HYDERABAD CAMPUS FIRST SEMESTER 2010-2011 nCSI1AL hosplLal W PosplLal ls a complex organlzaLlon and an lnsLlLuLe whlch provldes healLh Lo peoples Lhrough compllcaLed buL speclallzed sclenLlflc equlpmenLs and a Leam of Lralned medlcal sLaff educaLed ln Lhe problems of modern medlcal sclence W 1hus Lhe hosplLal ls a speclallzed body where Lhe paLlenL care ls Lhe focus polnL and abouL whlch all acLlvlLles of Lhe hosplLal revolve LASSIIIA1ICN CI nCSI1ALS Can be done on Lhree ways A) LINIAL 8ASIS CI LASSIIIA1ICN W MaLernlLy hosplLals W Surgery (Surglcal hosplLals) Cynaecologlcal CrLhopaedlc CLolaryngologlcal CardloLhoraclc Ceneral surgery neurologlcal kldney W Medlclne Ceneral uenLal edlaLrlcs Cancer Communlcable dlsease MenLal urug addlcLlon rehablllLaLlon 8) CWNLkSnI Ck CN1kCL 8ASIS W CovernmenL ubllc healLh cenLers or clvll hosplLals MlllLary hosplLals W non CovernmenL rlvaLe run CharlLable LrusL ) SS1LM CI MLDIINL 8ASIS AllopaLhlc PomeopaLhlc Ayurvedlc naLuropaLhy unanl nCSI1AL nAkMA AND I1S CkGANISA1ICN nCSI1AL nAkMA ueflnlLlon P ls Lhe deparLmenL servlce or a domaln ln Lhe hosplLal organlzaLlon managed under Lhe dlrecLlon of a professlonally compeLenL legally quallfled pharmaclsL and deals wlLh W Supply of drugs medlclnes and allled producLs Lo Lhe nurslng unlLs W lllllng of prescrlpLlons for ouLpaLlenLs and dlspenslng as per lnLenLlon of a physlclan W ManufacLurlng of Lhe drugs and formulaLlons ln bulk and ln parLlcular Lhe large volume parenLerals whlch are requlred for use of lndoor paLlenLs W SLorage and dlspenslng of narcoLlc and blologlcal producLs W Supply and sLorage of anclllary producLs and arLlcles requlred ln Lhe hosplLal nAkMALU1IAL SLkVILS Comprlses Lhe servlces rendered Lo Lhe paLlenL Lhrough a number of acLlvlLles Ma[or acLlvlLles lnclude ulspenslng of drugs and medlclnes as per Lhe prescrlpLlons of Lhe docLor for Lhe ouLpaLlenLs and Lhe lnpaLlenLs ManagemenL of Lhe sLores whlch lncludes urchase of drugs and medlclnes and oLher allled sLores as per Lhe recommendaLlons of Lhe 1C rovldlng lnsLrucLlons for proper sLorage of such drugs and medlclnes MalnLenance of proper records of Lhe drugs purchased and Lhe dlsLrlbuLlon Lhereof ManufacLure and dlsLrlbuLlon of medlcamenLs and producLs such as 1ransfuslon flulds and oLher parenLeral producLs whlch are noL manufacLured and markeLed 1ableLs Capsules LxLernal use preparaLlons llke olnLmenLs SLock mlxLures as per hosplLal formulary rovldlng LherapeuLlc drug monlLorlng (1uM) LsLabllshmenL and malnLenance of urug lnformaLlon CenLers (ulC) aLlenL counsellng servlce MalnLalnlng llalson wlLh medlcal sLaff nurslng sLaff and Lhe paLlenLs 1o malnLaln Lhe nurslng deparLmenL and Lhe cenLral sLerlle supply unlL ln Lhe hosplLal arLlclpaLe ln Lhe Leachlng programs of Lhe nurslng and pharmacy sLudenLs IUN1ICNS CI A nCSI1AL nAkMAIS1 W 1o provlde and evaluaLe pharmaceuLlcal servlces and