Documenti di Didattica
Documenti di Professioni
Documenti di Cultura
Objectives:
B. Epidemiology:
C. Clinical manifestations:
E. Treatment:
1. 5% permethrin cream
2. 1% lindane (not in pregnant women)
3. Anti-pruritics as needed
LICE
LICE
A. Etiology:
B. Epidemiology:
C. Clinical manifestations:
E. Treatment:
1. 1% permethrin
2. 0.5% malathion
3. 1% lindane - more toxic and must apply a second dose 1 week later
- does not kill nits
- not in pregnant women
4. Comb out nits after treatment
HUMAN PAPILLOMAVIRUS (HPV)
• Papovavirus
• Most common viral STD
• ds DNA virus of 7.9 kB
• Entire DNA sequence is
known
HPV TYPES
Defined by 10% difference in DNA sequence (L1 gene)
• CONDYLOMA LATUM-SYPHILIS
• MOLLUSCUM CONTAGIOSUM
• LICHEN PLANUS
CIN II
CERVICAL CANCER
CONVENTIONAL
Cervical biopsy:
CIN I – mild dysplasia – usually spontaneously regresses
CIN II – moderate dysplasia - treat
CIN III – severe dysplasia – treat
Carcinoma – in-situ – treat
Invasive cervical cancer – treat
CERVICAL CANCER
SCREENING METHODS
• OBSERVATION
• CRYOTHERAPY-LASER
• CONE BIOPSY-SURGERY
• RETINOIDS??
PROPHYLACTIC VACCINES
AGAINST HPV
Utilizing in-vitro capsid production:
(VLPs – Virus-Like Particles)
No infectious potential
ACIP. Recommendations for the use of quadrivalent HPV vaccine. Available at:
http://www.cdc.gov/nip/recs/provisional_recs/hpv.pdf. Accessed December 19, 2006.
ACIP Recommendations (cont.)
Quadrivalent HPV vaccine is not recommended for
use in pregnancy.
ACIP. Recommendations for the use of quadrivalent HPV vaccine. Available at:
http://www.cdc.gov/nip/recs/provisional_recs/hpv.pdf. Accessed December 19, 2006.