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LIPIDS
Lecture 2
Classification of lipids
Simple lipids
Complex lipids
Derived lipids
Classification of lipids
Simple lipid Complex lipid Derived lipid
• They are neutral “uncharged” due to the absence of ionisable groups in it.
• They are the most abundant lipids in nature.
• They constitute about 98% of the lipids of adipose tissue, 30% of plasma or liver,
and less than 10 % of erythrocyte lipids.
• They are esters of glycerol with various fatty acids.
• The difference between fat and oil is only physical. Thus, oil is a liquid while fat is a
solid at room temperature.
>> This is mainly due to presence/absence of unsaturated fatty acids :
>> In general, oils “from plant origin” are high in unsaturated and low in saturated fatty acids. Fats
“from animal sources” are high in saturated and low in unsaturated fatty acids.
Simple 1- Neutral
Lipids fats or oils
1. Phospholipids
2. Glycolipids
3. Lipoproteins
Complex 1. Phospholipids
lipids
• Classification of Lipoproteins:
Plasma lipoprotein can be divided into 5 classes by ultra centrifugation
technique (based on density)
chylomicrons
Very Low-Density Lipoproteins (VLDL)
Intermediate Density Lipoproteins (IDL)
Low-Density Lipoproteins (LDL)
High-Density Lipoproteins (HDL)
Classification of lipids
Simple lipid Complex lipid Derived lipid
• The main feature of steroids is the ring system of three cyclohexanes and
one cyclopentane in a fused ring system.
• The main feature, as in all lipids, is the large number of carbon hydrogens
which make steroids non-polar.
Steroids
• Steroids include such well known compounds as: Cholesterol
• Cholesterol
• Male & female sex hormones
• Bile acids
• Vitamin D
• Adrenal corticosteroids
Cholesterol
• Cholesterol is an unsaturated steroid alcohol.
• It consists of four fused hydrocarbon rings (A, B, C, and D) called the “steroid
nucleus”), and it has an eight-carbon, branched hydrocarbon chain attached
to carbon 17 of the D ring. Ring A has a hydroxyl group at carbon 3, and ring
B has a double bond between carbon 5 and carbon 6.