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Presented by:
Earliest cough
histopathological
breathlessness
response is a histiocytic
infiltrate in the lung wheezing
parenchyma an increased peripheral
eosinophil count.
Acute eosinophilic
exudate within the symptom is
lungs unchanged
Correlation of the clinical features with the
lung functions and histopathology (Contd)
Serology:
CBC: Striking eosinophilia >3000/m and
may rise as high as 80,000/m
ESR: High
Investigations
Chest Imaging:
Chest x-Ray:
Usually normal
The main radiological features include reticulo-
nodular shadows more in the mid to lower zones and
miliary mottling .
CT Chest:
Features of bronchiectasis, air trapping,
lymphadenopathy, cavitation, consolidation or
pleural effusions in addition to the miliary mottling
and interstitial shadows
Investigations
Chest x-Ray of TPE CT scan of chest
Investigations
Spirometry
BAL
BAL from acute untreated TPE revealed a striking
eosinophilic alveolitis.
Differential diagnosis
.
Prevention
.
Tropical pulmonary eosinophilia
(TPE) is a syndrome of wheezing,
fever and eosiniphilia seen
predominantly in the Indian
subcontinent.