MICROFLUIDICS

PRESENTED BY:
V.Vinoth Kumar
M.sc(Tech)physics 1 year
Roll no:155925

Guided By: V.Jayalakshmi

Content:
Introduction.
Microfluidics.
Emulsion.
Emulsion using Microfluidics.

INTRODUCTION:

How fluid can mixed together to make a new types of structure or

material?
WHAT IS MICROFLUCIDICS?

Microfluidics is the science and technology of manipulating

and controlling fluids, usually in the range of
micro liters (10-6) to pico liters (10-12), in networks of channels
with lowest dimensions from tens to hundreds micrometers.

 Microfluidics emerged in the beginning of the 1980s and is used

in the development ofinkjet
Today:
DNA Chips.
Lab-on-chip technology.

Micro means:
small volumes (L, nL, pL, fL)
small size
low energy consumption

What is Emulsion?
An emulsion is a mixture of two immiscible liquids, where
one liquid is dispersed in the form of small drops in another
liquid eg:oil-in-water or water in oil

Controlled single emulsions:

Microfluidic the order of tens of micrometers. The
drops are formed in another immiscible liquid.

How this principle is implemented in a capillary microfluidic

device and then describe its implementation in more conventional
polydimethylsiloxane (PDMS) devices.

Capillary microfluidic devices

Controlled multiple emulsions:

Multiple emulsion are complex system which consists of both w/o
and o/w at the same time.
w/o/w multiple emulsion are system where small water droplets
are entrapped within larger oil droplets and they are disperse
continuous water phase.
Because of presence of reservoir phase that can be use to prolong
release of active ingredients.

Fig1 :flow focusing

New materials

Combines co-flow and flow-focusing to create double

emulsions.

Ex
te
nd
ed
je
tti
ng
Sh
or
te
ne
d
je
tti
ng
Dr
ip
pi
ng

Jetting
Dripping
Inner fluid

Jetting

BENEFITS OF MICROFLUIDICS:
Scaling law for new effect and better performance.
Reduction in material& power budget,faster device.

DIFFERENT MICROFLUDICS COMPONENTS:

MICROPUMPS
MICROFLOW SENSORS
MICROPARTICLE SEPERATOR.
MICRORECTOR.

APPLICATION OF CONTROLLED MULITIPLE EMULSION:

Application in therapeutics &cosmetics:
Multiple emulsion system are finding unlimited uses because
of their vesicular structure with innermost phase closely similar to
that of liposomal vesicles and the the selective permeability
characteristic of liquid membrane.
In cancer therapy.
In herbal drugs.
In taste masking.
In food industry.
In drug over dosage treatment.

CHALLENGES :
MANUFACTURING:
Reliable,cheap,and repeatable.
INTERFACE & EASE OF USE:
lab on chip and chip in lab.
lab on chip:
Medical.
Biosensors printed directly on clothes.
Intelligent biosensors.
KILLER APPLICATION:
Strong business case for a product.

CONCLUSION:

It is useful for a variety of applications ranging from microparticle

fabrication to vesicle formation, and chemical synthesis to high-throughput
screening of single cells.