Clerkship of pathology

Sub-themes in Parasitology
Malaria
1. Appearance of brain in cerebral malaria
2. Cerebral malaria.
3. Petechialhaemorrhages scattered throughout
the whitematter
4. Ring haemorrhage in cerebral malaria
5. Spleen - showing slaty greyish-red appearance
6. Liver - centrilobular necrosis
7. Kidney - Medullary congestion in severe
malaria, resulting in acute tubular necrosis
 Amoebae infection Pathology
Entamoeba histolytica
Extra-Intestinal Lesions and Abscess
Occurs

A. Hepatic Amebiasis

B. Pulmonary Amebiasis

C. Cerebral Amebiasis
Amoebae infection Pathology
Entamoeba histolytica
 Amoeba infection Pathology
Entamoeba histolytica
• Trophozoites colonize the large
intestine and invade the mucosa.

• They live within the crypts and

mucosa of the large intestinal lining.

• Trophozoites may live

and multiply indefinitely
within the crypts of the LI
mucosa feeding on
starches and mucous
secretions.
 Entamoeba histolytica
Pathology
2. Extra-Intestinal
Lesions and Abscess
Occurs

A. Hepatic Amebiasis

B. Pulmonary Amebiasis

C. Cerebral Amebiasis
Shows movement of
trophozoites from large
intestine to liver via hepatic
portal vein.

Liver Abscesses
 Entamoeba histolytica
Pathology
1. A Primary Ulcer Can Occur.

Flask Shaped
Ulcers
Entamoeba histolytica Pathology

1. A Primary Ulcer Can Occur.

Flask shaped
ulcer
 Roundworm
Short film of Ascaris lumbricoides
infection
Minyoo (Roundworm)
Minyoo (Roundworm)
Minyoo (Roundworm)
migration in the liver
FILARIASIS- Wuchereria
bancrofti
 FILARIASIS- Wuchereria bancrofti

Vector-Culex quinquefaciatus
Microfilaria stage
Pathology in Filariasis
 Pathology in Filariasis
• Hydrocele and Elephantiasis