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Built up of
Human
Cells
determining
Characteristics
/ traits
Chromosomes
containing
Genes
containing
DNA
Cik Emy
NUCLEUS
CHROMOSOMES
-threadlike structure
-human beings have 46 (23 pairs
-contain protein and DNA
DNA
-Double helix structure
--Made up of series of genes
GENE
-Segment of DNA
-Genetic codes which
determine an organism
characteristics
Definition:
A cell division process in which a parent cell
(original cell) divides into two identical
daughter cells (new cells)
Occurs in:
Human and animal : somatic cells
Plants: tips of roots and shoots
http://youtube.co/watch?v=nPG6480RQo0
nucleus membrane
chromatid
centromere
http://youtube.co/watch?v=AhgRhXl7w_g&feature=fvst
http://youtube.co/watch?v=cvlpmmvB_m4
or
Vegetative reproduction
such as rhizomes, tubers,
leaves
Definition:
A process in which a nucleus of a parent cell
divides into four daughter cells through two
divisions.
http://youtube.co/watch?v=D1_-mQS_FZ0
Meosis 1
Meosis 2
http://youtube.co/watch?v=eaf4j19_3Zg
1. To produce
gametes
2. To allow
variation
through :
Crossing over
process
Independent
assortment of
chromosomes
(characteristics are separated during
formation of gamete and randomly
combined during fertilization)
Male
(46 chromosomes)
Female
(46 chromosomes)
Meiosis
Sperm
(23 chromosomes)
Fertilisation
Zygote
(46 chromosomes)
Mitosis
Baby
(46 chromosomes)
Ovum
(23 chromosomes)
http://youtube.co/watch?v=Ba9LXKH2ztU
Replication
of DNA
takes place
SIMILARITIES
Cell division
occurs
Involves
division of
nucleus and
cytoplasm
MITOSIS
DIFFERENCES
MEIOSIS
One only
Number of division
Two times
Occur
Replication process
Four
Number of daughter
cells produced
Two
Number of
chromosomes in
daughter cell
Combination of gene
Occur
Dominant gene
Recessive gene
T (tall)
Dominant trait
Recessive trait
Characteristics controlled by
dominant genes
Characteristics controlled by
recessive genes
Same genes:
Dominant gene and
recessive gene are placed
opposite to each other
Trait
Dominant
Recessive
Earlobes
Free earlobes
Attached earlobes
Tounge
Ability to roll
Inability to roll
Dimples
Presence
Absence
Hair
Curly
Straight
Iris colour
Brown
Blue
Height
Tall
Dwarf
Phenotype
Phenotype :
Genotype :
TT
tt
Gametes
F1 Generation
Genotype :
Tt
Tall
Phenotype :
Gametes
Tt
Tall
Tt
Tall
Tt
Tall
Tt
Tall
tt
Dwarf
F2 Generation
Genotype :
Phenotype :
TT
Tall
Tt
Tall
Key:
Homozygous: both genes are
same
Eg: TT, tt
Heterozygous: genes are
different
Eg: Tt
a)
Key:
R: round seeded
r : wrinkled seeded
Parental Phenotype :
Parental Genotype :
Gametes
F1 Generation
Rr
Round
Round seed
RR
R
Wrinkled seed
rr
R
Rr
Round
Rr
Round
Rr
Round
b)
F1 Generation
Gametes
F2 Genotype :
F2 Phenotype :
Rr
Rr
RR
Rr
Rr
rr
Round
Round
Round Wrinkled
Answer:
Key:
R: black cat
r: white cat
Parents
Gametes
F1 Genotype :
F1 Phenotype :
Bb
Rb
BB
Bb
Bb
bb
Black
Black
Black White
Answer:
Key:
Pp: heterozygous , purple flower
pp: homozygous , white flower
Parents
Pp
Gametes
F1 Genotype :
F1 Phenotype :
Pp
Purple
pp
Pp
pp
pp
Purple
Genotype ratio is 2 Pp : 2 pp
White
White
44 + XY
Gamete cells:
or
44 + XX
Y
Fertilisation
Baby
Baby girl
boy
44+XX
44+ XY
Mother
Parents :
44
Gametes :
Offsprings:
22
44
XX
Daughter
Father
XX
44
22
44
XY
Son
22
44
XY
22
XX
Daughter
44
+
Son
XY
IDENTICAL TWINS
An ovum is fertilised by a
sperm to form a zygote.
Zygote undergoes mitosis
and separates into two to
develop into two embryos.
NON-IDENTICAL
TWINS
Two different ova fertilised
by two different sperms at the
same time.
Two different zygotes are
formed and develop into two
embryos.
Genetically identical.
Genetically different.
Share the same placenta.
Each has own placenta.
Same sex.
Same sex or different sex.
Known as fraternal twins.
