ENDOCRINE AND METABOLIC SYSTEM

( 7 SKS )
Dr. A. Makbul Aman
Sistem Endokrin dan Metabolisme
Fakultas Kedokteran Universitas
Hasanuddin
What is the Endocrine System ?
1. A chemical messener or hormone !roduced by an
oran is released into circulation to !roduce an e""ect
on a distant taret oran
#. An interated net$ork o" multi!le orans derived "rom
di""erent embryoloic oriins that release hormone
ranin "rom small !e!tides to lyco!rotein $hich
e%ert their e""ects either in neihborin or distant taret
cells
&. 'hree basic com!onent make u! the core o" the
endocrine system (
a. Endocrine land
b. Hormone
c. 'aret orans
Definii!n"
)
Endocrinoloy* the study o" hormone and
landular abnormalities* diabetes+ thyroid
!roblems+ and circus !er"ormers
)
Hormones* bioloically active substances
secreted by lands.
,
Endocrine* hormones that have a bioloical
e""ect "ar a$ay.
,
-aracrine * hormones that have a bioloical
e""ect nearby.
,
Autocrine * hormones that have a local e""ect
'he endocrine oran are located throuhout the body
Some o" the key "unctions o" EM System include (
)
.eulation o" sodium and $ater balance and control o"
blood volume and !ressure
)
.eulation o" calsium and !hos"at balance to !reserve
e%tracellular "luid concentrations re/uired "or cell membrane
interity and intracellular sinalin.
)
.eulation o" enery balance and control o" "uel
mobili0ation+ utili0ation and storae to ensure that cellular
metabolic demand are met.
)
1oordination o" the host hemodynamic and metabolic
counterreulatory res!onses to stress
)
.eulatory o" re!roduction+ develo!ment+ ro$th and
senescence.
2s to coordinate and interate cellular activity $ithin the
$hole body by reulatin cellular and oran "unction
throuhout li"e and maintain homeostasis.
Hemodynamic and metabolic counterreulatory res!onse
to stress
MOD#L
1. 3iabetes Mellitus (
1.1. 'y!e 1 3iabetes
1.#. Screenin and dianosis ty!e # 3M
1.&. 2F4524'
1.6. 1oma ( KA3 and H781+ 9actic acidosis
1.:. 43M
1.;. 3iabetic Foot
1.<. 3M and 2ts .elated diseases
1.=. Hy!olycemia
1.>. Micro and Macrovascular com!lications
1.1?. 8euro!athy diabetic
$. M!%ul Obe"i& an% MeS&n
#.1. 7besity and metabolic diseases
#.#. -17S
#.&. 9i!idoloy
#.6. 'he A32-7SE 'issue
'. MOD#L INTE(RATED CASES
&.1. Steroids and its related to metabolic and
endocrine diseases
&.#. 7steo!orosis
&.&. 1ardio*Metabolic 3iseases

6. 'H@.723
6.1. 4raveAs 3isease
6.#. Hy!othyroidism B Hashimoto+ thyroiditis etc C
6.&. -eriodic !aralysis thyroto%icosis B --'C
6.6. Hy!o and hy!erthyroid in !renancy
6.:. 'hyroid Storm
6.;. 'hyroid 8odule
6.<. 233
). MOD#L *ARAT+YROID (
:.1. Hy!ocalcemic 1risis
:.#. Hy!ercalcemia
:.&. Metabolic bone disease
,. MOD#L *IT#ITARY
;.1. Acromealy 5 4iantism
;.#. S2A3H
;.&. Hy!er!rolactinemia
;.6. 3iabetes 2nsi!idus
;.:. Em!ty Sella Syndrome
;.;. 1ushin disease
7. ADRENAL (
<.1. Addison disease
<.#. 1ohn Syndrome
<.&. Adrenal crisis
<.6. Feochromacytoma
=. Modul -aediatric Endocrinoloy
=.1. -ediatric ro$th and develo!ment
=.#. 3isease o" !ituitary in child and adolescent
=.&. Hy!o and hy!erthiroidism in child
=.6. Adrenal diseases in child
=.:. Se%ual dys"unction in child
A-r!me.al&
Cushings Syndrome
'o!ic o" 1S9
1. 'hyroid E%amination
#. Antrho!ometric
&. 2nsulin 2nDection
'hyroid e%amination
T/e in"ulin in0e-i!n"
'o!ic o" -E9
1. Weiht loss (
a. 4ravesA 3iseases
b. 3iabetes Mellitus
#. -olyuria (
a. 3iabetes 2nsi!idus
&. 7besity (
a. Metsyn
b. Acromealy

EFA9UA'278
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T O T A L ,) 2$ 2$ 2$
T/e Dream Team
*r!f. Dr. 3!/n M4 A%am Dr. 3umraeni T
*r!f.Dr. +ar"inen Sanu"i Dr. +arfia/ D0
*r!f.Dr.Ira5an Yu"uf6 */D Dr. +abiba/6S
*r!f. DR.%r. Sur&ani A Dr. A.u" *. Samb!
*r!f.DR.%r. Nur *u0i A Dr Ar/ur K!"5an%i
DR.Dr. Sari!n! Dr. R!"%iana Na"ir
Dr. A. Makbul Aman Dr. +u"aini #mar
Dr. Trul& Da"ril Dr. R!ber S
Dr. Y!"e1/in T
Dr. A%riani Ba0i