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Glifosato: Por qu no?

Qu es el glifosato?

Herbicida sistmico no selectivo


En cantidades reducidas puede ser usado
como regulador del crecimiento
Uso aumentado debido ha plantas
resistentes
Degradacin por microbios del suelo a
AMPA

Humanos

(National Pesticide Information Center, 2015)

Plantas

Inhibicin de la EPSP sintasa


lo cual reduce la sntesis de
aminocidos
aromticos
impidiendo el crecimiento
de la planta (National
Pesticide
Information
Center, 2015)
Perdida de coloracin,
Encogimiento de hojas
Muerte del tejido

Toxicidad

Evidencia limitada de linfoma no Hodgkins


(Guyton, et al., 2015)
Incremento de microncleos en
poblaciones colombianas (Bolognesi, et
al., 2009)
Dao cromosomico in vitro

Animales (ratas)

Evidencia suficiente de carcinognesis


Posible hemangiosarcoma
Tendencia al carcinoma del tbulo renal
Incremento del adenoma en los islotes pancreaticos
Una de las formulaciones esta correlacionada con cncer en la piel

Grupo 2-A
limited evidence of carcinogenicity in humans
and sufficient evidence of carcinogenicity in
experimental animals.

Evidencia limitada
Limited evidence means that a positive
association has been observed between
exposure to the agent and cancer but that other
explanations for the observations (called
chance, bias, or confounding) could not be
ruled out.

Resolucin 0006 de 2015 del Consejo Nacional de Estupefacientes

Referencias
American

Cancer Society, 2015. Non-Hodgkin Lymphoma. [Online] Available at: http://


www.cancer.org/cancer/non-hodgkinlymphoma/detailedguide/non-hodgkin-lymphoma-what-is-nonhodgkin-lymphoma
[Accessed 24 August 2015].
Bolognesi, C. et al., 2009. Biomonitoring of Genotoxic Risk in Agricultural Workers from Five
Colombian Regions: Association to Occupational Exposure to Glyphosate. Journal of Toxicology and
Environmental Health, Part A: Current Issues,, 72(15-16), pp. 986-997.
Cressey, D., 2015. Widely used herbicide linked to cancer. [Online] Available at: http://
www.nature.com/news/widely-used-herbicide-linked-to-cancer-1.17181 [Accessed 24 August 2015].
De Roos, A. et al., 2003. Integrative assessment of multiple pesticides as risk factors for nonHodgkins lymphoma among men. Occup Environ Med, 60(e11), pp. 1-9.
Eriksson, M., Hardell, L., Carlberg, M. & Akerman, M., 2008. Pesticide exposure as risk factor for
non-Hodgkin lymphoma including histopathological subgroup analysis. Int. J. Cancer, Volume 123, p.
16571663.
Guyton, K. et al., 2015. Carcinogenicity of tetrachlorvinphos, parathion, malathion, diazinon, and
glyphosate. The Lancet Oncology, Volume 16, pp. 490-491.
McDuffie, H. et al., 2001. Non-Hodgkins Lymphoma and Specific Pesticide Exposures in Men: CrossCanada Study of Pesticides and Health. Cancer Epidemiology, Biomarkers & Prevention, Volume 10,
pp. 1155-1163.
National Pesticide Information Center, 2015. Glyphosate Technichal Fact Sheet. [Online] Available at:
http://npic.orst.edu/factsheets/glyphotech.html [Accessed 25 August 2015].