Viral Lesions Oral Patho

VIRAL LESIONS
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DNA VIRUS:1) HERPES GROUP :Herpes Simplex Herpes Zoster/ Variecella Cytomegalic Virus Epstein Barr- Virus- Infective Mononucleasis a) Herpes Simplex Consists prin. of the skin, Mucous membrane, eyes & Central Nervous System. TYPES:HSVI above the waist i.e. upper part of body. Face, lips, oral cavity, etc. HSVII below the waist i.e. lower part of body. Genitals & Skin of lower body.
ORAL INFECTIONS
PRIMARY Infection
Without circulating
RECURENT Infection
Circulating antibodies
antibodies
are already present.
1. Primary HS infection Also k/a * Acute Herpetic Gingivostomatitis. * Herpetic Labialis * Fever Blisters * Cold Sore * Infectious Stomatitis
CLINICAL FEATURES :-
Most Common in older adults Does Not affect the child below 6 months of age because of circulating antibodies. SYMPTOMS:Regional lymphadenopathy, headache, malaise, nausea, vomiting, pain upon swallowing. SITE:Lip, tongue, buccal mucosa, tonsils & pharynx may be involved. Oral Cavity becomes erythematous Yellowish , fluid filled vesicles develop Rupture www.rxdentistry.blogspot.com
Painful ulcers covered by a grey membrane and surrounded by erythematous halo. Vary 2- 6mm in size. Heals spontaneously within 7 to 10 days. No Scar Usual Ganglion involved in HSV-I TRIGEMINAL Usual Ganglion involved in HSV-II LUMBOSACRAL
HISTOPATHOLOGY Intraepithelial blister and ballooning degeneration Intranuclear inclusions LIPSCHUTZ BODIES.
2. Recurrent or Secondary Herpetic Infection:CLINICAL FEATURES:TYPES: Recurrent herpes labialis (RHL) Recurrent intraoral herpes simplex infection (RIM). Occurs in a month www.rxdentistry.blogspot.com a year. to only about once
H/F:-
SYMPTOMS:Tingling & burning sensation & Feeling of tautness, swelling or slight soreness. Size 1mm or less. These gray or white vesicles rupture quickly leaving small red ulcerations. Ballooning degeneration, lipschutz bodies and Tzanck cells are +nt. B.) Varicella Zoster Infection :It is an acute disease caused by varicella zoster virus. TYPES:Chicken box (Varicella) Shingles (herpes Zoster) or Zona (1) Chicken Box:Also called varicella
Age- children. Commonly in winter and spring months. Mode of transmission :- Air borne droplets or direct contact with infected lesions. CLINICAL FEATURES:Incubation period - 2 weeks. SYMPTOMS:Headache,nasopharngitis,& anorexia followed by maculopapular or vesicular eruptions on skin & low grade fever. Secondary infection:Pustules
healing
Small pitting scar

