H. Ridwan M. Daulay Dr, Sp.A(K) Gabriel Panggabean Dr, Sp.A Wisman Dr, Sp.A Sinusitis is a bacterial infection of the paranasal sinuses Infection occur in any of the paranasal sinuses as they develop Ethmoid & maxillary sinuses are present at birth Sphenoidal & frontal sinuses are not significantly developed until 5 6 yrs Sinus disease in post pubertal adolescent is similar to that in adults Definition S I N U S I T I S Most common cause (90%) : S. pneumonia, H. influenza, M. catarrhalis, S. aureus, S. pyogenes Etiology S I N U S I T I S Mucosa is covered by mucous blanket Flow of mucous is propelled toward ostia, and then nasopharynx Mucus contain IgA, IgG, IgM, and lysozime Paranasal sinuses usually sterile Damage mucociliary function inoculation pathogens infection Pathophysiology S I N U S I T I S Children : as complication of common cold Infection inflammation damage nasal ciliary epithelial cells bacterial colonizing Predisp : - respiratory allergy - dental infection/extraction - defects of ciliary function - cystic fibrosis - immunodeficiency - anatomy - swimming - drying of mucosa Pathophysiology S I N U S I T I S Heralded by failure of common cold symptoms to resolve after 10 days Main symptom is rhinorrhea, purulent Fever > 39 0 C, cough, pain, headache, periorbital swelling (ethmoid), vomiting Acute : unilateral ; chronic : bilateral Common in boys Preschool children : maxillary & ethmoid sinuses Clinical manifestation S I N U S I T I S Orbital infection Meningitis Osteomyelitis Cavernous sinus thrombosis Abscess of epidural, subdural, or brain Complication S I N U S I T I S Nasal culture careful technique Blood : - BSR, band neutrophils Imaging of the sinuses Sinus R > 10 d symptoms, > 1 years old USG CT Scan : - plain film equivocal/negative - chronic/recurrent disease - complications are suspected Investigation S I N U S I T I S Primary treatment : antibiotic started before the results of investigation are known Amoxicillin : S. pneumonia, H. influenza, M. catarrhalis -lactamase producing (H. influenza, M. catarrhalis) : amoxicillin-clavulanate sodium, trimethoprim- sulfamethoxazole, cefaclor Brisk response : 3 4 days Satisfactory : 10 days Response is slower : 1 month Bacterial complication : hospitalized & give parenteral antibiotic iv cefuroxime Management S I N U S I T I S Vasoconstrictive drug ? Topical rebound vasodilatation - only there is considerable pain - no more than 3 days Surgical : - rarely in children - lack of response to maximal medical therapy - continuing symptoms - neurologic complications Management S I N U S I T I S