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Cellular meta!olism
1u!rication
Normal Fluid 2ains and
1osses
GAINS
Fluid intake 3+..ml
Food intake 3...ml
Nutrient o%idation 4..ml
Losses
Sensi!le5 urine 63+..78 Sweat 63..7
'nsensi!le5 Skin 6+..79 1ungs 6:..79 Feces
6;..7$
Regulatory Mec"anisms
3$<osterior <ituitary5 releases A= 6antidiuretic
"ormone7 in response to increased serum
Osmolality$ A= causes renal rea!sorption o#
water$
Normal Serum Osmolality is 280-295
mosm/kg
and
reflects the concentration of solutes in the blood.
he greater the osmol the greater the !ulling
force "osmotic !ressure#
2. =ypot"almus5 >"irst mec"anism is triggered in
response to increased serum osmolality$
Regulatory Mec"anisms
:,am!les;
+5<NSS
=ypotonic Fluids
E%cessi&e intake o# Na
'ntegumentary5 Edema
Fluid restriction
Sodium restriction
aily weig"tsA'HO
Anions 6,7
M 34+ mE0A1
N 3:+ mE0A1
Cellular meta!olism
Oral <otassium
N+$+
Kaye%alate9 dialysis
'ntake 'ncludes5
'EDs
'E<)