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Biopotentials
Excitable cells
Non-excitable Cells
Excitable Cells:
Electrochemical activities of certain class of cells produce changes in electrical potential difference between the inter and extra
cellular medium and generates all or nothing electrical pulse (action potential)
Nerve cells (sensory , motor and processing)
Motor cells (kind of actuators controlled by Pulse modulation )
Glandular cells ( also a Kind of actuator controlled by Pulse modulation)
brain stem
The part of the brain that connects the spinal cord to the forebrain and cerebrum.
cerebellum
Part of the hindbrain in vertebrates. In humans it lies between the brainstem and
the cerebrum, and plays an important role in sensory perception, motor output,
balance, and posture.
spinal cord
A thick, whitish cord of nerve tissue that is a major part of the central nervous
system. It extends from the brain stem through the spine, with nerves branching off
to various parts of the body.
cerebrum
In humans it is the largest part of the brain and is the seat of motor and sensory
functions, as well as the higher mental functions such as consciousness, thought,
reason, emotion, and memory.
Brain Stem
The brain stem is connected to the underside of the brain. It consists of the midbrain, pons, and medulla. The midbrain is
found in between the hindbrain and the forebrain. It regulates motor function and allows motor and sensory information to
pass from the brain to the rest of the body. The pons houses the control centers for respiration and inhibitory functions. The
medulla also helps regulate respiration, as well as cardiovascular and digestive functioning.
The cerebrum, or the top portion for the brain, is the seat of higher-level thought. It is comprised of two hemispheres, each
controlling the opposite side of the body. Each of these hemispheres is divided into four separate lobes:
the frontal lobe, which controls specialized motor control, learning, planning, and speech;
the parietal lobe, which controls somatic or voluntary sensory functions;
the occipital lobe, which controls vision;
the temporal lobe, which controls hearing and some other speech functions.
Cerebellum
In humans, the cerebellum plays an important role in motor control,
and it may also be involved in some cognitive functions such as
attention and language as well as in regulating fear and pleasure
responses
The limbic system is the emotional brain made of deep gray Cingulate gyrus is involved with shifting thoughts, expressing
matter structures linked together by the fornix. The fiber tracts emotions through gestures and resolving frustration.
have the appearance of oval fibers and looks like the corpus
callosum but its not the same. The limbic system also includes The amygdala (fear and its sympathetic response) and
certain structures of the diencephalon: the anterior thalamus hippocampus (form and retrieve memories) reside very close
and hypothalamus. together.
1% 80%
2% 2%
Ca++?
Propagation of Action Potential :
Hodgkin Huxley Model:
Axon Model
Voltage Clamp Measurement:
Hodgkin Huxley Model: Continued
Hodgkin Huxley Model: Continued
Channels consists of Gates:
Individual can be permissive or non permissive
n n
Steady state
Time constant
similarly
n
Hodgkin Huxley Model: Continued
Hodgkin Huxley Model: Continued
Hodgkin Huxley Model: Continued
t t
t
Note cable equation
Recording of Bioelectrical Phenomena:
Body surface electrodes measurements are used
Electrocardiogram (ECG)
Electroencephalogram (EEG)
Electroneurogram (ENG)
Electromiogram(EMG)
Electroretinogram (ERG)
Electrogastrogram(EGG)