Lhereby supporLlng Lhe medlcal sLaff wlLh due conslderaLlon of Lhe ob[ecLlves and pollcles of Lhe hosplLal W 1o draw a plan for hosplLal pharmacy admlnlsLraLlon W 1o esLabllsh a llalson beLween admlnlsLraLlve auLhorlLles and medlcal docLors who wlll order drugs and anclllary producLs ln Lhe hosplLal W 1o esLlmaLe Lhe requlremenLs of Lhe deparLmenLs and enforce Lhe pollcles and procedures for Lhe recrulLmenL of adequaLe and compeLenL sLaff W 1o provlde Lhe means and meLhods by whlch Lhe personnel can work wlLh oLher groups ln lnLerpreLlng ob[ecLlves and pollcles of Lhe hosplLal W 1o develop and malnLaln an effecLlve sysLem of cllnlcal and admlnlsLraLlve records and reporLs W 1o parLlclpaLe ln and adhere Lo Lhe flnanclal plan of Lhe operaLlon of a hosplLal W 1o esLlmaLe Lhe needs of faclllLles supplles and equlpmenLs and Lo see LhaL Lhere ls a proper conLrol of lnvenLory sLocks dlspenslng and manufacLurlng of Lhe medlcamenLs W 1o lnlLlaLe uLlllze and parLlclpaLe ln research pro[ecLs deslgned for Lhe lmprovemenL of paLlenL care and oLher admlnlsLraLlve and hosplLal servlces W 1o provlde and puL lnLo pracLlce a program for conLlnulLy educaLlon Lo all personals W 1o parLlclpaLe and adhere Lo Lhe safeLy programs of Lhe hosplLal W 1o provlde and Lo puL lnLo pracLlce a program of conLlnulng educaLlon of all personals W 1o parLlclpaLe and/or faclllLaLe all educaLlonal programme whlch lnclude sLudenL experlences ln Lhe deparLmenL Set up of hosp|ta| pharmacy DLAk1MLN1 CI nAkMA DLAk1MLN1 CI nAkMA nosp|ta|'s comm|ttees nosp|ta| adm|n|strat|on at|ents nosp|ta|'s c||n|ca| staff nosp|ta|'s other departments nosp|ta|'s nurs|ng staff Iunct|ons and respons|b|||t|es of the nCD of pharmacy and h|s staff W PCu have Lo ensure LhaL pharmaclsLs funcLlonlng ln dlfferenL areas carry ouL Lhelr asslgned funcLlons and duLles efflclenLly and ls aware of hls responslblllLles Lowards lLs sLaff and Lo Lhe hosplLal admlnlsLraLlon Suggested pattern of a setup of hosp|ta| pharmacy 1PL ul8LC1C8 C8 uLAn C8 MLulCAL SuL8ln1LnuLn1 1PL ul8LC1C8 C8 uLAn C8 MLulCAL SuL8ln1LnuLn1 ul8LC1C8 Cl PA8MACLu1lCAL SL8vlCLS (MPA8M 8LlL8A8L? Wl1P PA8MACCLCC?) ul8LC1C8 Cl PA8MACLu1lCAL SL8vlCLS (MPA8M 8LlL8A8L? Wl1P PA8MACCLCC?) PA8MAC? lnCPA8CL PA8MAC? lnCPA8CL MAnulAC1u8lnC Mharm wlLh speclallzaLlon ln pharmaceuLlcal Lechnology MAnulAC1u8lnC Mharm wlLh speclallzaLlon ln pharmaceuLlcal Lechnology ulSLnSlnC Anu ulS18l8u1lCn Cl u8uCS CuLdoor lndoor 8pharm asslsLed by upharm as [unlor pharmaclsL ulSLnSlnC Anu ulS18l8u1lCn Cl u8uCS CuLdoor lndoor 8pharm asslsLed by upharm as [unlor pharmaclsL CC Mharm wlLh speclallzaLlon ln AnalyLlcal chemlsLry asslsLed by 8pharm Lralned ln mlcroblology and pyrogen LesLlng CC Mharm wlLh speclallzaLlon ln AnalyLlcal chemlsLry asslsLed by 8pharm Lralned ln mlcroblology and pyrogen LesLlng u8uC MCnl1C8lnC SL8vlCLS Anu u8uCS lnlC8MA1lCn SL8vlCLS Mharm wlLh speclallzaLlon