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13
1
H and 13C NMR compared:
13
C requires FT-NMR because the signal for a
carbon atom is 10-4 times weaker than the
signal for a hydrogen atom
a signal for a 13C nucleus is only about 1% as
intense as that for 1H because of the magnetic
properties of the nuclei, and
at the "natural abundance" level only 1.1% of
all the C atoms in a sample are 13C (most are
12
C)
H and 13C NMR compared:
1
13
C signals are spread over a much wider
range than 1H signals making it easier to
identify and count individual nuclei
Figure #1 shows the 1H NMR spectrum of 1-
chloropentane; Figure #2 shows the 13C
spectrum. It is much easier to identify the
compound as 1-chloropentane by its 13C
spectrum than by its 1H spectrum.
Figure #1 1
H
ClCH2 CH3
ClCH2CH2CH2CH2CH3
10.0 9.0 8.0 7.0 6.0 5.0 4.0 3.0 2.0 1.0 0
ClCH2CH2CH2CH2CH3
a separate, distinct
peak appears for
each of the 5
carbons CDCl3
23
138
OH
61
O
202
OH
23 61
O
138 202
RCH3 0-35
R2CH2 15-40
R3CH 25-50
R4C 30-40
Table 2
Type of carbon Chemical shift (δ), Type of carbon Chemical shift (δ),
ppm ppm
RCH2Br 20-40
RCH2Cl 25-50
RCH2NH2 35-50
RCH2OH 50-65
RCH2OR 50-65
Table 4
Type of carbon Chemical shift (δ), Type of carbon Chemical shift (δ),
ppm ppm
RCH2Br 20-40 O
RCH2NH2 35-50 O
RCH2OH 50-65 RCR 190-220
RCH2OR 50-65
C NMR and Peak Intensities
13
Distortionless Enhancement
of Polarization Transfer
Measuring a 13C NMR spectrum involves
CCH2CH2CH2CH3
CH CH
CH2
CH CH2
O
CH2 CH3
C
C
CCH2CH2CH2CH3
CH CH
CH3
CH
CH2 CH2
CH2
200 180 160 140 120 100 80 60 40 20 0
CCH2CH2CH2CH3
CH CH
CH3
CH
CH and CH3
unaffected
CH2 CH2
C and C=O nulled CH2
CH
200 2 inverted
180 160 140 120 100 80 60 40 20 0