Circulatory System •Genetics •Pollution •Smoking •Substance abuse Under Direct Control •Food choices •Activity and exercise Smoking Negative effects on circulatory system ◦ Nicotine causes blood vessels to constrict – heart has to pump more strongly to push blood through the vessels ◦ Can interfere with heart contraction and relaxation Substance Abuse Negative effects on circulatory system ◦ Stimulants damaged heart muscle ◦ Can cause blood clots – impair circulation Food Choices Negative effects on circulatory system ◦ Saturated and trans fat deposit fatty substances inside blood vessels – restrict blood flow ◦ Foods in high salt and sugar can raise blood pressure Activity and Exercise Negative effects on circulatory system ◦ Too little activity and exercise can stress the heart – heart contractions are less effective and blood flow is reduced ◦ Too little exercise can cause unhealthy weight gain – adds more stress to the heart Circulatory Illnesses that Disturb Homeostasis and Impair Function Arrhythmia Description ◦ A heartbeat with an irregular rate or rhythm ◦ Occurs if the electrical signal is delayed or blocked ◦ Causes – smoking, drugs, caffeine, alcohol, stress or inherited Symptoms ◦ Fast, slow, or irregular heartbeat ◦ Anxiety ◦ Weakness ◦ Fainting ◦ Shortness of breath ◦ Chest pain Arrhythmia Tests ◦ Electrocardiogram (ECG) – a tool that measures electrical activity in the heart Treatment ◦ Medication to restore normal heart rate and rhythm ◦ Pacemaker – a device that sends electrical signals to the heart Leukemia Description ◦ Cancer of the blood or bone marrow – large numbers of abnormal cells are produced ◦ Cells (typically white blood cells) crowd other blood cells so that blood cannot carry out its normal functions ◦ Cause is unknown – genetic factors, and environment may play a role Symptoms ◦ Fatigue ◦ Frequent infection ◦ Weight loss ◦ Swollen lymph nodes Leukemia Tests ◦ Blood counts to determine number of white blood cells ◦ Blood and bone marrow are examined with a microscope for cancer cells Treatment ◦ Chemotherapy and radiation ◦ Bone marrow transplant Stroke Description ◦ Brain does not receive enough blood and brain cells start to die ◦ 80% are caused by a clot blocking an artery ◦ 20% are caused by broken blood vessels in or around the brain – aneurism ◦ Paralysis and impaired mental function often occur Symptoms ◦ Weakness ◦ Speech and vision problems ◦ Headache ◦ Dizziness Stroke Tests ◦ Check for vision, movement and speech problems ◦ Angiography – a technique that x-rays the inside of blood vessels to find blocked arteries Treatment ◦ Must be treated right away ◦ Clot busters – medication that destroy clots ◦ Angioplasty – procedure that opens up blocked arteries ◦ Post-stroke therapy – help recover some physical and mental function Atherosclerosis Description ◦ Condition where arteries narrow or become blocked by plaque that limits blood flow to the body ◦ Causes ◦ High fat diet ◦ Smoking ◦ Genetic factors Symptoms ◦ Shortness of breath, chest tightness and fatigue ◦ Heart attack – when an artery that feeds the heart oxygen is blocked ◦ Known as the “silent killer” – many people have no symptoms until a heart attack occurs Atherosclerosis Tests ◦ Physical exam to check for weak pulse – a sign of a narrowed or blocked artery ◦ Blood tests – to check for high levels of certain fats (i.e. cholesterol) Treatment ◦ Coronary bypass surgery – surgically rerouting blood flow around a blockage ◦ Angioplasty – to open a blocked artery