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NBME 18 - DOWNLOAD

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Pulmonary artery hypertension (PAH) results from increase in
release of endothelin-1. PAH is a consequent of pulmonary
fibrosis. Bosentan is a medication frequently used to treat PAH
through antagonization of the endothelin receptor.
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Meningioma: usually presents with localized neurological deficits since it normally has a mass
effect and pushes on the cerebral hemispheres. It also is described on imaging as a mass with a
tail, since it is sprouting from the meninges.
Schwannoma: is classically located in the cerebellar-pontine junction, and therefore intratentorial,
and also will come with other s/s of hearing loss, tinnitus, ect.
Metastasis: is typically 2+ lesions, not just the one, but this could have easily been mets as well,
its just that astrocytoma is a better fit for the clinical picture presented.

Astrocytomas are single lesions that are often in the frontal lobe, presenting with
personality changes therefore, and butterfly from lobe to the other through the
corpus callosum.

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Musculocutaneous N.

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Dx is cryoglobulinemia secondary to hepatitis C. And what do
cryoglobulins do to the kidney? Cause nephrotic syndrome by
settling in the kidney and causing an immune response. So,
whenever you have circulating immune complexes, that is
always a type III hypersensitivity reaction
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Necator americanus/ ancylostoma duodenale

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To get 3 digit score, use following method:


Whatever number of questions you get correct out of 200.. Multiply by 1.4 - 1.42..
For eq. If you get 175 out of 200 the score is 245 - 249 roughly.

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