Documenti di Didattica
Documenti di Professioni
Documenti di Cultura
Martini
Fundamentals of
Blood travels from efferent arteriole to peritubular capillaries Vasa recta Renal tubule begins at renal corpuscle Includes glomerulus and Bowmans capsule
Glomerulus anatomy
Podocytes cover lamina densa of capillaries Project into the capsular space
Figure 26.8a, b
Figure 26.8c, d
Descending limb
Ascending limb Each limb has a thick and thin section
PLAY
Distal convoluted tubule (DCT) Actively secretes ions, toxins, drugs Reabsorbs sodium ions from tubular fluid
PLAY
Urea
Creatinine Uric acid
Blood pressure
Water and solutes across glomerular capillaries
Reabsorption
The removal of water and solutes from the filtrate
Secretion
Transport of solutes from the peritubular fluid into the tubular fluid
Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Facilitated diffusion
Active transport Cotransport Countertransport Carrier proteins have a transport maximum (Tm)
Renal function
Most regions of the nephron perform a combination of functions
Figure 26.9
Figure 26.10
Figure 26.10a, b
Amount of filtrate produced in the kidneys each minute Factors that alter filtration pressure change GFR
A drop in filtration pressure stimulates Juxtaglomerular apparatus (JGA) Releases renin and erythropoietin
Figure 26.11a
Figure 26.11b
Sympathetic activation
Produces powerful vasoconstriction of afferent arterioles Decreases GFR and slows production of filtrate Changes the regional pattern of blood flow Alters GFR Stimulates release of renin by JGA