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INFLAMMATION
QUESTIONS
DR. ABDULLAH AL-SAMAWI
PROFESSOR OF PATHOLOGY
1. Attraction of leukocytes to the site of injury is
enhanced by:
A. Chemotaxis.
B. Transudation.
C. Exudation.
D. Phagocytosis.
E. Cytokines.
1. Attraction of leukocytes to the site of injury is
enhanced by:
A. Chemotaxis.
2. Bradykinin is a mediator of:
A. Pain.
B. Swelling and redness.
C. Vasodilation.
D. Vasoconstriction.
E. Tissue necrosis.
2. Bradykinin is a mediator of:
A. Pain.
3. Fusion of epithelioid cells is lead to formation of:
A. Granuloma.
B. Epithelioid granuloma.
C. Langhans giant cells.
D. Modified macrophages.
E. Abscess.
3. Fusion of epithelioid cells is lead to formation of:
A. Neutrophils.
8. Ulcer means:
A. Lose of interstitial matrix.
B. Dysplasia of lining epithelium.
C. Lose of epithelial surface.
D. Scar formation.
E. Atrophy of the cells.
8. Ulcer means:
B. Reed-Sternberg cells.
10. Chemotaxis include the following except:
A. Soluble bacterial products.
B. Complement system.
C. Thrombin.
D. Chemokines.
E. Leukotriene.
10. Chemotaxis include the following except:
C. Thrombin.
11. Tissue damage caused by the following mediators
except:
A. Lysozomal enzymes.
B. Nitrous oxide.
C. Reactive oxygen species.
D. Histamine.
E. Lysozomal vacuoles.
11. Tissue damage caused by the following mediators
except:
D. Histamine.
12. Chronic inflammation characterized by the following
except:
A. Long duration.
B. Neutrophilic leukocytes accumulation.
C. Angiogenesis.
D. Destruction of tissue.
E. Macrophages.
12. Chronic inflammation characterized by the following
except:
A. Neutrophils.
15. Hotness and redness in inflammation are caused by:
A. Vasoconstriction.
B. Activation of clotting factors.
C. Infarction.
D. Vasodilation and congestion.
E. Clotting factors.
15. Hotness and redness in inflammation are caused
by:
B. Eosinophils.
17. Classical local signs of acute inflammation include
the following except:
A. Pain.
B. Swelling.
C. Hotness.
D. Fever.
E. Redness.
17. Classical local signs of acute inflammation include
the following except:
D. Fever.
18. The following are false about collection of a watery
fluid (serous inflammation) except:
A. The fluid are derived from secretions of mesothelial
cells lining and serum.
B. Formation of fibrinogen.
C. The fluid is due to congestive heart failure.
D. Formation of abscess.
E. The fluid are derived from salivary glands.
18. The following are false about collection of a watery
fluid (serous inflammation) except:
B. Lymphocytes.
20. Inflammation of mucous membrane of upper
respiratory tract with free fluid discharge is known as:
A. Catarrhal inflammation.
B. Serous inflammation.
C. Fibrinous inflammation.
D. Suppurative inflammation.
E. Bacterial tonsillitis.
20. Inflammation of mucous membrane of upper
respiratory tract with free fluid discharge is known as:
A. Catarrhal inflammation.
21. The right lower quadrant abdominal pain associated
with acute inflammation in acute appendicitis is
predominantly the result of the formation of which two
mediators.
A. Complement C3b and IgG.
B. IL-1 and TNF.
C. IL-6 and PAF.
D. Histamine and serotonin.
E. Prostaglandin and bradykinin.
21. The right lower quadrant abdominal pain associated
with acute inflammation in acute appendicitis is
predominantly the result of the formation of which two
mediators.
A. Macrophage.
25. Neutrophils form part of an alveolar exudate in an
acute pneumonia as a result of the actions of all of the
following factors except:
A.Complement.