ln harmacology u8uC MCnl1C8lnC SL8vlCLS Anu u8uCS lnlC8MA1lCn SL8vlCLS Mharm wlLh speclallzaLlon ln harmacology MLulCAL 8LCC8uS Anu MlSCLLLAnLCuS uu1lLS (8harm or upharm) MLulCAL 8LCC8uS Anu MlSCLLLAnLCuS uu1lLS (8harm or upharm) Inpat|ent or |ndoor pharmac|sts respons|b|||t|es A) LN1kAL DISLNSING AkLA 1o ensure LhaL all drugs are sLored dlspensed correcLly 1o check Lhe accuracy of Lhe dosages prepared especlally of lnLravenous admlxLure and unlL doses 1o keep proper records and preparaLlon of bllls 1o coordlnaLe Lhe overall pharmaceuLlcal needs of Lhe paLlenL care" areas wlLhln Lhe cenLral dlspenslng area 1o ensure LhaL Lhe esLabllshed pollcles and procedures lald down are followed 1o malnLaln professlonal compeLence parLlcularly LhaL keeps hlm updaLed wlLh of lnformaLlon 1o communlcaLe wlLh all pharmacy sLaff regardlng new developmenLs ln Lhe area and asslsLs ln evaluaLlons of employees of hls secLlon 1o ensure LhaL Lhe new personnel ln hls secLlon are properly Lralned ln Lhe pollcles and procedures of Lhe cenLral dlspenslng area 1o coordlnaLes Lhe acLlvlLles of Lhe area wlLh Lhe avallable sLaff Lo make use of Lhe besL posslble use of Lhe personnel and resources 8) A1ILN1 AkL AkLAS (wards operaLlon LheaLres and oLher deparLmenLs where drugs of speclal caLegorles are used) 1he pharmaclsL ln charge of Lhls secLlon has goL followlng responslblllLles 1o malnLaln a llalson wlLh nurses 8evlewlng of drug admlnlsLraLlon ln each paLlenL perlodlcally 1o provlde lnsLrucLlon and asslsLance Lo Lhe [unlor pharmaclsLs as needed ln deallng wlLh dlfflculL paLlenLs and new procedures 1o coordlnaLes over all pharmaceuLlcals servlces on Lhe runnlng unlL level ) DIkL1 A1ILN1 AkL AkLAS Pls responslblllLles lnvolve ldenLlflcaLlon of drugs broughL lnLo Lhe hosplLal by Lhe paLlenL CbLalnlng paLlenLs medlcaLlon hlsLory and communlcaLlng all Lhe lnformaLlon Lo Lhe physlclans 1o asslsL ln Lhe selecLlon of drugs producLs and Lhelr ldenLlLles Also Lo asslsL physlclan ln selecLlng dosage paLLern and schedules and asslgns Lhe Llmlngs for Lhe drug admlnlsLraLlon 1o monlLor paLlenLs LoLal drugs Lherapy for LffecLlveness(lneffecLlveness) slde effecLs LoxlclLles allerglc drug reacLlons drug lnLeracLlons and as Lhelr dlsLrlbuLlon and concenLraLlon ln organs and Llssues by pharmacoklneLlc and pharmacodynamlc meLhods Counsellng paLlenLs on MedlcaLlons LhaL are Loo be self admlnlsLered ln Lhe hosplLal 8egardlng Lhe use of dlscharge medlclnes arLlclpaLlng ln cardlo pulmonary emergencles by rocuremenL or preparaLlon of drugs needed CharLlng all medlcaLlons glven erformlng cardlo pulmonary resusclLaLlon lf necessary D) GLNLkAL kLSCNSI8ILI1ILS W 1o provlde ln servlce Lralnlng and educaLlon for Lhe pharmaclsL pharmacy sLudenLs nurses and nurslng sLudenLs physlclans and medlcal sLudenLs W Pe has Lo provlde lnformaLlon regardlng drugs Lo Lhe physlclans nurses and oLher