IDENTICAL TWINS
Zygote
undergoes
mitosis
Two
embryos
Foetus
share the
same
placenta
NON-IDENTICAL
TWINS
Two ova
are
fertilised
Two different
zygotes are
formed
Two
separate
embryos
Each foetus
has his own
placenta
Siamese twins
Identical twins that are joined at some parts of the
bodies.
Formed when zygote fails to divide completely in
the course of formation.
NON-IDENTICAL
TWINS
IDENTICAL TWINS
Similarities:
The twins are formed in the uterus.
Two babies are formed.
Differences
One
Number of ova
Two
two
Number of sperms
Two
Yes
No
Same / identical
Genetic make up
Different
Sharing of placenta
No / separate placenta
Same sex
Sex
3.4 MUTATION
Mutation: the spontaneous change to the
structure of genes or chromosomes
Occurs in
Somatic/body cells
Gametes/reproductive
cells
(inherited)
TYPES OF MUTATION
Gene mutation
Chromosome mutation
Downs syndrome
Additional chromosome at autosome 21.
Physical retardation
Thick neck
Slanted eyes
Protuding tounge
Reduced resistance to diseases
Klinefelters syndrome
A male with extra X chromosomes
(having XXY)
Infertile
Underdeveloped testes
Narrow shoulder
Enlarged breasts
Turners syndrome
A female having one less X
chromosome (XO)
Infertile
Short
Mentally retarded
Has no ovaries
Small breasts
Folded skin on neck
No menstrual cycle
Polyploidy
The number of chromosomes is increased by one
or more sets.
More common in plants.
Colour blindness
Mutant gene (recessive gene) on the X
chromosome.
Not able to differentiate colours
especially green and red
More common in males because male
has only one X chromosome
Albinism
The gene for skin colour is mutated
(recessive gene)
Sickle-cell anemia
Mutation in gene that produce
haemoglobin
Sickle-cell shaped of red blood cells
Not efficient in transporting oxygen
Facing painful crises such as chest pain,
fatigue, bone pain,
Yellowing of eyes
Inherited from both parents
Haemophilia
Mutation in chromosome X (for blood
clotting)
Have problem in blood clotting
May bleed continuously or for a longer
period
A woman carrier may inherit the
disease to a son
Spontaneous changes
during cell division
Exposure to chemical
mutagens: Benzene,
formaldehyde, nicotine,
sodium nitrite, pesticides
Exposure to physical
mutagens: UV radiation,
X-rays, radioactive
radiation
Advantages
Give rise to variation
which leads to
differences in traits
Better chance of
survival when new
species are more
resistant to diseases
Disadvantages
Cause physical
defects
Causes genetic
diseases
Some chromosome
mutations and gene
mutation are lethal
(fatal)
Causes mental
defects
Genetic engineering: to
transfer DNA from one
organism to another
Human genome project:
maps all human genes to
determine genes which
causes diseases
Field of Agriculture
Advantages
Disadvantages
Example 1: Cow
is cross bred
with
Friesian Cow
Sahiwal Cow
Mafriwal Cow
-Grow faster
-Bigger in size
-More milk
-High resistant to disease
Thick
mesocarp
is cross bred
with
Large
kennel
Dura
Small
kennel
Pisifera
Tenera
-Thick mesocarp and large kennel :much oil
-Thin shell: easier to extract
Advantages
To produce many
copies of the same
plants in a short time
Shorter maturation
time
To produce plants
anytime we want
Disadvantages
No variation
Complete wipe-out of
crops if there is spread
of diseases
a) Explant:
b) Multiplication:
c) Transplanting:
Process:
Advantages:
For crops: enhanced
taste and quality,
increased yields,
matures faster, better
resistance to diseases,
remain fresh longer
For livestock:
increased resistance
to infections and
diseases, higher yield
of milk, meat and eggs
Continuous
variation
Discontinuous
variation
-Characteristics among
individuals which do not show
distinct differences
-Characteristics among
individuals which show distinct
differences
Continuous
variation
Height
Length of
foot
Discontinuous
variation
Tongue
rolling
Intelligence
Skin
colour
Blood
group
Earlobes
Weight
Colour
blindness
Iris colour
Genetic factors
Environmental
factors
Independent assortment of
chromosomes: different gametes
Enable us to
distinguish
individuals of the
same species
IMPORTANCE
DISCONTINUOUS
VARIATION
Similarity:
Show differences in characteristics among
individuals of the same species
Differences
Not distinct
Characteristic
Distinct
Yes
Influenced by
environmental factors?
No
If it is influenced by
environmental factors
cannot be inherited
Inheritance
Can be inherited
No of gene
Single gene
Quantitative/ can be
measured
Type of data
Qualitative/ cannot be
measured
The produce of
biological weapon:
anthrax bacteria