Glomerulonephritis What is Chronic Glomerulonephritis?
• A condition characterized by irreversible and
progressive glomerular and tubulointerstitial fibrosis. • May lead to a reduction in the glomerular filtration (GFR) and retention of uremic toxins. • The third leading cause of CKD, and accounting for about 10% of all patients on dialysis. Risk Factors • Diabetes • Cardiovascular disease • Family history of kidney disease • Obesity • Older age • Smokin Signs and Symptoms • Blood or protein in the urine • High blood pressure • Swollen ankles or face because of water retention • Urinating frequently during the night • Bubbles or foam in the urine, caused by excess protein. Diagnostic Tests • Urine test Shows red blood cells and red cell casts in your urine An indicator of possible damage to the glomeruli Shows WBC, a common indicator of infection or inflammation, and increased protein which can indicate nephron damage Diagnostic Tests • Blood Test Provide information about kidney damage and impairment of the glomeruli by measuring levels of waste products, such as creatinine and blood urea nitrogen. Diagnostic Tests • Kidney biopsy Involves using a special needle to extract small pieces of kidney tissue for microscopic examination to help determine the cause of the inflammation. Always necessary to confirm a diagnosis of glomerulonephritis. Diagnostic Tests • CT Scan Detect and monitor diseases and conditions such as cancer, heart disease, lung nodules and liver masses. Useful to better define renal masses and cysts usually noted on ultrasonograms also the most sensitive test for identifying renal stones. Anatomy • The kidney lie on either side of the spine in the retroperitoneal space between the parietal peritoneum and the posterior abdominal wall. • The left kidney is located at about the T12 to L3 vertebrae, whereas the right is lower due to slight displacement by the liver. • They are about 11- 14 cm in length, 6 cm wide, and 4 cm thick. • Each kidney weighs about 125-175 g in males and 115-155 g in females. Physiology Physiology Nursing Management/ Intervention • Monitor vital signs - always maintain a reasonable blood pressure • Monitor laboratory results - to know what actions they must do to improve the patient’s health status • Evaluate patient’s status - the patient might be getting anxious because of the procedure. - Make sure to explain every procedure to avoid confusion on the patient. • Health teachings - Teach the patient on how to maintain a good health status. Promote healthy lifestyle and healthy diet for the patient. Medical Management • Peritoneal dialysis (PD) – A treatment that uses the lining of the abdomen and cleaning solution called dialysate to clean the blood. • Hemodialysis – A dialysis machine and a special filter called an artificial kidney, or a dialyzer, are used to clean the blood. Surgical Management • Kidney transplantation – Organ transplant of a kidney into a patient with stage end-stage kidney disease Drug Analysis Drug Pharmacologic Class Therapeutic Class
• Hydralazine Hydralazine is in Hydralazine is in a
(Apresoline) a class of class od medications medications called called vasodilators. It antihypertensives. works by relaxing Something that the blood vessels so reduces high blood that blood can flow pressure. more easily through the body. Discharge Planning • Medication Instructed to complied strictly with the following home medications avoid aspirin products. To prevent bleeding. • Exercise Bed rest • Treatment Encourage use of soft toothbrush, avoiding straining forstool, and forceful nose blowing Patients who are sent home should be monitored daily by health care providers or temperature pattern, volume of fluid intake and losses, urine output (volume and frequency), warning signs, signs of plasma leakage and bleeding, hematocrit, and white blood cell and platelet counts. Discharge Planning • Health teaching D- discuss the possible source of infection of the disease. E- educate the family/patient on how to eliminate those vectors N- Never stocked water in a container without cover. G- Gallon, container and tires must have proper way of disposal. U- Use insecticides at home to kill or reduce mosquito. E- Encourage the family of the patient to clean the surroundings to destroy the breeding places of mosquito. Discharge Planning • Outpatient Remind patients that regular check-ups are important to ensure that the patient condition is constantly monitored by the doctor. • Diet high carbohydrate diet provides caloric requirements of the body Encourage nutritious foods like vegetables, meat and fruits. Encourage oral intake of oral rehydration solution (ORS), fruit juice and other fluids containing electrolytes and sugar to replace losses from ever and vomiting.