B. Bradykinin.
C. Soluble bacterial products.
D. Leukotriene.
E. Interleukine.
25. Neutrophils form part of an alveolar exudate in an
acute pneumonia as a result of the actions of all of the
following factors except:
B. Bradykinin.
26. Increased vascular permeability mediated by the
following except:
A. Histamine.
B. Serotonin.
C. Leukotrienes.
D. PAF.
E. Tumor necrotizing factor.
26. Increased vascular permeability mediated by the
following except:
A. Mycobacterium leprae.
29. A lesion which appears mainly as a loss of an
epithelial surface in a localized area is known as:
A. Abscess.
B. Serositis.
C. Granuloma.
D. Ulcer.
E. Dysplasia.
29. A lesion which appears mainly as a loss of an
epithelial surface in a localized area is known as:
D. Ulcer.
30. The appearance of fibrin with numerous neutrophils
on the pericardial surface is most characteristic for:
A. Bacterial infection.
B. Metastatic carcinoma.
C. Acute myocardial infarction.
D. Mycobacterial infection.
E. Acute viral infection.
30. The appearance of fibrin with numerous neutrophils
on the pericardial surface is most characteristic for:
A. Bacterial infection.
31. Which statement regarding macrophages is incorrect:
A. Macrophages survive much longer than neutrophils.
B. Mycobacterium tuberculosis.
33. A previously healthy 47 year old woman dies suddenly
after an illness lasting only a couple of days. The high
power microscopic section from lung demonstrates
extensive neutrophilic alveolar exudates. What is the
most likely etiology for this disease:
A. Influenza A virus.
B. Mycobacterium tuberculosis.
C. Str. pneumonia.
D. Pneumocystis carinii.
E. All of above.
33. A previously healthy 47 year old woman dies suddenly
after an illness lasting only a couple of days. The high
power microscopic section from lung demonstrates
extensive neutrophilic alveolar exudates. What is the
most likely etiology for this
disease:
C. Str. pneumonia.
34. A 45 year old male has had gradual enlargement of
the right parotid gland for several months. A calculus
(stone) is found in the salivary gland duct. The best
diagnosis, based upon the appearance of extensive
mononuclear cell infiltrates in the gland is:
A. Gummatous necrosis.
B. Cryptococcus neoformans infection.
C. Chronic sialadenitis.
D. Gangrene.
E. Acute sialadenitis.
34. A 45 year old male has had gradual enlargement of
the right parotid gland for several months. A calculus
(stone) is found in the salivary gland duct. The best
diagnosis, based upon the appearance of extensive
mononuclear cell infiltrates in the gland is:
E. Acute sialadenitis.
35. Vasodilation mediated by which of the following
compounds would be useful to prevent additional
ischemic tissue damage:
A. Thromboxane.
B. Complement C3b.
C. Nitric oxide.
D. Tumor necrosis factor.
E. Chemokines.
35. Vasodilation mediated by which of the following
compounds would be useful to prevent additional
ischemic tissue damage:
C. Nitric oxide.
36. Which of the following mediatores enhances
phagocytosis of bacteria by neutrophils.
A. Lysozyme.
B. Interleukine-5.
C. Bradykinin.
D. Nitorus oxide.
E. PAF.
36. Which of the following mediatores enhances
phagocytosis of bacteria by neutrophils.
A. Lysozyme.
37. Which of the following mediators is response for pain
of inflammation that is relieved by aspirin.
A. Histamine.
B. Interleukine-1.
C. Prostoglandin.
D. Complment.
E. TNF.
37. Which of the following mediators is response for pain
of inflammation that is relieved by aspirin.
C. Prostoglandin.
38. Which of these cells are seen in large numbers in a
subacute (intermediate) ischemic infarct.
A. Foreign body giant cells.
B. Neutrophils.
C. Mast cells.
D. Fibroblasts.
E. Eosinophils.
38. Which of these cells are seen in large numbers in a
subacute (intermediate) ischemic infarct.
