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CASE REPORT
BRONCHOPNEUMONIA
DENGUE
HEMORRHAGIC
FEVER
Compiled By
Nia Stefani Tambunan Supervisor
(120100093) dr.Hj. Tiangsa br Sembiring,
M.Ked (Ped), Sp. A (K)
Verra Anindya S.R
(120100022) 1
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INTRODUCTION
2
Caused by
INTRODUCTION a variety
of etiology
such as
The main bacteria,
cause of
Broncho
viruses,
death, fungi, and
especially in foreign
children
under five pneumo bodies
years.
nia
3
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LITERATURE REVIEW
4
WHAT IS
BRONCHOPNEUMONIA
Pneumonia is
an The infection
inflammation causes
of the lungs inflammation
Bronchopneumon caused by a in the alveoli
ia is a type of variety of in the lungs,
pneumonia etiology such causing the
as bacteria, alveoli to fill
viruses, fungi, with pus or
and foreign fluid
bodies
5
EPIDEMIOLOGY
Source: UNICEF,
7
EPIDEMIOLOGY
64.73 65.09 64.81
Resolution Stadium:
neutrophil degeneration,
loose of fibrine, bacterial
CLASSIFICATION
Clinical and Pathog Morphology
Epidemiology ens
Community- Typical Lobaris
acquired peumonia
Hospital-acquired Atypical Bronchopneu
pneumonia/ monia
nosocomial
pnuemonia
Aspiration Interstitial
pneumonia
Immmunocompromi
sed pneumonia
14
WHAT ARE THE SYMPTOMS?
Fever
Cough
Shortness of breath
Chest pain
Rapid breathing
sweating
Shaking chills
Malaise
fatique Age Breaths per
Confusion or delirium minute
<2 months age >60 breaths per
minute
15
2-12 months age >50 breaths per
TEST AND DIAGNOSIS
Clinical symptoms
Physical exam : fever, lung sound, percussion,
crackles, retraction, dullness, etc
Laboratorium: complete blood count (CBC)
number of WBC elevated bacterial infection
Chest x ray
Sputum test
16
TREATMENT OPTIONS
Viral bronchopneumonia:
normally doesnt require
medical treatment and
improves on its own in one
to two weeks
Bacterial
bronchopneumonia:
antibiotic
17
Recommendation 1
Children with fast breathing pneumonia with no chest
indrawing or general danger sign should be treated with oral
amoxicillin: at least 40 mg/kg/dose twice daily (80 mg/kg/day)
for 5 days. In areas with low HIV prevalence, give amoxicillin
for three days.
18
Recommendation 2
Children age 2-59 months with chest indrawing pneumonia
should be treated with oral amoxicillin: at least 40
mg/kg/dose twice daily for five days
19
Recommendation 3
Children aged 259 months with severe pneumonia should be
treated with parenteral ampicillin (or penicillin) and
gentamicin as a first-line treatment.
Ampicillin: 50 mg/kg, or benzyl penicillin: 50 000 units per
kg IM/IV every 6 hours for at least five days
Gentamicin: 7.5 mg/kg IM/IV once a day for at least five
days
Ceftriaxone should be used as a second-line treatment in
children with severe pneumonia having failed on the first-line
treatment.
20
Recommendation 4
Ampicillin (or penicillin when ampicillin is not
available) plus gentamicin or ceftriaxone are
recommended as a first-line antibiotic regimen for
HIV-infected and -exposed infants and for children
under 5 years of age with chest indrawing
pneumonia or severe pneumonia.
For HIV-infected and -exposed infants and for
children with chest indrawing pneumonia or severe
pneumonia, who do not respond to treatment with
ampicillin or penicillin plus gentamicin, ceftriaxone
alone is recommended for use as second-line
treatment.
21
Recommendation 5
Empiric cotrimoxazole treatment for suspected
Pneumocystis jirovecii (previously Pneumocystis
carinii) pneumonia (PCP) is recommended as an
additional treatment for HIV-infected and -exposed
infants aged from 2 months up to 1 year with chest
indrawing or severe pneumonia.
Empirical cotrimoxazole treatment for Pneumocystis
jirovecii pneumonia (PCP) is not recommended for
HIV-infected and -exposed children over 1 year of
age with chest indrawing or severe pneumonia.
