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Conjunctiva sac :
Bulbar conjunctiva
fornix
medial semilunar fold
palpebral conjunctiva
(tarsal conjunctiva)
Histology :
conjunctival epithelium :
Substansia propia :
adenoid layer
fibrous layer
Bacteriology :
Never free from microorganism
Bacteria do not propagate
(proliferate) easily, due to :
Bacteriology :
Microorganism that could be found in
normal conjunctival sac :
Staph. epidermis
Staph. aureus
Micrococcus sp
Corynebacterium sp
Propionibacterium acnes
Streptococcus sp
Haemophylus influenza
In children
Moraxella sp
Enteric gram (-) bacilli
Bacilus sp
Anaerobic bacteria
Yeast
Filamentous fungi
Demodex sp
Classification of
conjunctival Disorder
Parsons
Inflammations
Infection
Allergy
Degenerative changes
Symptomatic condition
Cyst and Tumors
General Ophthalmology
Conjunctivitis
infection
allergy
autoimmune
chemical / irritates
unknown cause
Degenerative disease
Miscellaneous disorders
Tumors
Clinical terms :
hyperemia = focal / diffuse dilatation of
subepithelial plexus of conjunctival
blood vessels
chemosis = conjunctival edema
tearing = excess tears from increased
lacrimation or impaired lacrimal outflow
discharge = exudates on the
conjunctival surface: serous, mucoid,
mucopurulent, purulent
hyperemia
secret
Secret :
serous : viral
mucous, mucopurulent : bacteria
purulent : beware of gonococcus
Infection of the
conjunctiva
Acute :
serous
catarrhal
mucopurulent
purulent
membranous
chronic :
simple chronic conjunctivitis
angular conjunctivitis
follicular conjunctivitis
Acute Catarrhal or
muco-purulent
Hyperemia
that associated with a mucous discharge
conjunctivitis
---> gums lid together (especially in the morning)
Treatment :
bacteriostatic drop
the eyes should not be bandaged
dark google should be worn if photophobia is
present
care must be taken due to contagious disease
Prognosis :
Most of cases are good
Neglected cases are treated as chronic
conjunctivitis
Purulent conjunctivitis
Occurs in two forms :
Babies : ophthalmia neonatorum
Adult : conjunctivitis
Treatment :
appropriate systemic and topical antibiotic
the eyes should be irrigated with warm
saline and intensive solution of crystalline
benzylpenicilin if any purulent discharge
present
should be directed first to protection of to
other eye
In Cicendo Eye Hospital :
cefotaxime I.m.
gentamycine or sulfacetamide eye drops
Ophtalmia Neonatorum
found in newborn children due to
maternal infection
responsible for 50% of blindness in
children
E/ :
Severe : N. gonorrhea
Mild :Chlamydia oculogenitalis,
Streptococcus pneumonia
Clinical findings :
conjunctiva : inflamed, bright red, swollen, yellow
pus
at severe muco-purulent conjunctivitis : infiltration
at bulbar conjunctiva & lids are swollen and tense
corneal ulceration if untreated
Prophylaxis:
Treatment
Membranous
conjunctivitis
Clinical findings :
mild cases : swelling of the lids, muco-purulent
or serous discharge
severe cases : lids are more brawny, conjunctiva
is permeated w/ semisolid exudates, tend to
necrotize conjunctiva and cornea
Treatment :
treated as diphtherial : penicillin and
antidiphtheritic serum (4-6-10.000 units
repeated in 12 hours)
Simple chronic
conjunctivitis
Continuation of simple
acute conjunctivitis
Etiology :
Symptoms :
burning and grittiness
(especially in the evening)
difficult to keep eyes open
posterior conjunctival
vessels are seen to be
congested
Treatment :
This consist in eliminating the cause
and restoring the conjunctiva to its
normal condition.
Swab should be taken
short course of suitable antibiotic
Follicular conjunctivitis
Inclusion conjunctivitis
Relatively acute onset
hypertrophy is always prominent in
the lower lid
E/ : chlamydial infection
relatively benign
healing spontaneously in from 3 to 12
months
topical broad spectrum antibiotics
systemic Antibiotics (tetracycline 250
mg every 6 hours for 14 days)
Epidemic kerato-konjunctivitis
characterized by a rapidly developing follicular
conjunctiva
associated with pre-auricular adenopathy
may lead to corneal complication
associated with adenovirus
Treatment by adenine arabinoside (Ara-A) is promising
Trachoma
E/ : Chlamydia trachomatis
occuring in 4 stage
trachomatous pannus may
develops at a later stage
Stage of Trachoma
Stage 1: earliest stage, before clinical
diagnosis is possible
WHO:
TF: folicular conjunctival inflammation
TI: diffuse conjunctival inflammation
TS: tarsal conjunctival scarring
TT: trichiasis or enteropion
CO: corneal opacification
Treatment :
the ideal has not been developed
tetracycline, erythromycin,
rifampicin and sulfonamides are
efective
pannus requires no special treatment
corneal complication (ulcers) must be
treated on general principles
Allergic type of
Conjugtivitis
Eczematous conjunctivitis
characterized by one or more small grey or
yellow nodules on the bulbar conjunctiva
frequently complicated by muco-purulent
conjunctivitis
E/ : endogenous bacterial protein
Symptoms : discomfort and irritation
associated with reflex lacrimation
Treatment : Steroid drop or ointment
Vernal conjunctivitis
two types :
palpebral form
bulbar form
Treatment :
symptomatic
steroid drops or ointment
cryotherapy (for nodule)
mast cell stabillizer
Disodium cromoglycate 2%
(adjuvant to topical steroid)
Degenerative Changes
Lithiasis
hard yellow spots in the palpebral
conjunctiva
common in elderly people
removed with sharp needle
Pinguecula
triangular patch on conjunctiva
looks like fat (yellow color)
no treatment required
Pterygium
proliferate subconjunctival
tissue as vascularized
granulation to invade the
cornea
frequently follow a pinguecula
Bare sclera
Simple clossure
Sliding flap
Rotational flap
Conjungtival graft
Symptomatic condition
Subconjunctival ecchymosed
due to rupture of small vessels
the blood becomes absorbed without
treatment in 1 - 3 weeks
Chemosis
edema of conjunctiva
occur in :
acute inflammation
obstruction to the circulation
abnormal blood condition
Xerophthalmia
Clinical findings :
bitots spots
lymphangiectasis
lymphangiomata
Subconjunctival cysticercus ---> rare
hydatid cysts ---> rare
Epithelial implantation cysts ---> rare,
occur after injuries or strabismus
operations
Tumors
Congenital tumors
Dermoids
Dermo-lipomata
Large papillae
papillomata
simple granulomata
eptheliomata
Pigmented tumors
Naevi
Precancerous melanosis
Malignant melanoma
Rodent ulcer
References
Stephen J.H. Miller, Parsons Disease
of The Eye
D, Vaughan, General Ophthalmology
American Academy of
Ophthalmology, External Disease
and Cornea