Definition

Mean corpuscular hemoglobin (MCH)

A measurement of the average weight of hemoglobin in a
red blood cell.

It was the calculated value derived from the measurement
of haemoglobin and the red cell count

Haemoglobin value was the amount of haemoglobin in a
volume of blood while the red cell count was the number of
red blood cell in a volume of blood
The normal range for mean corpuscular
haemoglobin(MCH) was MCH: 27-33 picograms
(pg)/cell in adults and the mean corpuscular
haemoglobin concentration(MCHC) was MCH: 33-36
g/dl in adults.
High MCH
It was considered high when the value was in excess of 34 picograms

When the value was high it show that the person was in suffering from the
macryotic anemia

This disorder was due to lacking of vitamin such as Folic Acid or vitamin
B12.

This vitamin contain abundance of carbon and required for the body to
perform the important chemical and also for the body to function at the
peak level.

Those person that suffer from the macryotic anemia cant produce enough
quantity of red blood cell which mean the person had more haemoglobin
present than ordinary blood cell.
Low MCH
It was considered low when the value was under 26
picograms

When the value was low it show that the person was in
suffering from the micryotic anemia, blood loss,
haemoglobinophaty and lack of acute iron

This disorder was due to lacking of iron

Those person that suffer from micryotic anemia do not
had healthy transportation of oxygen in their bodies.
Introduction To Analysis of Variance
(ANOVA)
- ANOVA is a statistical method used to compare
the means of two or more groups.
- ANOVA contains
i) factors(variables)
ii) levels
- Types of ANOVA:
i) One-way
ii) repeated-measures
iii) Factorial
iv) Two way ANOVA

What need to do??
Total sum of squares= sum of squares between
groups + sum of squares within groups
Degree of freedom
Mean square= sum of square/degrees of freedom
F square= mean square/(sum of square/d.f)
Find critical value from t table
Construct curve diagram
The acceptance of hypothesis

Determine whether there is any significant difference in
MCH values between gender (male and female) and
between age group (<=20 and >20 years old).
H
o
: Gender will have no significant effect on MCH values
H
A
: Gender does have a significant effect on MCH values

H
o
: Age group will have no significant effect on MCH values
H
A
: Age group does have a significant effect on MCH values

H
o
: Gender and age interactions will have no significant effect on MCH values
H
A
: Gender and age interactions does have a significant effect on MCH value
WANTED DATA AGE
<=20 >20 TOTAL
GENDER MALE 1235 540 1775
FEMALE 517 901 1418
TOTAL 1752 1441 3193
TOTAL DATA
UNWANTED
(FLITERED)
644
WANTED DATA 3193
TOTAL 3837
0 AGE
GENDER :
NORMAL
ZERO VALUES OF
MCH
3
subjects
1
subject
640
subjects
Total of 644
subjects
data is
removed
Find sum of squares
Find degree of freedom, df
Calculate the mean of square
Calculate F score
Refer table for Critical Value
Draw Curve diagram
Accept or reject the hypothesis
MEAN AGE
<=20 >20 AVERAGE
GENDER MALE 29.93481 30.08981 30.01231
FEMALE 29.18356 29.09158 29.13757
AVEARGE 29.55919 29.5907 29.57494
SUM OF SQUARES AMOUNT Df MEAN OF
SQUARE
F SCORE
1
ST
FACTOR :
GENDER
610.7970065 2-1=1 610.7970065 59.98545977
2
ND
FACTOR : AGE
GROUP
0.792546712 2-1=1 0.792546712 0.077834826
WITHIN (ERROR) 32471.73 3193-4=3189 10.18241769
BOTH 64.18904679 1x1=1 64.18904679 6.303910208
TOTAL 33147.5086
1
st
Factor Gender :
F(1,3189)= 59.98545977
2
nd
Factor Age :
F(1,3189)= 0.077834826
Both :
F(1,3189)= 6.303910208
3.84
1
st
Factor Gender :
F(1,3189)= 59.98545977
2
nd
Factor Age :
F(1,3189)= 0.077834826
Both :
F(1,3189)= 6.303910208
0.077834826
6.303910208 59.98545977
H
o
: Gender will have no significant effect on MCH values
H
A
: Gender does have a significant effect on MCH values


H
o
: Age group will have no significant effect on MCH
values


H
o
: Gender and age interaction will have no significant
effect on MCH values
H
A
: Gender and age interaction does have a significant
effect on MCH value