22
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CASE REPORT
23
CASE REPORT
AKZ, a 1years 17 days old girl
BW: 6 kg BH: 59 cm
Main complain :
Shortness of breath since 7 days ago . Not
associated with activity or weather, occurs
after coughing. Restlessness due to short of
breathing at night (+). Grunting (+). History of
shortness of breath (-). Wheezing (-). History
of choking (-). Cyanosis (-). 24
CASE REPORT
Cough, 2 days ago. Sputum (-). Hemoptysis
(-). History of exposure with people who have
lung disease (+)
Fever, 7 days ago. Characteristic of fever is
high (>38o C), responded to antipyretic drug
but it increase again after 2 hours. Convulsion
(-). Shivering (-)
Flu (-)
Vommiting (-), nausea (-) 25
CASE REPORT
History of medication : azithromycin,
paracetamol, ibuprofen, L-Bio, Lasal*
(salbutamol), Univir* (acyclovir), valproate acid
(since 8 months)
History of previous disease: ventricular septal
defect (VSD) (since 1 month old), epilepsy (since
8 months old)
History of family : none
26
History of pregnancy: during pregnancy mother is 25
y.o. Hypertension (-). DM (-). Fever (-). Medicine
consumption (-). Ante natal care during pregnancy (+)
History of birth :Birth was assisted by a doctor.
Cesarean section with indication post-term pregnancy
and cried immediately after birth. Cyanosis (-). BW:
3500 gram. Body length 40 cm. head circumference (?)
History of feeding :
1. 0 6 months : formula milk freq: 4-6 x/day
2. 6 7 months : strained porridge + formula milk,
freq: 2- 4 x/day
3. 7 months now : smooth porridge + formula milk,
27
History of growth and development: the patient
can not stand, sit, and talk until now
History of immunization: according to patients
mother, immunization was complete except measles
vaccine
28
Physical Examination
Present Status:
Sensoriu : CM (GCS 14 = E4V4M6) BW : 6,1 Kg
m
HR : 140 x/i reguler, murmur BL : 59 cm
(+) systolic grade III/6
Linea Mid Claviculari
ICS III-IV
Temp : 38,5oC BW/A : - 3 SD < Z score < -2
SD
RR : 52 x/i BH/A : Z score < 3 SD
BW/BH : - 2 SD < Z score < -1
SD
Anemic (-), icteric (-), dyspnea (+), cyanosis (-), oedema (-/-)
29
Localized Status:
Head : Eye: Light reflex (+/+), isochoric pupil (R:3mm ,L: 3 mm),
pale inferior conjungtival palpebra(-/-), palpebra edema (-/-)
Ear: Both ear lobe in normal morphologic
Nose : Septum deviation (-), normal morphologic.
Mouth: Cleft palate (+), Cyanosis (-)
Neck : Lymph node enlargement (-).
Thorax : Symmetrical fusiform, epigastric retraction (+),
- HR: 110 bpm, regular, murmur (+) systolic grade III/6 linea
midclavicula sinistra (LMCS) ICS III-IV
- RR: 52 bpm, regular, ronchi (+/+), bronchial, wheezing
(-/-).
