COATING OF

NANOPARTICLES
CLASS PRESENTATION
 INTRODUCTION:
 When talking about surface coatings
of nanomaterials often terms such as
modification, functionalization or
stabilization are used. This diversity
in terms reflects the different
motivations for using a coating or for
its intended function.
Role of the Coating Remarks Schematic
coating material images

Increased Molecules, Single

particle polymers layers,
stability in (10 – 100 mostly used
solutions kDa), in
charged production
polymers and
(electrolytes, processing
surfactants)
Role of the Coating Remarks Schematic
coating material images

Improveme Molecules, To facilitate

                                         
                                         
                                         
nt of polymers, the  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
wettability inorganic preparation  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
layers of mixtures  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
of  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

nanoparticl  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
           

es with
water, or
organic
solvents
and
polymers
(hydrophobi
c surfaces)
Role of the Coating Remarks Schematic
coating material images

Improveme Inorganic Fluorescenc

nt of layers, e of
physical mostly quantum
and silicon dots (QDs)
chemical dioxide or can be
functions, ZnO in significantly
increased combinatio increased
efficiency n with SiO2 when
saturating
free surface
bonds
Role of the Coating Remarks Schematic
coating material images

Cost and Noble Application

material metals, e.g. of thin,
savings palladium incomplete
layers of a
noble metal
catalyst on
a cost-
efficient
substrate
material
(core)
Role of the Coating Remarks Schematic
coating material images

Protective Organic Protection

function layers of particle
functionalit
y, e.g. from
catalyst
poisons
Role of the Coating Remarks Schematic
coating material images

Biocompati Biocompati Biocompati

bility and ble ble SiO2 or
functionalit polymers Polyethylen
y and e glycol
inorganic (PEG) can
layers, decrease
antibodies protein
and adsorption,
peptides diagnostics
and drug-
transport
 COATING IN MANUFACTURING
AND PROCESSING:
 During the production, processing or for the final
product most Nano-objects are used in the form of a
suspension having been dispersed in an (aqueous)
medium. To stabilize such suspensions, molecules
or polymers are linked to the particle surface.
 In case of gold (Au) nanoparticles citric acid is often
used, while polymers are well-suited for titanium
dioxide (TiO2) particles. Another important property
of nanoobjects is the wettability with water or
organic solvents. This feature (wettability) can be
adjusted and fine-tuned with specific coatings.
 COATINGS TO IMPROVE THE
NANO-EFFECT:
 The second important group of coatings has been
designed to improve or strengthen the Nano-effects. In
particular, quantum dots (QDs), whose core is
composed of cadmium selenide molecules (CdSe),
require a coating.
 First of all CdSe - QDs are instable and dissolve
subsequently. Secondly due to the surface defects of
QDs the overall fluorescence is reduced. Therefore an
intended coating for quantum dots has to meet certain
chemical and physical requirements.
 It should be transparent to not affect the particle
fluorescence and should also be able to provide for the
desired long-term stability.
 COATING OF NANO OBJECTS
FOR MEDICAL APPLICATION:
The desired or chosen coating has to
fulfil the following criteria:
 first to ensure biocompatibility
 secondly a controlled residence time in
the blood and
 thirdly the targeted transport to certain
cells or organs.
THANK YOU!