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Heredity
and
Variation
Built up of
determining
containing
containing
containing
Chromosomes, genes
and DNA
Cik Emy
NUCLEUS
CHROMOSOMES
-threadlike structure
-human beings have 46 (23
pairs
-contain protein and DNA
DNA
- Double helix structure
- -Made up of series of
genes
GENE
- Segment of DNA
-Genetic codes which
determine an organism
characteristics
Mitosis
Definition:
A cell division process in which a
parent cell (original cell) divides
into two identical daughter cells
(new cells)
Occurs in:
Human and animal : somatic cells
Plants: tips of roots and shoots
tp://youtube.co/watch?v=nPG6480RQo0
Stages of mitosis
nucleus membrane
chromatid
Replication of chromosomes
occur.
Each strand of chromosome is
called chromatid.
centromere
http://youtube.co/watch?v=AhgRhXl7w_g&feature=f
or
vst
http://youtube.co/watch?v=cvlpmmvB
_m4
The Importance of
Mitosis
Meiosis
Definition:
A process in which a nucleus of a parent cell
divides into four daughter cells through
two divisions.
The daughter cells will have half the number
of chromosomes in parent cell.
Occurs in reproductive organs to produce
gametes (ovum and sperms):
Human and animals: testes (male) and ovary
(female)
Plants : anthers and ovaries
tp://youtube.co/watch?v=D1_-mQS_FZ0
Chromosomes in the
nucleus shorten, thicken
and more visible.
Chromosomes align
themselves in the centre of the
cell.
The nucleus membrane
disappears.
Chromatids separate and
move to the opposite ends of
the cell.
The cell begins to divide into
two.
Two daughter cells are
produced.
The nucleus membrane
reforms.
Meosis 2
tp://youtube.co/watch?v=eaf4j19_3Zg
The Importance of
Meiosis
1. To
produce
gametes
2. To allow
variation
through :
Crossing
over
process
Independent
assortment
of
chromosom
es
Conclusion Of Mitosis
And
Meiosis
Male
Female
(46 chromosomes)
Sperm
23 chromosomes)
(46 chromosomes)
Meiosis
Fertilisation
Zygote
(46 chromosomes)
Mitosis
Baby
(46 chromosomes)
Ovum
(23 chromosomes)
tp://youtube.co/watch?v=Ba9LXKH2ztU
DIFFERENCES
MEIOSIS
One only
Number of division
Two times
Occur
Replication process
Four
Number of daughter
cells produced
Two
Number of
chromosomes in
daughter cell
Combination of gene
Occur
Same genes:
Dominant gene and
recessive gene are
placed
opposite to each other
Trait
Dominant
Recessive
Earlobes
Free earlobes
Attached earlobes
Tounge
Ability to roll
Inability to roll
Dimples
Presence
Absence
Hair
Curly
Straight
Iris
colour
Brown
Blue
Height
Tall
Dwarf
The genetic
information of an
organism
Phenoty
pe
The physical
characteristics of an
organism
TT
T
Gametes
tt
t
F1 Generation
Genotype :
Tt
Tall
Phenotype :
Gametes
Tt
Tall
Tt
Tall
Tt
Tall
Tt
Tall
tt
Dwarf
F2 Generation
Genotype :
Phenotype :
TT
Tall
Tt
Tall
Key:
Homozygous: both
genes are
same
Eg: TT, tt
Heterozygous: genes
are
different
Eg: Tt
Exercise 1
In the pea plant, the gene for round
seed(R) is dominant to the gene for
wrinkled seed(r).
a) If a homozygous round-seeded pea
plant is crossed with a homozygous
wrinkled-seeded plant, what will be the
phenotype of F1 plants?
b) If the F1 plants are self-pollinated, what
will be the genotype and phenotype
ratios of the F2 plants?
a)
Key:
R: round seeded
r : wrinkled
seeded
F1 Generation
Rr
Round
Rr
Round
Wrinkled seed
rr
r
Rr
Round
Rr
Round
b)
F1
Generation
Gamet
es
Rr
F2 Genotype
RR
F:2
Roun
Phenotype :
d
Rr
Rr
Rr
rr
Roun
d
Roun
d
Wrinkle
d
Exercise 2
B represents the dominant gene for
black cat, and b represents the
recessive gene for a white cat.
What is the phenotype ratio of the
number of black cats to the number
of white cats if black fur cat (Bb) is
crossed with another black fur cat
(Bb)?
Answer:
Key:
R: black cat
r: white cat
Parents
Gamet
es
F1 Genotype
F:1
Phenotype :
Bb
Rb
BB
Bb
Bb
bb
Blac
k
Black
BlackWhite
Exersice 3
In the pea plant, the gene for purple
flowers (P) is dominant to the gene
for white flowers (p). A cross
between a heterozygous pea plant
with purple flowers and a
homozygous pea plant with
white flowers is done.
What are the genotypes of the
offsprings?
Answer:
Key:
Pp: heterozygous ,
purple flower
pp: homozygous , white
flower
Parents
Gamet
es
F1 Genotype
F:1
Phenotype :
Pp
pp
Pp
Pp
pp
pp
Purpl
e
Purpl
e
Genotype ratio is 2 Pp : 2 pp
White
White
Male: 22 pairs of
autosomes and a pair of
Female: 22 pairs of
autosomes and a pair of sex
Gamete cells:
44 + XY
or
44 + XX
Fertilisation
Baby
Baby girl
boy
44+XX
44+ XY
Mother
Parents :
4
4
2
2
Gametes :
Offsprings: 4
X
X
Daughter
Father
X
X
4
4
2
2
4
4
X
Y
Son
2
2
4
4
X
X
Daughter
X
Y
2
2
4
4
X
Y
Son
NON-IDENTICAL
TWINS
Two different ova
fertilised by two
different sperms at the
same time.