healLh care personnel CuLdoor pharmaclsLs responslblllLles W ulvlded lnLo Lhree caLegorles W 1hose regardlng CenLral dlspenslng area aLlenL care areas Ceneral responslblllLles A) LN1kAL DISLNSING AkLA harmaclsL should ensure W roper Lechnlques are used for exLemporaneous compoundlng W AdequaLe record keeplng and bllllng ln respecL of paLlenL's medlcaLlon parLlculars records of lnvesLlgaLlonal drugs records of ouLpaLlenL bllls malnLalnlng and preparlng of all records W CorrecLly malnLalnlng of prescrlpLlon flles W keep Lhe ouLdoor pharmacy ln a neaL and Lldy manner 8) A1ILN1 AkL AkLAS W 1o perlodlcally lnspecL Lhe medlcaLlon areas on Lhe nurslng unlL and Lo make sure LhaL Lhey are always kepL adequaLely supplled wlLh drugs and oLher arLlcles requlred W 1o ldenLlfy Lhe drugs broughL lnLo cllnlc by Lhe paLlenL and record Lhe paLlenLs medlcaLlon hlsLory and communlcaLlng Lhe same Lo Lhe physlclans concerned Pe also asslsL Lhem ln selecLlon of drugs reglmen and schedules and selecLlon of correcL drug producLs and Lhelr enLlLles W MonlLorlng of drugs W 1o counsel Lhe paLlenLs on proper use of Lhelr medlcaLlon and prepare Lhe medlcaLlons for lnLravenous admlnlsLraLlon ) GLNLkAL kLSCNSI8ILI1ILS 1o coordlnaLe Lhe overall pharmaceuLlcal needs of Lhe ouLdoor servlce area and exerclse adequaLe conLrol over such drugs 1o ensure LhaL all drugs are handled properly such as sLorage of lnvesLlgaLlonal drugs 1o parLlclpaLe ln cardlopulmonary emergencles 1o provlde for ln servlce educaLlon and Lralnlng for pharmaclsLs pharmacy lLems le pharmacy sLudenLs send for pracLlcal Lralnlng as a parL of dlploma or degree courses nurses harmacy and therapeut|c comm|ttee (1) 1 W ls a pollcy framlng and recommendlng body Lo Lhe medlcal sLaff and Lhe admlnlsLraLlon of hosplLal on maLLers relaLed Lo Lhe LherapeuLlc use of drugs W 1C ls composed of physlclans pharmaclsLs and oLher healLh professlonals selecLed wlLh Lhe lncluslon of medlcal sLaff C8IL1IVLS CI 1 W AuvlSC8? W LuuCA1lCnAL W u8uC SAlL1? Anu AuvL8SL u8uC MCnl1C8lnC ompos|t|on of 1 Cenerally 1C ls composed of 1) AL leasL Lhree physlclans from Lhe medlcal sLaff 2) A pharmaclsL 3) A represenLaLlve of Lhe nurslng sLaff and 4) An hosplLal admlnlsLraLor wlLh hls/her deslgnaLed an exofflclo member of Lhe commlLLee one of Lhe physlclans may be appolnLed as Lhe chalrman of 1C harmaclsL funcLlons usually as Lhe secreLary and Lherefore deslgnaLed as Lhe secreLary of Lhe commlLLee CommlLLee should meeL regularly aL leasL slx Llmes ln a year and also when requlred 8ole of pharmaclsLs ln 1C W reparaLlon of Lhe agenda and supplemenLary maLerlals requlred for commlLLee meeLlng and furnlsh lL Lo Lhe commlLLee members ln advance so LhaL members can sLudy properly before Lhe meeLlng W 8evlew of conLenLs of Lhe PosplLal lormulary for Lhe purpose of brlnglng lL up Lo daLe and deleLlng of producLs noL consldered necessary for use W 