately tends to have typos and spelling mistakes.
Since 2013, I have tried to improve my spelling and writing.
As I tried to bring the patient the latest information about a disorder or illness by reading the latest journals both online and offline, I find that I am learning more and improving on my own medical knowledge in diagnosis and treatment for my patients.
Just by writing all these simple guides I find that I have learned a lot from your reviews (good or bad), criticism and advice.
I am sorry for the repetitions in these simple guides as the second chapters onwards have new information as compared to my first chapter taken from my blog.
I also find repetition definitely help me and maybe some readers to remember the facts in the books more easily.
I apologize if these repetitions are irritating to some readers.
Chapter 1
Diabetes Type 3c (Pancreatogenic Diabetes)
Just a week ago I was emailed an article on Pancreatogenic Diabetes by MIMS Singapore, a new form of Diabetes, also known as Type 3c Diabetes.
Intrigued by this new disease, I decided to look further into research papers and found that it is not as rare as it appeared.
In fact many patients were wrongly diagnosed as Diabetes Mellitus 2.
What is Diabetes Type 3c (Pancreatogenic Diabetes)?
Diabetes Type 3c (Pancreatogenic Diabetes) is a form of secondary diabetes that is specifically linked with disease of the exocrine pancreas.
Patients with a form of diabetes due to pancreatic dysfunction are often misdiagnosed as having type 2 diabetes, resulting in poor glycemic control and suboptimal care.
Diabetes of the exocrine pancreas called type 3c diabetes occurs when pancreatic inflammation, neoplasia, or resection leads to beta-cell dysfunction, affecting the secretion of insulin.
As it occurs in similar age group, type 3c diabetes may be misdiagnosed as type 2 diabetes.
Type 3c diabetes is almost twice as frequent as type 1 diabetes but is wrongly diagnosed as type 2 diabetes in over 87% of patients.
Type 3c diabetes patients tended about 1.5 times more likely to have poor glycemic control than those with type 2 diabetes and tended almost 10 times more likely to use insulin.
Those with type 3c diabetes need insulin therapy more urgently than those with type 2, so the result of this misdiagnosis are delays in giving proper treatment leading to nerve, eye, and kidney damage
More recognition of type 3c diabetes within the medical profession is needed urgently to improve treatment of this disease, which now has a higher incidence than type 1 diabetes in adults.
The wrong diagnosis of type 3c diabetes, mostly as type 2 diabetes, places the short- and long-term health of patients at risk.
What are the causes of Diabetes Type 3c (Pancreatogenic Diabetes)?
Causes:
There are 4 main causes of Type 3c Diabetes Mellitus:
1. Chronic pancreatitis is the most frequent disease of the exocrine pancreas linked with the development of diabetes.
While the distinct pathogenesis of diabetes in chronic pancreatitis has also long been known, only recently guidelines have been developed supporting a specified diagnosis and treatment algorithm.
2. Cystic fibrosis-related diabetes (CFRD) is just like chronic pancreatitis-linked diabetes, in which pancreatic exocrine insufficiency happens before the pancreatic endocrine insufficiency responsible for the development of diabetes.
Because diabetes in cystic fibrosis is linked with worse nutritional status, more severe inflammatory lung disease, and greater mortality from respiratory failure,
CFRD has long been recognized as a distinct form of diabetes requiring a specified approach to evaluation