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RISK FACTORS FOR EMERGENCY HOSPITAL ADMISSION FOR DIABETIC KETOACIDOSIS: NATIONAL CROSSSECTIONAL ANALYSIS
Objectives: To determine key demographic and metabolic risk factors that increase the likelihood of hospital admission with diabetic ketoacidosis (DKA) in children and young people with Type 1 Diabetes in England and Wales.
RISK FACTORS FOR EMERGENCY HOSPITAL ADMISSION FOR DIABETIC KETOACIDOSIS: NATIONAL CROSSSECTIONAL ANALYSIS
Data Sources
- NPDA (2008-2010):
The National Paediatric Diabetes Audit (NPDA) reports highlight the main findings on the quality of care for infants, children and young people with diabetes in England and Wales (http://www.rcpch.ac.uk/national-paediatric-diabetes-audit-npda). Includes details on the number of infants, children and young people registered with paediatrics diabetes units in England and Wales and the care processes they receive
RISK FACTORS FOR EMERGENCY HOSPITAL ADMISSION FOR DIABETIC KETOACIDOSIS: NATIONAL CROSSSECTIONAL ANALYSIS
Data Sources
HES and PEDW provide a comprehensive data source for all emergency hospital admissions.
They were used to identify patients that were hospitalised with DKA (ICD10 Code E101)
HbA1c
Deprivation
Covariates
Blood Pressure Ethnicity
BMI Age
Sex
RISK FACTORS FOR EMERGENCY HOSPITAL ADMISSION FOR DIABETIC KETOACIDOSIS: NATIONAL CROSS-SECTIONAL ANALYSIS
Statistical Analysis
Dependent Variable: Number of hospital admissions for DKA Random effects: Paediatric diabetes units
HbA1c
Deprivation
Multilevel
model
Blood Pressure Ethnicity
Black
RISK FACTORS FOR EMERGENCY HOSPITAL ADMISSION FOR DIABETIC KETOACIDOSIS: NATIONAL CROSSSECTIONAL ANALYSIS
Results
Black ethnicity (IRR=1.2) (compared to white) Female sex (IRR=1.13) Poor diabetic control (HbA1c IRR = 1.08) Age (IRR=1.02) Diabetes duration (IRR=1.01) Deprivation (IMD score IRR=1.01)
RISK FACTORS FOR EMERGENCY HOSPITAL ADMISSION FOR DIABETIC KETOACIDOSIS: NATIONAL CROSSSECTIONAL ANALYSIS
Results
Black ethnicity (IRR=1.2) (compared to white) Female sex (IRR=1.13) Poor diabetic control (HbA1c IRR = 1.08) Age (IRR=1.02) Diabetes duration (IRR=1.01) Deprivation (IMD score IRR=1.01)
RISK FACTORS FOR EMERGENCY HOSPITAL ADMISSION FOR DIABETIC KETOACIDOSIS: NATIONAL CROSSSECTIONAL ANALYSIS
Further Work
Hypoglycaemia
Time Trends (2005-2011)