Zygote undergoes
mitosis and separates
into two to develop into
two embryos.
Genetically identical.
Genetically different.
Same sex.
IDENTICAL
TWINS
Zygote
undergoe
s mitosis
Two
embryos
Foetus
share the
same
placenta
NONIDENTICAL
TWINS
Two ova
are
fertilise
d
Two
different
zygotes are
formed
Two
separate
embryos
Each
foetus
has his
own
placenta
Siamese twins
Identical twins that are joined at some
parts of the bodies.
Formed when zygote fails to divide
completely in the course of formation.
IDENTICAL
TWINS
Similarities:
The twins are formed in the uterus.
Two babies are formed.
Differences
One
Number of ova
Two
One
Number of sperms
Two
Yes
Fertilised ovum
splits into two
No
Same / identical
Genetic make up
Different
Yes / sharing
placenta
Sharing of
placenta
No / separate
placenta
Same sex
Sex
Same or different
sex
3.4 MUTATION
Mutation: the spontaneous change
Somatic/body
in
cells
toOccurs
the
structure
of genes or
chromosomes
TYPES
Gene
OFmutation
MUTATION
Examples Of Chromosome
Mutation
Downs syndrome: an extra chromosome
in autosome 21 (47 chromosomes)
Klinefelters syndrome: a male with
extra X chromosome (XXY)
Turners syndrome: a female with one
less X chromosome (XO)
Polyploidy: having one or more
chromosomes in a set of chromosome
Examples Of Chromosome
Mutation
Downs syndrome
Klinefelters syndrome
A male with extra X
chromosomes (having XXY)
Infertile
Underdeveloped testes
Narrow shoulder
Enlarged breasts
Turners syndrome
A female having one less X
chromosome (XO)
Infertile
Short
Mentally retarded
Has no ovaries
Small breasts
Folded skin on neck
No menstrual cycle
Polyploidy
The number of chromosomes is
increased by one or more sets.
More common in plants.
Examples Of Gene
Mutation
Colour blindness
Mutant gene (recessive gene)
on the X chromosome.
Not able to differentiate colours
especially green and red
More common in males because
male has only one X
chromosome
Albinism
The gene for skin colour is
mutated (recessive gene)
Unable to produce melanin
(black pigment)
White hair
Pink eyes and pinkish skin
Skin is sensitive to sunlight
Sickle-cell anemia
Mutation in gene that
produce haemoglobin
Sickle-cell shaped of red blood
cells
Not efficient in transporting
oxygen
Facing painful crises such as
chest pain,
fatigue, bone pain,
Yellowing of eyes
Inherited from both parents
Haemophilia
Mutation in chromosome X
(for blood clotting)
Have problem in blood clotting
May bleed continuously or for
a longer
period
A woman carrier may inherit
the
disease to a son
Causes Of Mutation
Medicine
Field of
Agriculture
To produce higher
yields
To produce high
quality of crops and
livestock
Selective Breeding
A process which involves
cross breeding and cloning
of plants or animals
Advantages
New varieties with
desired
characteristics can
be produced
To produce new
and high quality
crops
More resistant to
diseases
Disadvantages
May produce new
varieties with
undesirable
characteristics
Example 1: Cow
is cross bred
with
Friesian Cow
Sahiwal Cow
Mafriwal Cow
-Grow faster
-Bigger in size
-More milk
-High resistant to
Thin
mesocarp
Thick
mesocarp
is cross bred
with
Large
kennel
Dura
Small
kennel
Pisifera
Tenera
-Thick mesocarp and large kennel :much oil
-Thin shell: easier to extract
Tissue Culture
Advantages
To produce many
To produce many
copies of the
same plants in a
short time
Shorter
maturation time
To produce plants
anytime we want
Disadvantages
No variation
Complete wipeout of crops if
there is spread of
diseases
b) Multiplication:
c) Transplanting:
Process:
Cloning
The process of producing an
organism that is an exact
genetic copy of another
Genetically Modified
Food
Foods from plants and animals
which have had their genetic
information changed by adding
genes from another organisms
Advantages:
For crops:
enhanced taste
and quality,
increased yields,
matures faster,
better resistance
to diseases,
remain fresh
longer
For livestock:
increased
resistance to
infections and
diseases, higher
yield of milk,
meat and eggs
Continuou
s variation
-Characteristics among
individuals which do not
show distinct differences
-Quantitative and can be
measured
-Determined by genes
and can be influenced by
environmental factors
Discontinu
ous
variation
-Characteristics among
individuals which show
distinct differences
-Qualitative and cannot
be measured
-Determined by a single
gene and is not
influenced by
environmental factors
Continuou
s variation
Height
Length
of foot
Intelligenc
e
Skin
colour
Weight
Discontinu
ous
variation
Earlobe
s
Blood
group
Tongue
rolling
Colour
blindnes
s
Iris
colour
Importance Of Variation
DISCONTINUO
US VARIATION
Similarity:
Show differences in characteristics
among individuals of the same
species
Differences
Not distinct
Characteristic
Distinct
Yes
Influenced by
environmental
factors?
No
Inheritance
Can be inherited
No of gene
Single gene
Type of data
Qualitative/
cannot be
measured
If it is influenced
by environmental
factors cannot be
inherited
Two or more
genes for the
same character
Quantitative/ can
be measured
Human cloning:
against religion
Manipulation of
human genes when
carrying out research
on human being