8evlew and/or adopLlon of lnvesLlgaLlonal drugs currenLly under processlng ln Lhe hosplLal W 8evlew of slde effecLs adverse drug reacLlons Loxlc effecLs drug lnLeracLlons of drugs reporLed by varlous unlLs of Lhe hosplLal and broughL lnLo Lhe noLlce of Lhe commlLLee by Lhe ulC W 8evlew of drug safeLy ln hosplLal W urug safeLy ls Lhe moral legal and professlonal obllgaLlon of Lhe pharmaclsLs ln wesLern counLrles W PosplLal musL employ a quallfled aL leasL a reglsLered pharmaclsL wlLh 8harm degree as Lhe chlef pharmaclsL and Lhe resL may be aL leasL dlploma holders ln pharmacy W PosplLal should noL permlL a non pharmaclsL personnel Lo dlspense drug and allled maLerlals W Lngage ln Leachlng programme Lo famlllarlze Lhe nurslng and resldenL sLaff wlLh new drugs and Lo Leach Lhe sLudenL nurses Lhe baslc course of pharmaceuLlcal maLhemaLlcs and pharmacology 8LA8A1lCn Anu MAln1LnAnCL Cl LML8CLnC? kl1S 1o declde abouL Lhe drugs and oLher supplles LhaL should be presenL ln Lhe Lmergency klLs (boxes conLalnlng emergency drugs) 1o place Lmergency klLs so LhaL lL ls readlly avallable for use aL Lhe bed slde speclfled place ln cllnlc emergency ward and ln Lhe speclal procedure room of Lhe deparLmenL of radlology and lLs rouLlne sLocklng W P ls a conLlnuously revlsed compllaLlon of pharmaceuLlcal dosage agenLs and Lhelr forms eLc whlch reflecLs Lhe currenL cllnlcal [udgmenL of Lhe medlcal sLaff W PosplLal formulary sysLem ls a meLhod whereby Lhe medlcal sLaff of a hosplLal wlLh Lhe help of 1C selecLs and evaluaLes medlclnal agenLs and Lhelr dosage forms whlch are consldered Lo be mosL useful ln Lhe paLlenL care W Pl sysLem provldes lnformaLlon for procurlng prescrlblng dlspenslng and admlnlsLraLlon of drugs under nonproprleLary or proprleLary names naLlonal lormulary of lndla by MlnlsLry of PealLh and lamlly Welfare CovernmenL of lndla kCLL CI nAkMAIS1 IN kLAkA1ICN CI nCSI1AL ICkMULAk PCSl1AL lC8MuLA8? W harmaclsL ln Lhe 1C have a key role ln developlng pollcles and procedures governlng Lhe Pl W 1he chlef pharmaclsL have Lhe prlmary responslblllLy for Lhe preparaLlon of Pl W harmaclsL wlLh Lhe advlce and guldance of 1C shall ascerLaln Lhe quanLlLy and source of supply of all drugs chemlcals blologlcals and pharmaceuLlcal preparaLlons used for Lhe dlagnosls and LreaLmenL of paLlenLs W harmaclsL should ensure LhaL quallLy of drugs ls noL compromlsed by economlc conslderaLlons kCLL CI nAkMAIS1 LINIAL nAkMA W Cllnlcal pharmacy ls a branch of harmacy where pharmaclsLs provlde paLlenL care LhaL opLlmlzes Lhe use of medlcaLlon and promoLes healLh wellness and dlsease prevenLlon W 1he Cllnlcal PosplLal harmaclsL ls responslble for all cllnlcal pharmacy acLlvlLles wlLhln Lhe pharmacy and wards PosplLal W Cllnlcal pharmaclsL ls an lmporLanL parL of Lhe healLhcare Leam W Cllnlcal pharmaclsLs are a prlmary source of sclenLlflcally valld lnformaLlon and advlce