The Atlantic

The Long Haul of Vaccine Results Is Just Beginning

The initial results of the AstraZeneca/Oxford vaccine trials were unexpected and confusing, but there’s more data to come.
Source: Siphiwe Sibeko / Reuters


The first two coronavirus-vaccine trials ran as smoothly as anyone could hope. And when the results from both Pfizer/BioNTech and Moderna came back with more than 90 percent efficacy, easily surpassing the FDA’s bar of 50 percent, even people like me—who kept telling you to temper your vaccine expectations—reacted with uncharacteristic and unrestrained optimism. These results really were about as good as it gets.

Then came the results for a third vaccine, from AstraZeneca, developed in collaboration with Oxford University. At a glance, these looked good, if not spectacular: an average of . But that top-line result obscured a strange divide between a full, two-shot

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