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What is a drug?
Chemical agent which effects any biological
process
What is Pharmacology…..?
The study of how drugs effect biological systems
Pharmacokinetics Pharmacodynamics
What the body does to drug What the drug does to body
Pharmacology
Pharmacotherapeutics Pharmacocognosy
The study of the use of drugs Identifying crude materials as drugs
Toxicology
Pharmacocognosy
Sources of Drugs
ABSORBED
TO BLOOD
AFTER DESIRED
METABOLISM ACTION GOSE
BIO TRANSFORMATION TO LIVER
Pharmacokinetics
Absorption = the drugs Metabolism
process of entering the (Biotransformation)= the
system. process in which the body
(Blood & Lymph) reacts to the drug.
Toxic dose
Therapeutic Window
C MAX
0 t1/2
T MAX
DRUG CLASSIFICATION
Example:
Chemical Name: 2-(4-isobutylphenyl)-propionic acid
Parenteral
Not within the alimentary canal
Inhalation, IM, SC, IP, topical
Central
Into the brain or spinal cord
Intrathecal, ICV
Routes of Drug Administration
common abbreviations…
PO = per os = oral
Rate of Absorption
Rate of Elimination
Physiochemical properties of the drug
age, sex, species, metabolism, etc…