Documenti di Didattica
Documenti di Professioni
Documenti di Cultura
Dr. Mahmudul Huque Endocrinologist Department of Medicine Holy Family Red Crescent Medical College
Hormones: Signaling bio-molecules - Proteins, steroids or amines, regulates subcelluler events: in conjunction with N/S regulate organs.
Pituitary
7 In number
endo. Gland
Classification of endocrine diseases hormone excess / Deficiency / Hypersensitivity / Resistance / Tumour example: Thyroid Gland
1. HRC
Protein synthesis
2.
2nd messengers: CAMP Releasing hormones PTH. Calcitonin CGMP ANP by DNA or other effect Ca ++1 Phosphatidyt inositol GnRH, TRH catecols. Unknown Insulin, GH, PRL
Axis Based
e.g. TSH, FT4 / PTH, calcium LH, testosterone / ACTH, Cortisol Glucose / Insulin Appropriate in detecting Deficiency, ectopic, resistance,
Dynamic tests
For subtle lesions
Suppression / Stimulation of endogenous Hormone production Stimulation tests to see hypo-function Stimulatory agent Tropic hormone
Measured Response Cortisol / Renin, Aldosterone Testosterone GH, ACTH GH Trophics T4 T3 uptake
Pituitary Thyroid
Pancreas
Glucose
Insulin
Suppression tests
To sec hyper function & negative feedback control.
Administered a hormone or regulatory substance & suppression of endogenous hormone production is assessed.