The Paris Review

One Word: Castration

Anonymous, Non biedt kat vis aan in ruil voor penis (detail), 1555

We defend ourselves not against castration anxiety but against death, a far more absolute castration.

—Ernest Becker, The Denial of Death

The university library at my medical school was shared with students of veterinary medicine. Sometimes I’d find myself at a desk opposite one of the vet students; we’d glance at one another’s textbooks with curiosity, occasionally open at the same subjects—hematology, say, or orthopedic surgery. It was reassuring to see how much common ground there was between medicine for humans and medicine for animals.

One day, I was revising prostate cancer: the appearance of its malignant cells under a microscope, the stages of its spread, the radiotherapy, brachytherapy (embedding of radioactive pellets into the tumor), and standard chemotherapies used to treat it. In health, the prostate gland stores semen and mature sperm; it has strong muscular walls that squeeze during ejaculation. Exposure to a lifetime of testosterone increases the growth of the gland as well as its susceptibility to cancers. Many treatments for prostate cancer work by blocking testosterone’s generation within the testicles—with no testosterone, the growth of the tumor slows.

“All that

You’re reading a preview, subscribe to read more.

More from The Paris Review

The Paris Review19 min read
The Beautiful Salmon
I’ve always loved salmon. Not to eat, as I don’t eat fish, but I’ve always loved salmon in general because salmon jump and no one knows why. They jump all over the place—out of rivers, up waterfalls. Some say they jump to clean their gills. Others sa
The Paris Review1 min read
The People’s History of 1998
France won the World Cup.Our dark-goggled dictator died from eating a poisoned red applethough everyone knew it was the CIA. We lived miles from the Atlantic.We watched Dr. Dolittle, Titanic, The Mask of Zorro. Our grandfather, purblind and waitingfo
The Paris Review32 min read
The Art of Fiction No. 262
My first conversations with Jhumpa Lahiri took place in Rome this past July, in her apartment near the Janiculum, above Trastevere. It was an extremely hot summer—one of our meetings was on the hottest day in Rome’s history, 110 degrees—and we sat wi

Related Books & Audiobooks