Helping Babies Breathe A healthy first cry represents a baby with unlimited potential Golden minute At no other time in ones life will necessary critical concepts in resuscitation have a potential lifelong impact A babys first cry is one of the most anticipated and welcome sounds in all the world
Appropriate interventions can make the difference between life or death, or normal life vs. life of disability
Inverted Pyramid of Neonatal Resuscitation Medications Chest Compressions Positive-Pressure Ventilation Initial Steps: Drying, Warmth, Clearing the Airway, Stimulation Assessment at Birth and Simple Newborn Care All infants Some infants Few infants Wall, Lee, Niermeyer et al. IJGO 2009 136 million babies born Approx 10 million babies Approx 6 million babies < 1.4 million babies What Can Go Wrong During Transition Inadequate ventilation; oxygen may not reach blood in lungs Systemic hypotension from excess blood loss or neonatal hypoxia and ischemia Pulmonary arterioles may remain constricted after birth (PPHN) Lack of perfusion and oxygenation may cause brain damage or death
Signs of a Compromised Newborn Depressed respiratory drive Poor muscle tone Bradycardia Tachypnea Persistent cyanosis Low blood pressure
Good tone with cyanosis Bad tone with cyanosis Perinatal Compromise Primary Apnea Oxygen deprivation Period of attempted rapid breathing Primary apnea and dropping HR Will improve with tactile stimulation
Secondary Apnea Continued oxygen deprivation leads to secondary apnea Heart rate and blood pressure fall Secondary apnea cannot be reversed with stimulation Assisted ventilation must be provided
The Theme of Neonatal resuscitation Circle of Evaluation Decision Action Timely manner Team work
TABCs Temperature Airway Suction secretions, assess for anomalies Breathing Stimulate respiratory effort Tactile Bag-mask positive pressure ventilation (PPV) Circulation Assess heart rate Chest compressions if PPV ineffective at restoring heart rate Term gestation
Breathing or crying?
Good tone? YES ROUTINE CARE
Stays with mother Provide Warmth Clear Airway Dry Ongoing evaluation
Initial steps NO Evaluate HR Respirations Warmth Open Airway Dry Stimulate
NRP algorithm (2010) HR below 100, gasping, or apnea? PPV, Spo2 monitoring HR below 100? Take ventilation corrective steps Labored breathing or persistent cyanosis? Clear airway, Spo2 monitoring, Consider CPAP Post Resuscitation Care YES NO NO Yes Ineffective PPV (MR SOPA) HR below 100? Take ventilation corrective steps HR below 60 ? Consider intubation Chest compressions Coordinate with PPV HR below 60 ? i.v. epinephrine Take ventilation corrective steps Intubate if no chest rise! Consider -Hypovolemia - Pneumothorax yes Yes Yes No No Yes Mask Adjustment Reposition head Suction upper airway Open mouth and lift Jaw Pressure increase Airway alternative Plan and prepare for birth Equipment check before birth , you should ask Gestational age Clear fluid How many babies Other risk factor
Need additional equipment Need more people Quick pre resuscitation checklist Warm, dry Suction Auscultate Oxygenate Ventilate Intubate Medicate Thermoregulate Plastic wrap in < 28 wks Polythene wrap or bag up to their necks without drying. Infants should be kept wrapped until admission and temperature check. Management of Meconium 2010 ??? Bag & mask ventilation in MSAF?? If attempted intubation is prolonged and unsuccessfull .
