• is defined as bleeding between monthly periods, prolonged bleeding, or an extremely heavy flow. • Normal menstrual flow lasts approximately 5 days and occurs every 21 to 35 days. Abnormal uterine bleeding is when you bleed between your monthly periods, or when you bleed for too long or it is an extremely heavy flow. WHAT CAUSES ABNORMAL UTERINE BLEEDING? • There are many causes of abnormal uterine bleeding. One major cause is due to structural abnormalities in the uterus. This can take the form of fibroids, which are benign overgrowth of the muscle of the uterus. • Bleeding disorders or platelet dysfunction can cause abnormal bleeding. Early pregnancies can have some bleeding associated with them. Hormonal changes can also be a cause. • Polycystic ovary syndrome (PCOS, cysts in the ovaries) may cause your periods to come at different times or not at all. It is caused when certain hormones are out of balance. When this happens, you may have difficulty getting pregnant. You may grow hair on your body and face. Also, the hair on your scalp may get thinner. • Women who are going into menopause or are in menopause are more apt to have changes in hormones. The changes can cause the lining of the uterus (endometrium) to get thick. This can cause bleeding. • Abnormal uterine bleeding due to ovulatory dysfunction (AUB-O) is abnormal uterine bleeding that, after examination and ultrasonography, cannot be attributed to the usual causes (structural gynecologic abnormalities, cancer, inflammation, systemic disorders, pregnancy, complications of pregnancy, use of oral contraceptives or certain drugs). Treatment is usually with hormone therapy, such as oral contraceptives, or with NSAIDs. PATHOPHYSIOLOGY • During an anovulatory cycle, the corpus luteum does not form. Thus, the normal cyclical secretion of progesterone does not occur, and estrogen stimulates the endometrium unopposed. Without progesterone, the endometrium continues to proliferate, eventually outgrowing its blood supply; it then sloughs incompletely and bleeds irregularly and sometimes profusely or for a long time. When this abnormal process occurs repeatedly, the endometrium can become hyperplastic, sometimes with atypical or cancerous cells. • In ovulatory abnormal uterine bleeding, progesterone secretion is prolonged; irregular shedding of the endometrium results, probably because estrogen levels remain low, near the threshold for bleeding (as occurs during menses). In obese women, ovulatory AUB can occur if estrogen levels are high, resulting in amenorrhea alternating with irregular or prolonged bleeding. PATHOPHYSIOLOGY MANAGEMENT COMPLICATIONS • Chronic bleeding may cause iron deficiency anemia. • If AUB is due to chronic anovulation, infertility may also be present. PATIENT’S PROFILE • NAME: PATIENT X • AGE: 43 • SEX: Female • ADDRESS: Santiago Aliaga, Nueva Ecija • BIRTHDAY: October 15, 1976 • NATIONALITY: Filipino • RELIGION: Catholic • CIVIL STATUS: Married • ADMITING DIAGNOSIS: Abnormal Uterine Bleeding • FINAL DIAGNOSIS: Endometrial Polyps • Uterine polyps are growths attached to the inner wall of the uterus that extend into the uterine cavity. • Overgrowth of cells in the lining of the uterus leads to the formation of uterine polyps, also known as endometrial polyps. • These polyps are usually noncancerous, although some can be cancerous or can eventually turn into cancer (precancerous polyps) NURSING CARE PLAN MEDICATION • Tranexamic Acid IV every 8 hours • Ascorbic Acid 500 mg BID, PO • Ferrous sulfate + Vitamin B-Complex BID, PO TRANEXAMIC ACID • A medication used to treat or prevent excessive blood loss from major trauma, postpartum bleeding, surgery, tooth removal, nosebleeds, and heavy menstruation. DRUG STUDY ASCORBIC ACID • Vitamin C is a vitamin found in various foods and sold as a dietary supplement. Use to treat scurvy. DRUG STUDY FERROUS SULFATE • Use to treat iron deficiency. DRUG STUDY
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