DOSAGE CALCULATIONS - II

Dr. V.GOWRI
 DOSAGE CALCULATIONS
QUESTION - 6

• How many days will a 60 ml of bottle of

Cefaclor oral suspension (125 mg/ 5 ml) last
if the patient is to take 125 mg tds?
 DOSAGE CALCULATIONS
ANSWER - 6
• Amount required per day = 125mg tds = 5 ml tds ( 15
ml)

• 60 ml will last for = 60 / 15 = 4 days

Answer: 4 days
 DOSAGE CALCULATIONS
QUESTION - 7

• For a 26 year old lady of weight 50 kg and Hb 8gm

calculate the iron requirement. How many
injections are needed to replenish the iron store?

• NOTE: 100mg of iron dextran contained in 2ml of

injection
 DOSAGE CALCULATIONS
ANSWER - 7
• Iron requirement: 4.4 x body weight ( Kg) x Hb deficit (gm
/ dl )
• 4 .4 x 50 x (14-8) = 1320 mg of elemental iron
• 2ml contains = 100 mg of iron
• ? ml contains 1320 mg of iron
• 26ml contains 1320 mg of iron
• 1 injection contains 2 ml
• ? injections – 26ml

• 13 injections
 DOSAGE CALCULATIONS
QUESTION - 8

How many mg of lignocaine is present

in 30 ml vial of 2% lignocaine?
 DOSAGE CALCULATIONS
ANSWER - 8
• 2% solution = 2 gm in 100 ml (2000 mg)

• 100 ml contains = 2000 mg

• 30 ml contains = 2000 / 100 x 30 = 600 mg

• Answer: 30 ml vial of 2% lignocaine contains 600 mg

 DOSAGE CALCULATIONS
QUESTION - 9

• What is the quantity of Adrenaline present in 10

ml vial of 1: 100,000?
• And what is the amount in each ml?
 DOSAGE CALCULATIONS
ANSWER - 9
• 1: 100,000 Solution means 1 gm (1000 mg ) present in 100,000 ml
• 100,000 ml contains = 1000 mg
• 10 ml contains = 1000 / 100,000 x 10 = 0. 1 mg
• 1 ml contains =0.01 mg

Answer: Amount of adrenaline present in the vial is 0. 1 mg

• One ml contains 0. 01 mg
 DOSAGE CALCULATIONS
QUESTION - 10
• An adult male of weight 60 kg with cardiogenic shock
was given dopamine iv infusion of 10µgm / kg/ min.
• Calculate the number of drops per minute to be
infused.
• NOTE: Inj.Dopamine 10 ml (40mg/ml) 1ml = 20
drops
 DOSAGE CALCULATIONS
ANSWER - 10
• 495 ml of 5% dextrose mixed with 5ml of inj. Dopamine
• 5 ml of inj. Dopamine contains = 40 x 5 = 200 mg dopamine
• 500 ml iv fluid contains = 200mg or 200,000 microgram of dopamine
• Infusion rate for this 60 kg weight man is = (10mcg X 60 / min) = 600 microgram
per minute
• Amount of fluid needed to infuse 600 µgm of dopamine = 500/ 200,000 x 600 =
1.5 ml
• 1 ml = 20 drops
• 1.5 ml = 20/ 1.5 = 30 drops
• Answer: 30 drops/ minute