Documenti di Didattica
Documenti di Professioni
Documenti di Cultura
Orthopaedics
• 1990’s
• More selective fixation
(Border et al)
• Greater physiological
understanding
Progress
• 1993 – first literature reporting
successful use of temporary ex-fix
• 1940’s
• Phase 1 – Laporotomy stop bleeding
• Phase 2 – Resuscitate
• Phase 3 – Definitive surgery + closure
Gen Surgery Damage Control
• 1940’s
• Phase 1 – Laporotomy stop bleeding
• Phase 2 – Resuscitate
• Phase 3 – Definitive surgery + closure
SIRS – systemic inflammatory response syndrome
CARS – counter reg’ anti-inflam’ response syn’
MODS – Multiple organ dysfunction syndrome
ARDS – Adult respiratory distress syndrome
First Hit
• Initial massive injury and shock
• Systemic Inflammatory Syndrome
• MØ, LØ, NK Cells, IL’s, Complement
• Endothelial permeability lungs
• ARDS, MODS/MOF
ARDS
What’s wrong with IL-9!
Second Hit
• Restimulate / Hyperstimulate
inflammatory system
• Shock
• Head/neck
• Face
• Chest
• Abdo
• Extremity
• External
Injury Severity Score
Abreviated Injury Scale (threat to life)
• Minor 1
• Moderate 2
• Serious 3
• Severe 4
• Critical 5
• Unsurvivable 6
Injury Severity Score
• Highest AIS for each region
• Top 3 used
• Scores squared and added
• Out of 75
• Major Trauma ISS>15
• Any region scoring 6 = ISS 75
Injury Severity Score
• Correlates with Mortality, morbidity, LOS
• 15-44 ISS 40
• 45-64 ISS 29
• 65 - ISS 20