30
Localized Status:
31
Laboratory Finding :
Complete Blood Analysis (28-12-2016 )
Count B loodCell (CBC) AGDA
Haemoglobin : 10,5 g/dl PH : 7,38
Hematocryte : 32,5 % PCO2 : 48 mmHg
Leukocyte : 17,150 PO2 : 44,2 mmHg
103/uL
Thrombocyte : 226 103/uL HCO3 : 27,3 mmol/L
Eosinophil : 4,3 % Total CO2 : 24
Basophil : 0,9 % BF : 2,5 mmol/L
Limphocyte : 19 % SaO2 : 86,6 %
Monocyte : 10,9 %
Neutrophil : 64,9 %
Electrolite Methabolism
Natrium : 132 mmol/L Blood glucose : 118 mg/dL
Kalium : 4,4 mmol/L
Chloride : 101 mmol/L 32
33
Differensial Diagnosis:
1. Bronchopneumonia + VSD + Palatoschisis + epilepsy
+ umbilical hernia
2. Tuberculosis + Atrial septal defect (ASD) +
Palatoschisis + epilepsy+ umbilical hernia
3. Fungal lung + Patent Ductus Arteriosus (PDA) +
Palatoschisis + epilepsy+ umbilical hernia
Working Diagnosis :
Bronchopneumonia + Ventricular Septal defect (VSD) +
Palatoschisis + Epilepsy + Umbilical Hernia 34
Therapy :
IVFD D5% NaCL 0,225% 25 gtt/I
Inj. Ampicillin 300 mg/6h/IV
Inj. Gentamicin 40 mg/24h/IV
Paracetamol drop 3 x 60 mg (0,6 cc)
Diet F75 100 cc/3 hour + 2 cc mineral mix/oral/NGT
Valproat acid syr 2 x 1 cc
Inj. Furosemide 6 mg/12h/IV
Spironolactone 2 x 6.25 mg
Folat acid 1 x 1 mg
Vit. B complex 1 x 1 tab
Vit. C 1 x 50 mg
35
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FOLLOW UP
36
29thof December 2016
S : Dyspnea (+), cough (+), fever (+)
O : Sens : Compos mentis GCS 14 (E3M6V5), Temperature : 38C BB: 6,1 Kg
Head
Eye : Light reflex (+/+), isochoric pupil (R:3mm ,L: 3 mm), pale inferior
palpebral conj. (-/-)
Ears : Both ear lobe in normal morphologic.
Nose : Septum deviation (-), normal morphologic.
Mouth : Cleft palate/Palatoschisis (+), Cyanosis (-)
Neck : Lymph node enlargement (-).
Thorax : Symmetrical fusiform, epigastricretraction (+), HR: 120 x/i, regular,
murmur (+) systolic grade III/6 LMCS ICS III-IV RR: 60x/i, regular,
ronchi (+/+), bronchial (+/+), wheezing (-/-). Stridor (-/-)
Abdomen : Symmetrical, Soepel, peristaltic (+) normal, hepar, lien :
unpalpable, Umbilical hernia (+)
Extremities: BP: cant be measured, Pulse 120 x/i, regular,adequate p/v,felt
warm, CRT 3, cyanosis (-), clubbing finger (-), oedema (-/-).
A : Bronchopneumonia + Ventricular septal defect (VSD) + palatoschisis +
umbilical hernia + epilepsy
P :
IVFD D 5 % NaCL 0,225 % 25gtt/I
Inj. Ampicillin 300 mg/6h/IV
Inj. Gentamicin 40 mg/24h/IV
Paracetamol drop 3 x 60 mg (o,6 cc)
Diet F100 100 cc/3 hour + 2 cc mineral mix/oral/NGT
Valproat acid 2 x 1 cc
30-31thof December 2016
S : Dyspnea (+), cough (+), fever (+)
O : Sens : CM Temp : 37,8oC BW: 5,9 Kg
Head : old man face (-), prominent cheekbones (-), Head Circumference : 40 cm
(microcephaly),
Eye : Light reflex (+/+), isochoric pupil (R:3mm ,L: 3 mm), pale inferior palpebral
conj. (-/-).
Nose : Normal
Ear : Normal
Mouth : Palatoschisis
Thorax : Symmetrical fusiform, epigastricretraction (+), HR: 120 x/i, regular,
murmur (+) systolic grade III/6 line midclaviculasinistra ICS III-IV RR: 50x/i,
regular, ronchi (+/+), bronchial (+/+), wheezing (-/-). Stridor (-/-)
Abdomen : Symmetrical, Soepel, peristaltic (+) normal, hepar, lien : unpalpable,
Umbilical hernia (+)
A : Bronchopeumonia + Small VSD + Palatoschisis + microcephaly
+ Epilepsy
P :
IVFD D 5 % NaCL 0,225 % 25gtt/I
Inj. Ampicillin 300 mg/6h/IV
Inj. Gentamicin 40 mg/24h/IV
Paracetamol drop 3 x 60 mg (o,6 cc)
Diet F100 100 cc/3 hour + 2 cc mineral mix/oral/NGT
Valproat acid 2 x 1 cc
Vitamin B-Complex 1 x 1 tab
Vitamin C 1 x 100 mg
Inj. Furosemide 6 mg/12h/IV
Spironolactone 2 x 6,25 mg
Planning:
Blood culture and sensitivity
Consultation to the departement of nutrition about diet high
calory with fluid retriction
Table 2. Laboratorium Test Result (31-12-2016) AGDA Electrolite
PH 7,38 7,37-7,45 mmHg
pCO2 49,0 33-44 mmHg
pO2 43,20 71-104 mmHg
HCO3 28,4 22-29 mmol/L
BE 2,7 (-2)-3 mmol/L
O2 sat 71,2 94-98 %
Na/K/CL/C 134/4,81/98/0,5 135-155/3,1-5,1/96-106
a
Ht 33,70 37-41%
Eye : Light reflex (+/+), isochoric pupil (R:3mm ,L: 3 mm), pale inferior palpebral
conj. (-/-).
Nose : Normal
Ear : Normal
Mouth : Palatoschisis
Thorax : Symmetrical fusiform, retraction (+), HR: 132 x/i, regular, murmur (+)
systolic grade III/6 line mid clavicula sinistra ICS III-IV RR: 52x/i, regular,
Eye : Light reflex (+/+), isochoric pupil (R:3mm ,L: 3 mm), pale inferior palpebral
conj. (-/-)
Nose : Normal
Ear : Normal
Mouth : Palatoschisis
Thorax : Symmetrical fusiform, retraction (-), HR: 124 x/i, regular, murmur (+)
systolic grade III/6 line midclaviculasinistra ICS III-IV RR: 40x/i, regular,
Eye : Light reflex (+/+), isochoric pupil (R:3mm ,L: 3 mm), pale inferior palpebral
conj. (-/-).
Nose : Normal
Ear : Normal
Mouth : Palatoschisis
Thorax : Symmetrical fusiform, retraction (-), HR: 140 x/i, regular, murmur (+)
systolic grade III/6 line midclaviculasinistra ICS III-IV RR: 38x/i, regular,
DISCUSSION
57
DISCUSSION
Theory Cases
Definition: -
Pneumonia is an inflammation of the lungs
caused by a variety of etiology such as
bacteria, viruses, fungi, and foreign bodies.1
Pneumonia is a form of acute respiratory
infection that affects the lungs
Epidemiology: The patient was a girl, 1 year 17 days with
In Indonesia, pneumonia is the leading diagnose bronchopneumonia.
cause of death, especially in infants 1-4
years.3 Prevalence of pneumonia from 2007
until 2009 among children between 1-4
years is more common than infants (<1
years) and percentage of deaths among
children under-five in 2015 in Indonesia is
15-19%.
58
DISCUSSION
Theory Cases
Risk factor: In this case, the patient is 1 years 17 days old. Infants from
- Young age birth to age two are at risk for pneumonia, as are indiviuals age
- Lack of 65 or older. Their immune system are weak rather than adult.
immunization
- Malnutrition Patient have a small ventricular septal defect (VSD) since 1
- Crowded months of age that predispose to bronchopneumonia. Most
- Pollution previous reports identified CHD as an underlying cause of
- Low birth weight recurrent pneumonia i.e. when there are two or more
- Vitamin A deficiency pneumonia episodes in a year.
Specific risk factors:
Lung disease
Anatomic problems
GERD
Some congenital
heart disease (CHD)
etc
59
DISCUSSION
Theory Cases
Etiology: multiple Routine laboratory test may be helpful for diagostic purpose,
microbes, predominantly A complete blood count (CBC) may show a high white blood
viruses and bacteria, cell count, indicating the presence of bacterial infection.
cause pneumonia in Leucopenia may suggest viral pneumonia. Blood culture are
infant and children ( 3 positive in 5-14% of cases.
months 5 years): In this patient we found that Leukocyte 17.150 (N:6.000-
RSV, PIV, Influenza, 17.000) (28-12-2016), and the leukocyte increase again
Human meta become 19.360 (31-12-2016) and 20.840 (1-1-2017), High
pneumovirus, white blood cell count may suggest bacterial infection. We
adenovirus, rhinovirus have do the culture test, but because of lack of blood, the
Streptococcus result is negative.
pneumonia
Haemophilus aureus
Staphylococcus aureus
Mycoplasma
pneumonia
Mycobacterium
tuberculossis
60
DISCUSSION
Theory Cases
Diagnostic: In this patient, we found:
Symptoms: Fever : 38,5oC since 7 days ago, respons to antipyretic drug
Fever but increase again.
Cough Rapid breathing : 52 x/I (tachypnea: >40x/I for 12 months-5
Shortness of breath years)
Chest pain Cough with sputum (but patient can not cough up the
Rapid breathing sputum in her chest)
sweating
Shaking chills
Malaise
fatique
Confusion or delirium
61
DISCUSSION
Theory Cases
General examination: In this patient, we found:
Fever HR: 140 x/I
Rapid breathing Murmur (+) systolic grade III/6 LMCS III-IV
Cyanosis RR: 42 x/I
Retraction Temp: 38,5oC
Chest indrawing Bronchial
grunting Crackles
Decrease breath Retraction
sounds Grunting
Crackles (rales)
Egophony on Umbilical hernia
auscultation
Pleural frictian rub
Dullness of the chest to
percussion
Altered mental stataus
62
DISCUSSION
Theory Cases
Laboratory test and In this patient, we found:
radiology: Leukocytosis (17.150, 19.360, 20.840)
Leukocyte : normal or Saturation oxygen 86.6% (<90%) may indicated
decrease: viral respiratory distress and hypoxemia
pneumonia, increase: Infiltrate in the lungs with patchy appearance
bacterial pneumonia
Infiltrates. Lobar
pneumonia: an ill
defined area of
increase density,
bronchopneumonia:
infiltrate with patchy
appearance
63
DISCUSSION
Theory Cases
Treatment based on The treatment started from 29th December 2016 until 10th
classification: January 2017. On the 29th December 2016 until 3th January
severe pneumonia. 2017, we gave the patient with:
Bed rest Inj. Ampicillin 300 mg/6hr/IV and Inj. Gentamicin 30
Medical form of antibiotic mg/24hr/IV for antibiotics while waiting for blood
inj. Ampicillin 300 mg / cultures.
6hr / iv and inj.Gentamicin Paracetamol drop 3 x 60 mg
30 mg / 24hr / iv valproic acid syr 3 x 1 cc
Antipyretic use and the supplements vitamin B and C. but the patient
paracetamol drop 3 x 60 did not respond to the drug. The symptoms such as
mg (0.6 cc) dyspneu, cough, and fever not improve.
Anti-seizure use of valproic
acid syr 2 x 1 cc
Sup vit. B complex 1x1 tab
and vit.c 1x50 mg tab.
64
DISCUSSION
Theory Cases
Ceftriaxone should be used as On the 4th January 2017, the blood culture result is
a second-line treatment in negative. But in routine clinical practice, a negative blood
children with severe result is almost inevitable for a large proportion of blood
pneumonia having failed on cultures because of submission of an inadequate volume of
the first-line treatment. blood. The lab result for leukocytes is more than normal
(6.000-17.000), we assumed that the cause of pneumonia
in this patient is bacteria. We change the treatmet with
Inj. Ceftriaxone 300 mg.12hr/IV on 4th January 2017, and
the patient have improvement in symptoms.
65
SUMMARY
AKZ, a 1 year 17 days old girl, BW 6 kg BH 59 cm, came to
USU Hospital on December 28th at 02.45 PM. Her main complaint
was shortness of breath and diagnosed with Bronchopneumonia +
Ventricular Septal Defect (VSD) + Palatoschizis + Epilepsy +
Umbilical Hernia and got fluids IVFD D5% NaCl 0,225% and
medical form of antibiotic inj. Ampicillin 300 mg / 6hr / iv and
inj.Gentamicin 30 mg / 24hr / iv, antipyretic use paracetamol drop 3
x 60 mg (0.6 cc), anti-seizure use of valproic acid syr 2 x 1 cc, and
form of supplements vit. B complex 1x1 tab and vit.c 1x50 mg tab.
66
THANK YOU!
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