Scribd Logo
Carica

Benvenuto in Scribd!

  • Infant of Diabetic Mother

    Caricato da

    Mithlesh Dewangan
    25 visualizzazioni1 pagina
    Infants born to mothers with diabetes are at risk for several complications. Maternal hyperglycemia can act as a teratogen and cause spontaneous abortions and malformations in the fetus. It can also cause fetal hyperglycemia and hyperinsulinemia, leading to increased birth weight (macrosomia). Complications seen in these infants include premature delivery, respiratory issues like respiratory distress syndrome, cardiac defects, hypoglycemia, hypocalcemia and polycythemia. Workup and management depends on the infant's presentation but may involve monitoring blood sugars, treating hypoglycemia, and managing electrolyte abnormalities or other issues like jaundice that require phototherapy or hydration.

    Descrizione originale:

    infant of diabetic mother

    Copyright

    © © All Rights Reserved

    Formati disponibili

    PPT, PDF, TXT o leggi online da Scribd

    Hai trovato utile questo documento?

    Questo contenuto è inappropriato?

    Segnala questo documento
    Infants born to mothers with diabetes are at risk for several complications. Maternal hyperglycemia can act as a teratogen and cause spontaneous abortions and malformations in the fetus. It can also cause fetal hyperglycemia and hyperinsulinemia, leading to increased birth weight (macrosomia). Complications seen in these infants include premature delivery, respiratory issues like respiratory distress syndrome, cardiac defects, hypoglycemia, hypocalcemia and polycythemia. Workup and management depends on the infant's presentation but may involve monitoring blood sugars, treating hypoglycemia, and managing electrolyte abnormalities or other issues like jaundice that require phototherapy or hydration.

    Copyright:

    © All Rights Reserved
    Scarica in formato PPT, PDF, TXT o leggi online su Scribd
    Segnala contenuti inappropriati
    25 visualizzazioni1 pagina

    Infant of Diabetic Mother

    Caricato da

    Mithlesh Dewangan
    Infants born to mothers with diabetes are at risk for several complications. Maternal hyperglycemia can act as a teratogen and cause spontaneous abortions and malformations in the fetus. It can also cause fetal hyperglycemia and hyperinsulinemia, leading to increased birth weight (macrosomia). Complications seen in these infants include premature delivery, respiratory issues like respiratory distress syndrome, cardiac defects, hypoglycemia, hypocalcemia and polycythemia. Workup and management depends on the infant's presentation but may involve monitoring blood sugars, treating hypoglycemia, and managing electrolyte abnormalities or other issues like jaundice that require phototherapy or hydration.

    Copyright:

    © All Rights Reserved
    Scarica in formato PPT, PDF, TXT o leggi online su Scribd
    Segnala contenuti inappropriati
    di 1

    INFANT OF DIABETIC MOTHER

    Mithlesh Dewangan, Syed Manazir Ali,Uzma Firdaus


    Department of Pediatrics , AMU, Aligarh

    INTRODUCTION
    Frequency: 3-10% of pregnant women
    have diabetes
    88% have gestational diabetes
    12% have known diabetes
    35% with Type I diabetes
    65% with Type II diabetes

    MECHANISM OF FETAL EFFECTS


    Maternal hyperglycemia acts like a teratogen ->
    spontaneous abortions and malformation
    Intermittent maternal hyperglycemia causes
    fetal hyperglycemia -> premature maturation of
    fetal pancreatic islet cells -> hyperinsulinemia in
    the fetus
    Increased insulin -> macrosomia -> increased
    metabolic rate -> increased O2 consumption ->
    relative hypoxia in the fetus -> Stimulates
    erythropoietin -> polycythemia
    May be contributing factor to 20-30% stillbirth
    rate in poorly controlled diabetics

    COMPLICATIONS
    Complications At Delivery
    Premature delivery
    Perinatal asphyxia
    Birth injury
    Neonatal effects seen in 0.6% to 4%
    of diabetic pregnancies
    Metabolic
    Macrosomic or IUGR
    LGA
    SGA

    Cardiac
    VSD

    TGA

    Hematologic
    Polycythemia
    Hyperbilirubinemia
    Birth Injuries
    Shoulder dystocia,facial
    brusing,cephalhematoma

    Hypertrophy Cardiomyopathy

    WORKUP AND MANAGEMENT


    Neurologic
    Anencephaly and caudal regression
    syndrome
    Hypoglycemia
    Hypocalcemia
    Hypomagnesemia
    Respiratory
    RDS
    TTN
    GI anomalies
    Situs inversus, atresias,
    small left colon syndrome: presents like
    Hirschsprung disease
    GU anomalies
    Renal agenesis and other urinary tract
    abnormalities

    Follow blood sugars


    If SGA or LGA, also check hematocrit
    Further work-up and management
    depends on patients clinical presentation
    and physical exam
    Hypoglycemia early feeding or IVFs
    with dextrose
    Symptomatic electrolyte abnormalities
    replete electrolytes
    Respiratory distress
    Cardiopulmonary support, CXR/echo
    to search for cause
    Hyperbilirubinemia phototherapy
    Polycythemia IVF hydration or
    exchange transfusion
    Neuro/GI/GU anomalies imaging
    studies, specialist consult

    Potrebbero piacerti anche