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AV bundle: passes through hole in cardiac C.T. skeleton to reach interventricular septum Right and left bundle branches: extend beneath endocardium to apices of right and left ventricles Purkinje fibers:
Large diameter cardiac muscle cells with few myofibrils. Many gap junctions. Conduct action potential to ventricular muscle cells (myocardium) very rapidly
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Na+ Leak
2 Seconds
June 4, 2012
AV Node, and Delay of Impulse Conduction from the Atria to the Ventricles
Location of the A-V node: in the posterior wall of the right atrium immediately behind the tricuspid valve there is a delay of 0.09 second in the A-V node A delay of another 0.04 second occurs mainly in A-V bundle Thus, the total delay in the A-V nodal and A-V bundle system is about 0.13 second.
AV Node, and Delay of Impulse Conduction from the Atria to the Ventricles
Cause of the Slow Conduction: caused mainly by diminished numbers of gap junctions b/w successive cells in the conducting pathways Importance of AV nodal delay: this delay allows time for the atria to empty their blood into the ventricles before ventricular contraction begins One-Way Conduction Through the A-V Bundle?
Conduction velocities of heart tissues: ATRIAL MUSCLE= 0.3m/sec INTERNODAL PATHWAYS= 1m/sec AV NODE: slowest 0.050.1m/sec AV BUNDLE & BRANCHES/PURKINJE SYSTEM: Maximum velocity= 1.54m/sec VENTRICULAR MUSCLE= 0.5m/sec
June 4, 2012
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June 4, 2012
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June 4, 2012