Oral Manifestations:Involve the oral mucosa particularly buccal mucosa, tongue, gingiva, palate. Slightly raised vesicle with erythema. HERPES ZOSTER:- SHINGLES, ZONA FACTORS:Trauma Development of malignancy or tumor. Local X-ray radiation. CLINICAL FEATURES:Sex- Male = Female Prodromal period of 2-4 days. SYMPTOMS:Shooting pain, parasthesia, burning & tenderness. Hutchinsons Sign - Ocular involvement.
Post herpetic neuralgia :- pain may continue for weeks to months. ORAL MANIFESTATION:Result from involvement of 2nd & 3rd div.of trigemnal nerve. It may be found on the Site buccal mucosa, tongue, uvulva pharynx & larynx. Associated with JAMES RAMSAY HUNT SYNDROME. Hoarseness of voice, tinnitus, vertigo and vesicular eruptions. CLINICAL FEATURES:3. Cytomegalic Virus infections:SYMPTOMS:Hepatosplenomegaly,jaundice,petecheal hemorrhage can also occur.
Pneumonia, microcephaly, cerebral calcification and hearing. ORAL MANIFESTATIONS:Patient may suffer from gingivitis & gingival hyperplasia. Oral Ulcers. 4. EPSTEIN-BARR VIRUS INFECTION:Seen in early adulthood Often Characterized by a Syndrome k/a infetive mononucleosis. Also with burkitts lymphoma & hairy leukoplakia.
RNA VIRUS:1.Paramixo virus:(i) Measles:- Also called, rubella/morbilli German Measles. TRANSMISSION:Occurs by direct contact with a person or by droplet infection & respiratory tract.
CLINICAL FEATURES:-
Incubation period - 8 to 10 days. SYMPTOMS:Fever, Malaise, cough, conjunctivitis, photophobia, lacrimation & eruptive lesions of skin & oral mucosa. Sore throat. Appears as tiny red macules or papules which enlarge to form blotchy discolored irregular lesions. O.M. Kopliks spot www.rxdentistry.blogspot.com
PREVENTION:Active immunization: One injection of attenuated measles is given in children over one year. Passive Immunization:- Human Immunoglobin given i.m. under 18 months of age and debilitated children. Dose : 250 Mg. for children under 1 year 500 mg. above this age. (II) MUMPS:Site Major salivary glands but also affects testis, meninges, pancreas, heart and mammary glands. It is also called endemic parotitis.
CLINICAL FEATURES:Incubation period 2 to 3 weeks Age 5-15 Yrs. Sex Male > Female
SYMPTOMS:Headache, chills, moderate fever, vomiting, pain below the ear. 1)HERPANGINA:Also called as Apthous pharyngitis & Vesicular pharyngitis. CLINICAL FEATURES:Age Young Children 3-10 years. Incubation period 2 to 10 days Symptoms Fever, chills, headache, anorexia, Prostration, abdominal pain & vomiting, sore throat, dysphagia & sore mouth.
SITE:Postr. pharynx, tonsil, facial pillars & soft palate. Punctuate Macule Papules & Vesicles
24 to 48 Hrs.
Ulcers ( 1 to 2 mm) (Gray base & inflamed periphery) Healing (1 week) 3. HAND FOOT AND MOUTH DISEASE : CLINICAL FEATURES:Age 6 Months 5 Yrs.
SITE:Hands, feet, legs & arms & buttocks. SYMPTOMS:Anorexia, low-grade fever, lymphadenophathy, diarrhoea, nausea & vomiting. O.M.: The most common sites for oral lesions are hard palate, tongue & buccal mucosa. Vesicular & uncreative lesions. Tongue becomes red and edematous. 3). TOGA VIRUS:Rubella Kopliks spot do not occur. Oral Mucous membr. are not inflamed.
CLINICAL FEATURES:Tonsils may be swollen & congested and red macules may appear on palate. SYMPTOMS:Fever, Malaise & Headache.
HIV INFECTION:1. Lesions strongly associated with HIV Infection. * Candidiasis * Hairy Leukoplakia * Kaposis Sarcoma * Non-Hodgkins Lymphoma * Periodontal disease Lesions less commonly associated with HIV infection. * Bacterial infections * Melanotic hyperpigmentation * Necrotising (ulcerative) stomatitis
2.
3.
* Salivary gland disease * Thrombocytopenic purpura * Ulceration. NOS (not otherwise specified) * Viral infections Lesions rarely Seen in HIV Infection * Bacterial infections * Cat- scratch disease *Drug reactions (ulcerative), erythema multiforme, behenoid, toxic epidermolysis) * Fungal infection other than candidiasis * Histoplasma Capsulatum * Aspergilus flavus * Neurologic disturbances * Recurrent apthous stomatitis * Viral infections
ACUTE HERPETIC GNIGIVOSTOMATITIS
HERPES LABIALIS
VARICELLA
HERPES ZOSTER RECURRENT HERPETIC INFECTION HERPES SIMPLEX
CYTOMEGALOVIRUS INFECTION
HARPANGINA
MUMPS
Hand- Foot - & Mouth Disease
RUBEOLA
HIV ASSOICATED CANDIDIASIS HIV ASSOICATED GINGIVITIS HIV ASSOICATED PERIODONTITIS www.rxdentistry.blogspot.com
HIV ASSOCIATED HAIRY LEUKOPLAKIA HIV ASSOCIATED RECURRENT HERPETIC INFECTION
HIV ASSOCIATED KAPOSI s SARCOMA
HERPETIC WHITLOW

Viral Lesions Oral Patho

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VIRAL LESIONS

are already present.

Small pitting scar

ACUTE HERPETIC GNIGIVOSTOMATITIS

HERPES ZOSTER RECURRENT HERPETIC INFECTION HERPES SIMPLEX

Hand- Foot - & Mouth Disease

HIV ASSOCIATED HAIRY LEUKOPLAKIA HIV ASSOCIATED RECURRENT HERPETIC INFECTION

HIV ASSOCIATED KAPOSI s SARCOMA

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