B. Neutrophils.
39. Which of these cells release histamine:
A. Mast cells.
B. Neutrophils.
C. Plasma cells.
D. Langhans giant cells.
E. NK cells
39. Which of these cells release histamine:
A. Mast cells.
40. The pain and tenderness along with the red
discoloration of the skin seen in a 29 year old male who
was at the beach all day and who now is in the early stage
of sunburn is most likely to be mediated by:
A. Complement C3.
B. Bradykinin.
C. Interleukin-1.
D. C-reactive protein.
E. Histamine.
40. The pain and tenderness along with the red
discoloration of the skin seen in a 29 year old male who
was at the beach all day and who now is in the early stage
of sunburn is most likely to be mediated by:
B. Bradykinin.
41. Fever is mediated by the following except:
A. Interlukine-1.
B. Interlukine-6.
C. Histamine.
D. Tumor necrotizing factor.
E. Prostoglandin.
41. Fever is mediated by the following except:
C. Histamine.
42. Outcomes of acute inflammation includes the
following except:
A. Complete resolution.
B. Scarring.
C. Progressive to malignancy.
D. Abscess formation.
E. Progressive to chronic inflammation.
42. Outcomes of acute inflammation includes the
following except:
C. Progressive to malignancy.
43. Chronic specific inflammation characterized by:
A. Activation of humoral immunity.
B. Formation of IG.
C. Granuloma formation.
D. Suppurative inflammation.
E. None of above.
43. Chronic specific inflammation characterized by:
C. Granuloma formation.
44. Macrophage functions includes the following except:
A. Killing tumor cells.
B. Lysosomal enzymes secretion
C. Phagocytosis.
D. Ig production.
E. Antigen presenting cells.
44. Macrophage functions includes the following except:
D. Ig production.
45. Phagocytosis of bacteria is enhance by:
A. Histamine production.
B. Opsonin receptors.
B. Bradykinin secretion.
D. Gamma interferon.
E. IgA secretion.
45. Phagocytosis of bacteria is enhance by:
B. Opsonin receptors.
46. The following statement about leukocytosis are
correct except:
A. Eosinophilia can be is seen in allergic reaction.
B. Monocytosis can be seen in TB.
C. Neutrophilia can be seen in acute viral infection.
D. Neutropenia can be seen in typhoid fever.
E. Eosinophilia can be seen in parasitic infection.
46. The following statement about leukocytosis are
correct except:
D. Staphylococcus aureus.
49. Cytokines are polypeptide products of many cells
mainly:
A. Activated fibroblast and mast cells.
B. Activated leukocytes and macrophages.
C. Plasma cells and basophils.
D. Red blood cells and activated platelets.
E. Cytotoxic cells and stem cells.
49. Cytokines are polypeptide products of many cells
mainly:
D. Smooth muscles.
54. The following are false about the non dividing cells
except:
A. Hematopoietic cells.
B. myocardium.
C. Liver
D. Pancreas.
E. Smooth muscle cells.
54. The following are false about the non dividing cells
except:
B. Myocardium.
55. Regarding the stem cells which statement is incorrect:
A. Undifferentiated cells.
B. Have self renewal capacity.
C. Part of new field of regenerative medicine.
D. Embryonic stem cells is less differentiated.
E. Play role in regenerative medicine.
55. Regarding the stem cells which statement is
incorrect:
D. Surgical incision.
58. Secondary healing characterized by the following
except:
A. Large tissue defect.
B. Large amount of granulation tissue.
C. Less fibrosis.
D. Wound contracture.
E. Most of the above.
58. Secondary healing characterized by the following
except:
C. Less fibrosis.
59. Callus formation is seen in:
A. Wound healing.
B. Fracture healing.
C. Abscess healing
D. Healing of infarction.
E. Neural tissue healing.
59. Callus formation is seen
in:
B. Fracture healing.
60. Corticosteroides have worse effect in:
A. Treatment of autoimmune disease.
B. Treatment of hypersensitivity reactions.
C. Healing process.
D. Contact dermatitis.
E. Treatment of asthmatic patient.
60. Corticosteroides have worse effect in:
C. Healing process.
61. Keloid is:
A. Aberration of bone healing.
B. Scar formation.
C. Destruction of joints.
D. Granulation tissue.
E. Formation of excessive amount of collagen.
61. Keloid
is: