Risk Ratio

Ischemic Heart
NRT Varenicline Bupropion
Disease
Positive 2148 594 52
Negative 50141 24834 3194
The risk ratio for subjects contracting Ischemic Heart Disease using NRT
compared to Varenicline is 0.0428/ 0.0239= 1.76.
The risk ratio for subjects contracting Ischemic Heart Disease using Varenicline
compared to Bupropion is 0.0239/0.0163 = 1.46.
This shows that subjects using NRT has the highest chance contracting Ischemic
heart disease as compared to Varenicline and Bupropion. Bupropion has the
lowest chance amongst the 3 treatments.

Heart Failure NRT Varenicline Bupropion

Positive 302 52 7
Negative 52403 25536 3255

The risk ratio for subjects having Heart Failure using NRT compared to
Varenicline is 0.00576/ 0.00204 = 2.82.
The risk ratio for subjects having Heart Failure using Varenicline compared to
Bupropion is 0.00204/ 0.00215 = 0.946.
This shows that subjects using NRT has the highest having Heart Failure as
compared to Varenicline and Bupropion. Varenicline has the lowest chance
amongst the 3 treatments
Peripherial Vascular Disease NRT Varenicline Bupropion
Positive 430 123 14
Negative 52419 25440 3245

The risk ratio for subjects contracting Peripherial Vascular Disease using NRT
compared to Varenicline is 0.00820/ 0.00483 = 1.61.
The risk ratio for subjects contracting Peripherial Vascular Disease using
Varenicline compared to Bupropion is 0.00483/ 0.431= 1.12.
This shows that subjects using NRT has the highest chance contracting Peripherial
Vascular Disease as compared to Varenicline and Bupropion. Bupropion has the
lowest chance amongst the 3 treatments.

Arrhythmia NRT Varenicline Bupropion

Positive 563 126 14
Negative 52252 25435 3246

The risk ratio for subjects contracting Arrhythmia using NRT compared to
Varenicline is 0.0108/ 0.00495 = 2.16.
The risk ratio for subjects contracting Arrhythmia using Varenicline compared to
Bupropion is 0.00495/ 0.00431= 1.14
This shows that subjects using NRT has the highest chance contracting Arrhythmia
as compared to Varenicline and Bupropion. Bupropion has the lowest chance
amongst the 3 treatments