& if there is persistent bradycardia. Indications for PPV Apnea Gasping respirations Heart rate < 100 Positive Pressure Ventilation When done appropriately, PPV should result in improvement in heart rate and color Appropriate size mask and bag Self-inflating vs. flow-inflating bag Forming a good seal with mask Achieve adequate chest rise 40-60 breaths per minute
Positive Pressure Ventilation inflation pressure? initial inflation pressure of 20 cm H2O 30 to 40 cm H2O may be required in some term babies without spontaneous ventilation
Effective Ventilation Bilateral breath sounds Chest movement (HR may rise without visible chest movement, especially with preterm baby) Most important indicator of successful PPV is improving heart rate Use lowest inflation pressure to maintain HR above 100
Ineffective PPV (MR SOPA) Mask Adjustment Reposition head Suction upper airway Open mouth and lift Jaw Pressure increase Airway alternative When to use PULSE OXIMETRY
- Anticipated resuscitation positive pressure respiration is administered - When cyanosis is persistent - When supplemental oxygen is administered
Oximetry and Oxygen Supply For all compromising babies pulse oximetry should be used to detect the preductal saturation and heart rate
28 OXYGEN ASSESSMENT
Insufficient Excessive oxygenation oxygenation
Harmful to neonate
Chest Compressions Compression of sternum 1/3 depth of AP diameter of chest Increase O2 to 100% Chest Compressions Begin chest compressions when HR is below 60 despite at least 30 seconds of effective PPV Coordinate with ppv at 1 :3
Two thumb method is preferred Provides more consistent pressure Better control of compression depth 2-Finger Technique Better for small hands Provides access to umbilicus for medications
Depress sternum to approximately one third of the anterior-posterior diameter of the chest 100% oxygen should be given with chest compressions Continue chest compressions for 45-60 seconds before stopping to evaluate the HR Intubation is highly recommended with chest compressions Endotracheal Intubation Endotracheal Intubation: Indications To suction trachea in presence of meconium when the baby is not vigorous To improve efficacy of ventilation after several minutes of bag-and-mask ventilation To facilitate coordination of chest compressions and ventilation To administer epinephrine while IV access is being established Limit attempt to 30 seconds Endotracheal Intubation: Radiographic Confirmation Correct Incorrect Indications for Epinephrine Heart rate persists < 60 after Initial steps [30 seconds] PPV [30 seconds] Chest compressions [45-60 seconds]
Dosage given IV (UVC preferred), or endotracheal (higher dose given) Epinephrine Administration Dilute 1:1000 concentration of epinephrine to 1:10,000 Recommended concentration: 1:10,000 Recommended route: Intravenously Recommended dose: 0.1 to 0.3 mL/kg Recommended preparation: 1:10,000 solution in 1 mL syringe
Recommended rate of administration: Rapidly
Consider endotracheal route ONLY while IV access being obtained Recommended dose: 0.5 to 1mL/kg Prepare 1:10,000 solution in 3 mL syringe
Epinephrine: Poor Response (Heart Rate < 60 bpm) Recheck effectiveness of: Ventilation Chest compressions Endotracheal intubation Epinephrine delivery Consider possibility of hypovolemia Indications for Volume Administration No response to above resuscitation measures History of blood loss at delivery suggesting hypovolemia Infant appears to be in shock (pallor, poor perfusion, failure to respond appropriately to resuscitation efforts)
IV, 10-20 mL/kg, Normal saline, Ringers lactate, or O- blood
Withhold / discontinue resuscitation?
Age of viability in your institution. Parental informed decision In a newly born baby with no detectable heart rate, it is appropriate to consider stopping resuscitation if the heart rate remains undetectable for 10 minutes Key Points Resuscitation requires a rapid series of assessments, interventions, and reassessments
Prompt initiation of respiratory support with positive pressure ventilation by bag-mask is the key to successful resuscitation of most infants
Always consider corrective steps in ventilation and hypovolemia and pneumothorax (other causes) Recommendation Routine intrapartum oropharyngeal and nasopharyngeal suctioning for infants born with clear and/or meconium- stained amniotic fluid is not recommended. If attempted intubation is prolonged or unsuccessful, mask ventilation should be implemented, particularly if there is persistent bradycardia. The LMA should be considered during resuscitation of the newborn if face mask ventilation is unsuccessful and tracheal intubation is unsuccessful or not feasible.
Endotracheal Intubation Tracheal suctioning for non-vigorous meconium-stained newborn Effective PPV with bag and mask and no clinical improvement PPV lasting more than a few minutes When chest compressions are needed Special indications (diaphragmatic hernia, etc) Use of Oxygen Resuscitation of term newborns should begin with 21% oxygen Resuscitation of preterm newborns may begin with slightly higher oxygen It may take up to 10 minutes for a healthy newborn to become well oxygenated on room air Place oximeter (if available) and increase oxygen gradually to meet target saturations
Umbilical cord clamping For healthy term infants delaying cord clamping for at least one minute or until the cord stops pulsating following delivery improves iron status through early infancy. For preterm babies in good condition at delivery, delaying cord clamping for up to 3 min results in increased blood pressure during stabilisation, a lower incidence of intraventricular haemorrhage and fewer blood transfusions Most infants successfully transfer from intrauterine to extrauterine life without any special assistance. 10 percent of newborns will need some intervention. 1 percent will require extensive resuscitative measures at birth. personnel who are adequately trained should be readily available to perform neonatal resuscitation at every birthing location Infants who are more likely to require resuscitation can be identified by maternal and neonatal risk factors Care providers skilled in neonatal resuscitation should be present and equipment should be prepared prior to the birth of the high-risk infant. Preterm infants are more likely to require resuscitation and develop complications from resuscitation than term infants Please take good care of me! Im the Future!