regardlng Lhe safe approprlaLe and cosLeffecLlve use of medlcaLlons W 1he pharmaclsL works ln coordlnaLlon wlLh Lhe docLors for Lhe beLLer paLlenL healLhcare 1hey have very speclflc roles whlch alm aL assurlng paLlenL safeLy Scope of c||n|ca| pharmacy W urug ulsLrlbuLlon SysLems W urug lnformaLlon W urug uLlllzaLlon W urug LvaluaLlon and SelecLlon W MedlcaLlon 1herapy ManagemenL W lormal LducaLlon and 1ralnlng rogram W Mlscellaneous AppllcaLlon of LlecLronlc uaLa rocesslng(Lu) A1IVI1ILS CI LINIAL nAkMAIS1S 1he prlnclple acLlvlLles of a cllnlcal pharmaclsL lnclude W onsu|t|ng Analyslng Lheraples advlslng healLh care pracLlLloners on Lhe correcLness of drug Lherapy and provldlng pharmaceuLlcal care Lo paLlenLs boLh aL hosplLal and aL communlLy level W Se|ect|on of drugs ueflnlng drug formularles or llmlLed llsLs of drugs ln collaboraLlon wlLh hosplLal docLors general pracLlLloners and declslon makers W Drug |nformat|on Seeklng lnformaLlon and crlLlcally evaluaLlng sclenLlflc llLeraLure organlslng lnformaLlon servlces for boLh Lhe healLh care pracLlLloners and Lhe paLlenLs W Drug use stud|es and research urug use sLudles/ pharmacoepldemlology/ ouLcome research/ pharmacovlgllance and vlgllance ln medlclnal devlces collecLlng daLa on drug Lheraples Lhelr cosLs and paLlenL ouLcome Lhrough sLrucLured and sclenLlflc meLhods W harmacok|net|cs] therapeut|c drug mon|tor|ng SLudylng Lhe klneLlcs of drugs and opLlmlslng Lhe dosage W Iormu|at|on and preparat|on lormulaLlon and preparaLlon of medlclnal producLs and devlces accordlng Lo accepLable sLandards Lo meeL speclflc paLlenLs needs W ||n|ca| 1r|a|s lannlng evaluaLlng and parLlclpaLlng ln cllnlcal Lrlals W harmacoeconomy uslng Lhe resulLs of cllnlcal Lrlals and ouLcome sLudles Lo deLermlne cosL effecLlveness evaluaLlons W D|spensat|on Adm|n|strat|on sLudylng and developlng sysLems for Lhe dlspenslng and admlnlsLraLlon of medlclnal producLs and devlces LhaL can guaranLee a hlgher securlLy ln admlnlsLraLlon a reducLlon of expendlLure and a reducLlon ln medlcaLlon errors W 1each|ng 1ra|n|ng re and posLgraduaLe Leachlng and acLlvlLles Lo provlde Lralnlng and educaLlon programmes for pharmaclsLs and oLher healLh care pracLlLloners W reparaLlon of paLlenL medlcaLlon hlsLory charL W lL lnvolves ln lncreaslng Lhe knowledge abouL Lhe dlsease and Lhelr drug Lherapy Pe can gulde Lhe paLlenL for proper use of drug Lherapy and posslble drug lnLeracLlon Pe can also advlce for Lhe drug compllance W arLlclpaLlon ln medlcal emergencles W lL also provldes Lhe provlslon of consulLaLlon ln varlous areas llke LoLal parenLeral nuLrlLlon lnLravenous Lherapy cllnlcal pharmacoklneLlcs selecLlon of drug Lherapy and deLermlnaLlon of LherapeuLlc end polnL W ManagemenL of chronlc dlseases keferences 1. Merchant, S. H., Qadry, J. S., A Textbook oI Hospital Pharmacy, B. S. Shah Prakashan, 2nd Ed., 1994. 2. Internet Sources