Pansitopenia

Dr. Isbandiyah, SpPD

 Definition
Cytopenia is a reduction in the number of
each type of peripheral blood cell.
A reduction in all 3 types of cellular
components in peripheral blood is termed
pancytopenia and this involves anaemia,
neutropenia, and thrombocytopenia.
Causes of pancytopenia
Causes of aplastic anemia
TYPE BM Blasts% Peripheral Auer Rods Monocytes > Ringed
blood blasts 1000 /uL Sideroblasts
% >15%

RA <5 <1 No No No

RAS <5 <1 No No Yes

RAEB 5-20 <5 No No +-

CMML <20 <5 No Yes +-

RAEB-T 21-30 >5 +- +- +-