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Allergic rhinoconjunctivitis
Asthma
Atopic dermatitis
Food reactions such as those
manifested by anaphylaxis,
immediate acute urticaria, or acute
flare of eczema
Suspected latex allergy
Conditions in which specific IgE is
considered likely to play a pathogenic
role (eg. selected cases of chronic
urticaria if the history suggests an
exogenous allergic cause)
Rarer disorders such as allergic
bronchopulmonary aspergillosis,
eosinophilic oesophagitis or eosinophilic
gastroenteritis
Indication
Indication
ofof
SPT
SPT
Patient age
Contraindications
Drugs that interfere with the skin prick test response
PATIENT AGE
Contraindications
Diffuse dermatological conditions
Severe dermatographism
Poor subject cooperation
Subject unable to cease
antihistamines/other interfering
drugs
The
Thenegative
negativecontrol
controlisisthe
thesame
samesolution
solutionas
asthe
theallergens
allergensare
aremade
made
up
upin,
in,eg.
eg.saline
salinebuffer/50%
buffer/50%glycerol,
glycerol,without
withoutany
anyallergen.
allergen.ItItisisalso
also
available
availablecommercially
commercially
The
Thepositive
positivecontrol
controlcan
canbe
beaasolution
solutionofofhistamine
histamine(usually
(usuallyhistamine
histamine
phosphate
phosphate10mg/ml)
10mg/ml)(directly
(directlyinduces
inducescutaneous
cutaneouswheal
whealand
andflare
flare
response)
response)ororcodeine
codeine(usually
(usually9%
9%solution)
solution)(degranulates
(degranulatescutaneous
cutaneous
mast
mastcells,
cells,indirectly
indirectlycausing
causingwheal
whealand
andflare).
flare).Availability
Availabilityofofpositive
positive
control
controlsolutions
solutionsisisproblematic
problematic
Sharp lancets are used to prick through the drop into the
epidermis and superficial dermis.
Some devices consist of a point on a flat stopper, so that the
device can be jabbed onto the patients skin entering the
epidermis and upper dermis, without penetrating too deeply.
A sharp pointed device such as a prick lancet can be used with
an oblique prick and lift technique, without inserting the needle
too deeply.
The prick should not be deep enough to draw blood, although in
the elderly with thin skin this may be unavoidable.
Gloves (latex
and latex-free)
Allergen
extracts
Positive and
negative control
solutions
Sterile lancets for
skin pricking
Sharps container for
disposal of lancets
Method
INTERPRETATION
OF SKIN PRICK TEST RESULTS